Acute systemic DNA damage in youth does not impair immune defense with aging

An interlaboratory comparison of dosimetry for a multi-institutional radiobiological research project: Observations, problems, solutions and lessons learned

(2015) Thomas M. Seed et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

(2015) Jianhui Chang et al.   NATURE MEDICINE

Total body irradiation causes long-term mouse BM injury via induction of HSC premature senescence in an Ink4a- and Arf-independent manner

(2014) L. Shao et al.   BLOOD

Histone Deacetylation Critically Determines T Cell Subset Radiosensitivity

(2014) J. L. Pugh et al.   JOURNAL OF IMMUNOLOGY

Aging of the T Cell Compartment in Mice and Humans: From No Naive Expectations to Foggy Memories

(2014) Janko Nikolich-Žugich   JOURNAL OF IMMUNOLOGY

Prolonged lifespan with enhanced exploratory behavior in mice overexpressing the oxidized nucleoside triphosphatase hMTH1

(2013) Gabriele De Luca et al.   AGING CELL

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Stressing the cell cycle in senescence and aging

(2013) Hollie Chandler et al.   CURRENT OPINION IN CELL BIOLOGY

Intrinsic defects in CD8 T cells with aging contribute to impaired primary antiviral responses

(2013) Jiu Jiang et al.   EXPERIMENTAL GERONTOLOGY

West Nile virus infection and immunity

(2013) Mehul S. Suthar et al.   NATURE REVIEWS MICROBIOLOGY

Aged-related shifts in T cell homeostasis lead to intrinsic T cell defects

(2012) Laura Haynes et al.   SEMINARS IN IMMUNOLOGY

B cell maintenance and function in aging

(2012) Igor Kogut et al.   SEMINARS IN IMMUNOLOGY

Increased apoptosis, curtailed expansion and incomplete differentiation of CD8+ T cells combine to decrease clearance of L. monocytogenes in old mice

(2011) Megan J. Smithey et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Repeated In Vivo Stimulation of T and B Cell Responses in Old Mice Generates Protective Immunity against Lethal West Nile Virus Encephalitis

(2011) Jennifer L. Uhrlaub et al.   JOURNAL OF IMMUNOLOGY

Innate or Adaptive Immunity? The Example of Natural Killer Cells

(2011) E. Vivier et al.   SCIENCE

Hematopoietic Stem Cell Quiescence Promotes Error-Prone DNA Repair and Mutagenesis

(2010) Mary Mohrin et al.   Cell Stem Cell

Effects of aging on B cell function

(2009) Daniela Frasca et al.   CURRENT OPINION IN IMMUNOLOGY

Key role of T cell defects in age-related vulnerability to West Nile virus

(2009) James D. Brien et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY

T-cell immunosenescence: lessons learned from mouse models of aging

(2009) Alexander C. Maue et al.   TRENDS IN IMMUNOLOGY

RepliVAX WN, a single-cycle flavivirus vaccine to prevent West Nile disease, elicits durable protective immunity in hamsters

(2009) Douglas G. Widman et al.   VACCINE

Long-lasting alterations of the immune system by ionizing radiation exposure: Implications for disease development among atomic bomb survivors

(2007) Yoichiro Kusunoki et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY