- Home
- Publications
- Publication Search
- Publication Details
Title
Status and Prospects of Aptamers as Drug Components
Authors
Keywords
Diabetic Macular Edema, Pegaptanib, Glycidyl Ether, Aptamer Selection, Nucleic Acid Aptamers
Journal
BIODRUGS
Volume 29, Issue 3, Pages 151-165
Publisher
Springer Nature
Online
2015-05-18
DOI
10.1007/s40259-015-0126-5
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Turning mirror-image oligonucleotides into drugs: the evolution of Spiegelmer® therapeutics
- (2015) Axel Vater et al. DRUG DISCOVERY TODAY
- Targeted delivery of anticancer drugs by aptamer AS1411 mediated Pluronic F127/cyclodextrin-linked polymer composite micelles
- (2015) Xin Li et al. Nanomedicine-Nanotechnology Biology and Medicine
- Aptamers: Active Targeting Ligands for Cancer Diagnosis and Therapy
- (2015) Xu Wu et al. Theranostics
- Nucleolin-targeting liposomes guided by aptamer AS1411 for the delivery of siRNA for the treatment of malignant melanomas
- (2014) Liyu Li et al. BIOMATERIALS
- Blocking interaction of viral gp120 and CD4-expressing T cells by single-stranded DNA aptamers
- (2014) Nianxi Zhao et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Chemically Modified DNA Aptamers Bind Interleukin-6 with High Affinity and Inhibit Signaling by Blocking Its Interaction with Interleukin-6 Receptor
- (2014) Shashi Gupta et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Current Progress of Aptamer-Based Molecular Imaging
- (2014) A. Z. Wang et al. JOURNAL OF NUCLEAR MEDICINE
- Synthetic Aptamer-Polymer Hybrid Constructs for Programmed Drug Delivery into Specific Target Cells
- (2014) Seung Soo Oh et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Aptamer-Targeted DNA Nanostructures for Therapeutic Delivery
- (2014) Phapanin Charoenphol et al. MOLECULAR PHARMACEUTICS
- Multifunctional Aptamer-miRNA Conjugates for Targeted Cancer Therapy
- (2014) Carla L Esposito et al. MOLECULAR THERAPY
- Inhibition of Receptor Signaling and of Glioblastoma-derived Tumor Growth by a Novel PDGFRβ Aptamer
- (2014) Simona Camorani et al. MOLECULAR THERAPY
- Targeted Inhibition of Prostate Cancer Metastases with an RNA Aptamer to Prostate-specific Membrane Antigen
- (2014) Justin P Dassie et al. MOLECULAR THERAPY
- A Theranostic “SMART” Aptamer for Targeted Therapy of Prostate Cancer
- (2014) Vittorio de Franciscis MOLECULAR THERAPY
- Aptamer-targeted Antigen Delivery
- (2014) Brian C Wengerter et al. MOLECULAR THERAPY
- Nanoparticles for photothermal therapies
- (2014) D. Jaque et al. Nanoscale
- Clinical development success rates for investigational drugs
- (2014) Michael Hay et al. NATURE BIOTECHNOLOGY
- RNAi Therapies: Drugging the Undruggable
- (2014) S. Y. Wu et al. Science Translational Medicine
- Smart Materials Based on DNA Aptamers: Taking Aptasensing to the Next Level
- (2014) Emily Mastronardi et al. SENSORS
- Considerations for Assessment of Reproductive and Developmental Toxicity of Oligonucleotide-Based Therapeutics
- (2014) Joy Cavagnaro et al. Nucleic Acid Therapeutics
- Inhibition of PAI-1 Antiproteolytic Activity Against tPA by RNA Aptamers
- (2014) Jared Damare et al. Nucleic Acid Therapeutics
- Recommendations for Safety Pharmacology Evaluations of Oligonucleotide-Based Therapeutics
- (2014) Cindy L. Berman et al. Nucleic Acid Therapeutics
- Aptamers as Promising Molecular Recognition Elements for Diagnostics and Therapeutics in the Central Nervous System
- (2014) Erin M. McConnell et al. Nucleic Acid Therapeutics
- Phosphorothioates, Essential Components of Therapeutic Oligonucleotides
- (2014) Fritz Eckstein Nucleic Acid Therapeutics
- DNA-Aptamer Targeting Vimentin for Tumor Therapy In Vivo
- (2014) Tatyana N. Zamay et al. Nucleic Acid Therapeutics
- DNA aptamer technology for personalized medicine
- (2014) Hang Xing et al. Current Opinion in Chemical Engineering
- Development of RNA Aptamers Targeting Ebola Virus VP35
- (2013) Jennifer M. Binning et al. BIOCHEMISTRY
- The effects of the anti-hepcidin Spiegelmer NOX-H94 on inflammation-induced anemia in cynomolgus monkeys
- (2013) F. Schwoebel et al. BLOOD
- The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization
- (2013) J. Hoellenriegel et al. BLOOD
- A Decade of Riboswitches
- (2013) Alexander Serganov et al. CELL
- Smart ligand: Aptamer-mediated targeted delivery of chemotherapeutic drugs and siRNA for cancer therapy
- (2013) Xin Li et al. JOURNAL OF CONTROLLED RELEASE
- Aptamers: multifunctional molecules for biomedical research
- (2013) Jayeeta Banerjee et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Inhibition of Hepatitis C Virus (HCV) Replication by Specific RNA Aptamers against HCV NS5B RNA Replicase
- (2013) C. H. Lee et al. JOURNAL OF VIROLOGY
- Nucleolin Targeting AS1411 Modified Protein Nanