Article
Chemistry, Analytical
Dominik Spinczyk
Summary: This study compares different techniques for measuring respiratory motion to address the challenge of liver tumor destruction. The results show variations in accuracy for laparoscopic, skin markers, and skin surface registration methods. We also present clinical techniques and accompanying imaging modalities used for liver tumor destruction, along with their advantages, limitations, and future directions for development.
Article
Chemistry, Analytical
Dominik Spinczyk, Sylwester Fabian, Krzysztof Krol
Summary: This article presents a real-time method for estimating the displacement of the target point due to respiratory movements during minimally invasive procedures. The method uses skin markers and non-rigid registration algorithms, and has been validated using clinical data. The method allows for real-time positioning of the target and estimation of the target position error. In addition, directions for further research and the possibility of combining other methods are discussed.
Review
Chemistry, Multidisciplinary
Peipei Yang, Xin Zhi, Yunxue Xu, Linxue Qian, Zhifei Dai
Summary: Pancreatic carcinoma (PCa) is a highly lethal malignant tumor with limited treatment options. Nanoparticles have been introduced as a medium or carrier to focus energy at the tumor site and minimize side effects. The combination of nanomedicine and minimally invasive techniques provides a new opportunity for the treatment of PCa.
Article
Surgery
Shigeoki Hayashi, Tadatoshi Takayama, Masahito Ikarashi, Ken Hagiwara, Yoritaka Matsuno, Takeki Suzuki
Summary: TAMIS is a safe and feasible procedure for small rNET, with short surgical duration and few postoperative complications. Further studies are needed to fully understand the advantages, disadvantages, and indications of TAMIS for rNET.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Review
Biotechnology & Applied Microbiology
Chunyan Duan, Mingjia Yu, Changji Hu, Hongying Xia, Ranjith Kumar Kankala
Summary: Tissue engineering aims to restore tissue defects using 3D biomimetic pre-formed scaffolds. Micro-sized injectable modularized units have gained interest as ideal delivery vehicles for cells and growth factors due to their minimally-invasive nature and improved cell retention efficacy. This review discusses the progress of these carriers in tissue engineering, highlighting their design and ability to deliver cells and promote tissue growth.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Engineering, Biomedical
Yueying Yang, Zhengyang Yu, Xiaohuan Lu, Jiahao Dai, Cheng Zhou, Jing Yan, Lin Wang, Zheng Wang, Jianfeng Zang
Summary: We have developed a minimally invasive bioprinting system to fabricate electroactive hydrogel scaffolds in partial liver resection of live rats. In situ tissue regeneration is achieved by promoting cell proliferation, migration, and differentiation, as well as maintaining liver function.
BIOACTIVE MATERIALS
(2023)
Article
Biophysics
Yuanyuan Zou, Zhengkang Chu, Jiuchuan Guo, Shan Liu, Xing Ma, Jinhong Guo
Summary: Diabetes and its complications are a major threat to the health and well-being of millions of people. Continuous glucose monitoring (CGM) technology, particularly based on electrochemical sensing principles, has great potential to improve the quality of life of diabetics by overcoming the limitations of self-monitoring blood glucose (SMBG). However, the application of minimally invasive electrochemical CGM sensors is still limited due to issues such as invasiveness, short lifespan, biocompatibility, and calibration and prediction. Recent developments in materials and technologies have significantly improved the performance of these sensors.
BIOSENSORS & BIOELECTRONICS
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Annemarijke van Luijtelaar, Jurgen J. Futterer, Joyce Gr Bomers
Summary: Whole gland prostate cancer treatment has a significant impact on quality of life and may result in over treatment. Minimal-invasive treatment strategies are emerging techniques that aim to reduce complications and morbidity. Imaging plays an important role in targeting and monitoring treatment approaches. Multi parametric magnetic resonance imaging is a widely used image-guided intervention technique.
BRITISH JOURNAL OF RADIOLOGY
(2022)
Article
Biophysics
Margarita Poderyte, Arunas Ramanavicius, Ausra Valiuniene
Summary: In this research, scanning electrochemical microscopy combined with electrochemical impedance spectroscopy was used to achieve irreversible electroporation of active yeast cells and induce cell death. The study demonstrated that cell death could be achieved using relatively low voltages without causing damage to unaffected cells, which is crucial for the development of irreversible electroporation techniques for cancerous tissue treatment.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Ophthalmology
Joel Caballero-Garcia, Carlos Aparicio-Garcia, Yurledys Jhohana Linares-Benavides, Misael Lopez-Sanchez, Franklyn Alain Abreu-Perdomo, Juvenal Huanca-Amaru
Summary: The study evaluated the efficacy of 360 degree minimally invasive endoscopic surgery in patients with orbital intraconal tumors. The surgical approach resulted in successful tumor resection, improved visual function, and relief of proptosis. The clinical outcomes were good in terms of immediate and long-term morphologic and aesthetic results.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2021)
Review
Oncology
Karl-Goran Tranberg
Summary: Current immune-based therapies represent a significant advancement in cancer treatment, but are not universally effective; therefore, physically based local destruction techniques are being used to enhance the outcomes of immunotherapies, with varying effectiveness in inducing systemic anti-tumor immunologic effects.
FRONTIERS IN ONCOLOGY
(2021)
Article
Surgery
Laura Mazer, Patrick Worth, Brendan Visser
Summary: This study reviewed patients undergoing surgery for gastric GIST at a single academic center between 2000 and 2018. The results showed that laparoscopic resection was associated with smaller tumors, lower postoperative complication rates, and shorter length of stay. Different types of resection techniques were identified based on tumor size and location, aiding in the selection of the ideal approach for difficult tumors.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Review
Chemistry, Multidisciplinary
Wang Zhenhua, Ma Cong, Fang Ping, Xu Haichao, Mei Tiansheng
Summary: Organic electrochemical synthesis is an environmentally friendly alternative to traditional organic synthesis, enabling challenging transformations under mild reaction conditions. With increasing awareness of energy efficiency and environmental protection, it has gained much attention. However, electrochemical synthesis faces challenges including electrode passivation, limited reaction types, and difficulty in controlling reactivity and selectivity. This review focuses on recent efforts in addressing these challenges through direct and indirect electrolysis in organic solution systems.
ACTA CHIMICA SINICA
(2022)
Article
Immunology
Amaro Nunes Duarte-Neto, Luiz Fernando Ferraz da Silva, Renata Aparecida de Almeida Monteiro, Jair Theodoro Filho, Thabata Larissa Luciano Ferreira Leite, Catia Sales de Moura, Michele Soares Gomes-Gouvea, Joao Renato Rebellho Pinho, Cristina Takami Kanamura, Ellen Pierre de Oliveria, Kely Cristina Soares Bispo, Cassia Arruda, Aline Brito dos Santos, Flavia Cristina Goncalves Aquino, Elia Garcia Caldini, Thais Mauad, Paulo Hilario Nascimento Saldiva, Marisa Dolhnikoff
Summary: This study conducted 80 autopsies using ultrasound-guided MITS in patients with COVID-19 and found it to be a safe and highly accurate procedure, providing a systemic view of the disease and identifying pathogens effectively. The data showed that US-guided MITS has the capacity similar to CDA not only to identify but also to characterize emergent diseases.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Engineering, Electrical & Electronic
Maria Rosario Pinheiro, Valery V. V. Tuchin, Luis Manuel Oliveira
Summary: This article explores the use of diffuse reflectance (R-d) spectroscopy to evaluate water and sucrose diffusion properties in skeletal muscle during optical clearing treatments. By treating muscle samples with sucrose-water solutions of different osmolarities, collimated transmittance (T-c) and R-d measurements were performed to obtain diffusion time (t) and diffusion coefficient (D) values. The results show that the estimated t and D values for water in the muscle are 63.1s and 1.72x10(-6) cm(2)/s, while for sucrose they are 261s and 4.86x10(-7) cm(2)/s. Comparing these values with the ones estimated from T-c measurements, the relative differences for t and D are 1.6% and 2.8% for water, and 0.3% and 0.4% for sucrose.
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS
(2023)
Article
Oncology
Julia Khriguian, Horacio Patrocinio, Sero Andonian, Armen Aprikian, Wassim Kassouf, Simon Tanguay, Fabio L. Cury
Summary: This study retrospectively assessed the safety and efficacy of SABR in the treatment of UTUC. The results showed that SABR is safe and well-tolerated, with good radiographic tumor response in UTUC.
PRACTICAL RADIATION ONCOLOGY
(2022)
Article
Urology & Nephrology
Ronald Kool, Ivan Yanev, Tarek Hijal, Marie Vanhuyse, Fabio L. Cury, Luis Souhami, Wassim Kassouf, Alice Dragomir
Summary: Trimodal therapy (TMT) is a suitable alternative to neoadjuvant chemotherapy (NAC) and radical cystectomy (RC) for patients with muscle-invasive bladder cancer (MIBC). In this study, a cost-effectiveness evaluation was conducted for RC +/- NAC vs. TMT in the Canadian healthcare system. Results showed that TMT performed in academic centers had higher effectiveness but higher cost, while RC +/- NAC was considered cost-effective at the populational-level.
CUAJ-CANADIAN UROLOGICAL ASSOCIATION JOURNAL
(2022)
Article
Oncology
Talia Malagon, Jean H. E. Yong, Parker Tope, Wilson H. Miller, Eduardo L. Franco
Summary: This study used a microsimulation model to estimate the long-term impacts of cancer care disruptions during the COVID-19 pandemic in Canada. It predicted over 21,000 additional cancer deaths between 2020 and 2030, with the potential to mitigate these losses by increasing diagnostic and treatment capacity in the short term.
INTERNATIONAL JOURNAL OF CANCER
(2022)
Article
Clinical Neurology
Melissa Henry, Raphaele Harvey, Lawrence M. Chen, Michael Meaney, Thi Thu Thao Nguyen, Han-Tin Kao, Zeev Rosberger, Saul Frenkiel, Michael Hier, Anthony Zeitouni, Karen Kost, Alex Mlynarek, Keith Richardson, Celia M. T. Greenwood, David Melnychuk, Phil Gold, Gabrielle Chartier, Martin Black, Marco Mascarella, Christina MacDonald, Nader Sadeghi, Khalil Sultanem, Georges Shenouda, Fabio Cury, Kieran John O'Donnell
Summary: The study investigates the impact of genetic predispositions to depression and inflammation on symptom burden in head and neck cancer patients. It suggests that genetic predisposition, anxiety disorders, and radiotherapy dosage contribute to symptom burden. Early interventions targeting genetic predisposition and psychological factors may help alleviate symptom burden in cancer patients.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Oncology
Daniel J. Krauss, Theodore Karrison, Alvaro A. Martinez, Gerard Morton, Di Yan, Deborah Watkins Bruner, Benjamin Movsas, Mohamed Elshaikh, Deborah Citrin, Bruce Hershatter, Jeff M. Michalski, Jason Alexander Efstathiou, Adam Currey, Vivek S. Kavadi, Fabio L. Cury, Michael Lock, Adam Raben, Samantha Andrews Seaward, Ali El-Gayed, Joseph P. Rodgers, Howard M. Sandler
Summary: This study found that short-term androgen deprivation therapy did not improve the overall survival rates in men with intermediate-risk prostate cancer treated with dose-escalated radiotherapy. However, it did lower prostate cancer-specific mortality, distant metastases, and PSA failure rates.
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Oncology
Benjamin Movsas, Joseph P. P. Rodgers, Mohamed A. A. Elshaikh, Alvaro A. A. Martinez, Gerard C. C. Morton, Daniel J. J. Krauss, Di Yan, Deborah E. E. Citrin, Bruce W. W. Hershatter, Jeff M. M. Michalski, Rodney J. J. Ellis, Vivek S. S. Kavadi, Elizabeth M. M. Gore, Gary S. S. Gustafson, Craig A. A. Schulz, Vikram M. M. Velker, Adam C. C. Olson, Fabio L. L. Cury, Michael A. A. Papagikos, Theodore G. G. Karrison, Howard M. M. Sandler, Deborah W. W. Bruner
Summary: This study reports the patient-reported outcomes of a phase III trial evaluating total androgen suppression combined with dose-escalated radiation therapy for intermediate-risk prostate cancer. The results showed clinically meaningful declines in the hormonal and sexual domains in the RT + TAS group, but these differences disappeared by 1 year.
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Oncology
Stuart J. Wong, Pedro A. Torres-Saavedra, Nabil F. Saba, George Shenouda, Jeffrey M. Bumpous, Robert E. Wallace, Christine H. Chung, Adel K. El-Naggar, Clement K. Gwede, Barbara Burtness, Paul A. Tennant, Neal E. Dunlap, Rebecca Redman, William A. Stokes, Soumon Rudra, Loren K. Mell, Assuntina G. Sacco, Sharon A. Spencer, Lisle Nabell, Min Yao, Fabio L. Cury, Darrion L. Mitchell, Christopher U. Jones, Selim Firat, Joseph N. Contessa, Thomas Galloway, Adam Currey, Jonathan Harris, Walter J. Curran Jr, Quynh-Thu Le
Summary: This study investigated whether adding lapatinib to radiation plus cisplatin for frontline therapy of stage III to IV non-HPV head and neck cancer patients improves progression-free survival.
Meeting Abstract
Urology & Nephrology
Daniel Halstuch, Ronald Kool, Gautier Marcq, Rodney H. Breau, Peter C. Black, Bobby Shayegan, Michael Kim, Ionut Busca, Hamidreza Abdi, Mark T. Dawidek, Michael Uy, Gagan Fervaha, Fabio L. Cury, Nimira S. Alimohamed, Claudio Jeldres, Ricardo Rendon, D. Robert Siemens, Girish S. Kulkarni, Wassim Kassouf, Jonathan I. Izawa
JOURNAL OF UROLOGY
(2023)
Meeting Abstract
Urology & Nephrology
Ronald Kool, Gautier Marcq, Alice Dragomir, Girish Kulkarni, Rodney H. Breau, Michael Kim, Ionut Busca, Hamidreza Abdi, Mark Dawidek, Michael Uy, Gagan Fervaha, Nimira Alimohamed, Jonathan Izawa, Claudio Jeldres, Ricardo Rendon, Bobby Shayegan, Robert Siemens, Peter C. Black, Fabio L. Cury, Wassim Kassouf
JOURNAL OF UROLOGY
(2023)
Article
Oncology
Fabio L. Cury, Gustavo A. Viani, Andre G. Gouveia, Camila V. S. Freire, Gabriel de A. Grisi, Fabio Y. Moraes
Summary: In limb-sparing treatment of soft tissue sarcoma patients, a 5-day course of preoperative radiotherapy results in high local control and favorable R0 margins, with acceptable complication rates, particularly for patients receiving higher biological equivalent doses.
RADIOTHERAPY AND ONCOLOGY
(2024)
Meeting Abstract
Oncology
Sergio Faria, Marie Cuclos, Fabio Cury, Horacio Patrocinio, Luis Souhami
RADIOTHERAPY AND ONCOLOGY
(2022)
Meeting Abstract
Oncology
Sergio Faria, Marie Duclos, Mohammed Aldohan, Fabio Cury, Horacio Patrocinio, Luis Souhami
RADIOTHERAPY AND ONCOLOGY
(2022)
Article
Urology & Nephrology
Gautier Marcq, Gertruda Evaristo, Ronald Kool, Surashri Shinde-Jadhav, Rodrigo Skowronski, Luis Souhami, Fabio Cury, Fadi Brimo, Wassim Kassouf
Summary: This study evaluated the impact of PD-L1 expression on tumor and immune cells in the tumor microenvironment for patients with muscle-invasive bladder cancer treated with bladder-sparing therapy. The results showed that overexpression of PD-L1 on immune cells can predict a better response to radiation-based therapy.
EUROPEAN UROLOGY OPEN SCIENCE
(2022)
Article
Oncology
Justine G. Albert, Christopher Lo, Zeev Rosberger, Saul Frenkiel, Michael Hier, Anthony Zeitouni, Karen Kost, Alex Mlynarek, Martin Black, Christina MacDonald, Keith Richardson, Marco Mascarella, Gregoire B. Morand, Gabrielle Chartier, Nader Sadeghi, Khalil Sultanem, George Shenouda, Fabio L. Cury, Melissa Henry
Summary: This study highlighted the multifaceted nature of body image concerns in patients with head and neck cancer (HNC) and its biopsychosocial determinants. Clinicians should pay specific attention to these biopsychosocial markers in their clinics to predict high levels of body image concerns and tailor communication/refer for support accordingly.
Article
Urology & Nephrology
Ronald Kool, Gautier Marcq, Surashri Shinde-Jadhav, Jose Joao Mansure, Ramy Saleh, Raghu Rajan, Armen Aprikian, Simon Tanguay, Fabio L. Cury, Fadi Brimo, Luis Souhami, Wassim Kassouf
Summary: This study analyzed the impact of serum lymphocyte-based biomarkers on patients with MIBC treated with trimodal therapy. It found that a high pre-NLR value was associated with a lower treatment response rate and poorer survival outcomes.
EUROPEAN UROLOGY OPEN SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Priyanga Kumar, Noel Nesakumar, Jayashree Gopal, Sakthivel Sivasubramanian, Srinivasan Vedantham, John Bosco Balaguru Rayappan
Summary: This study developed an electrochemical biosensor for measuring MG levels in the plasma of type-2 diabetes mellitus patients. The biosensor showed a wide linear concentration range, high sensitivity, and a 90% correlation with ELISA data. It also exhibited a significant correlation with HbA1c and fasting plasma glucose levels.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Cristina Tortolini, Valeria Gigli, Antonio Angeloni, Federico Tasca, Nguyen T. K. Thanh, Riccarda Antiochia
Summary: The development of a novel voltammetric immunosensor for the detection of salivary MMP-8 at the point-of-care is described. The sensor showed good performance and comparable results to the conventional ELISA method when tested in real saliva samples. This biosensor is single-use, cost-effective, and requires a small quantity of test medium and a short preparation time.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Rimsha B. Jamal, Ulrich Bay Gosewinkel, Elena E. Ferapontova
Summary: Pathogen-triggered infections are a severe global threat to human health. Researchers have developed a fast and inexpensive electrocatalytic aptamer assay for the specific and ultrasensitive detection of E. coli, allowing for timely treatment and prevention. The method is fast, sensitive, and can be used in field and point-of-care applications for analysis of bacteria in the human environment.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Miao Liu, Yuwei Wang, Shanshan Tang, Wei Wang, Axin Liang, Aiqin Luo
Summary: An unlabeled ratiometric molecular imprinted electrochemiluminescence sensor was developed for the determination of trace uric acid using MXene@NaAsc, CdSe@ZnS quantum dots, and molecularly imprinted polymer composites modified glass carbon electrode. This sensor, with easy preparation, great selectivity, and excellent sensitivity, successfully detected uric acid in human serum.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Charlotte Da Silva, Camille Lamarche, Carole Pichereaux, Emmanuelle Mouton-Barbosa, Gauthier Demol, Sebastien Boisne, Etienne Dague, Odile Burlet-Schiltz, Flavien Pillet, Marie-Pierre Rols
Summary: Low-energy electron beams (LEEB) are a safe and practical sterilization solution for industrial applications. To address the limitations of LEEB, we developed a low-energy pulsed electron beam generator (LEPEB) that can effectively and efficiently eradicate bacteria in a wide range of industrial applications.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Daniel Dobrovodsky, Ales Danhel, Daniel Renciuk, Jean-Louis Mergny, Miroslav Fojta
Summary: In this study, N-methyl mesoporphyrin IX (NMM) was utilized as a voltammetric probe for the electrochemical detection of G4s. The detection of NMM was achieved by cyclic voltammetry on a hanging mercury drop electrode (HMDE) with a limit of detection (LOD) of 40 nM. The reduction signal of NMM was found to be significantly higher when G4 oligodeoxynucleotides (G4 ODNs) were present compared to single- or double-stranded ODNs or unfolded ODNs capable of forming G4s. Gradual transition from unstructured single strand to G4, induced by increasing concentrations of the G4 stabilizing K+ ions, was detected for the first time using electrochemical methods. Circular dichroism spectroscopy provided support for the obtained results. This work expands on the utilization of electrochemical probes for DNA secondary structure recognition and offers a proof of principle for the development of novel electroanalytical methods for nucleic acid structure studies.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Mengjiao Zhu, Yu Liu, Meiyue Wang, Tao Liu, Zhenyu Chu, Wanqin Jin
Summary: Early rapid diagnosis of COVID-19 is crucial for reducing the risk of severe symptoms and loss of lung function. Researchers have proposed an ultrafast and ultrasensitive DNA sensor that can accurately detect the virus in a short period of time, with outstanding selectivity.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Fatima-Zahra Ait-Itto, James A. Behan, Mathieu Martinez, Frederic Barriere
Summary: This study investigated the feasibility of using ancient marine sediments as inoculum for bioanode development in microbial fuel cells (MFC). The results showed the presence of two exoelectrogenic bacterial genera in these iron-rich sediments and confirmed that the development of the bioanode derived from the native microbiota. This study has important implications for understanding the role of these bacteria in broader paleoenvironmental phenomena.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Issa Fall, Bastien Doumeche, Sofiene Abdellaoui, Caroline Remond, Harivony Rakotoarivonina, Marjorie Ochs
Summary: This article presents a novel electrochemical tool based on lignin-coated paper electrodes for the detection and characterization of ligninolytic activity. The suitability of this method has been demonstrated using a catalaseperoxidase isolated from Thermobacillus xylanilyticus.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Chenyi Zhuo, Dehong Yu, Jiuying Cui, Zichun Song, Qianli Tang, Xianjiu Liao, Zhao Liu, Ning Xin, Lu Lou, Fenglei Gao
Summary: A label-free detection strategy for quantification of Apolipoprotein A4 (Apo-A4) has been developed based on rolling circle amplification (RCA) and proximity hybridization-induced DNAzyme-driven bipedal DNA walker. This method shows high sensitivity and selectivity for a wide range of protein targets.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Niloufar Fattahi, Jeffrey Reed, Evan Heronemus, Priyasha Fernando, Ryan Hansen, Prathap Parameswaran
Summary: In this study, polyethylene glycol hydrogels were developed as protective coatings for electroactive biofilms, improving their viability under low resource conditions and ammonia-N shocks.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Xiaopeng Hou, Qiongyi Cheng, Hui Wang
Summary: A self-cleaning paper-based microfluidic biosensor was developed using hydrophobic paper decorated with polymeric octadecyl trichlorosilane. The biosensor showed improved performance and could effectively measure the concentration of copper ions in livestock feed and manure.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Yanling Zhang, Jie Wang, Min Liu, Yun Ni, Yao Yue, Dawei He, Ruijiang Liu
Summary: An innovative electrochemical biosensor has been developed for sensitive detection of HER2 protein, an important tumor marker for breast cancer diagnosis and treatment evaluation. The biosensor utilizes specific recognition probes and nanomaterials, along with a unique sensing strategy, to achieve ultra-low detection limit and demonstrate excellent selectivity, reproducibility, and stability.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Humayun Amir, Vasanth Subramanian, Sundaram Sornambikai, Nagamony Ponpandian, Chinnusamy Viswanathan
Summary: In this study, the electrochemical detection of breast cancer biomarker HER2 was successfully achieved using the N-CQDs/GS as the detector. The BSA-modified HER2 Antibody/N-CQDs/GS immunoelectrode preserved excellent activity for the biosensor, while the GS electrode provided high stability and conductivity. The method exhibited a low detection limit and optimal specificity, stability, and reproducibility for detecting HER-2 protein in untreated blood samples from breast cancer patients.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Ilona Uzieliene, Anton Popov, Raminta Vaiciuleviciute, Gailute Kirdaite, Eiva Bernotiene, Almira Ramanaviciene
Summary: This review discusses the application of polypyrrole (Ppy), an electroconductive polymer, in cell culture experiments with electrical stimulation (ES) and its potential for tissue regeneration. Ppy can direct ES to cells and stimulate differentiation towards different cell lineages. Different types of Ppy materials and their combination with active molecules are explored.
BIOELECTROCHEMISTRY
(2024)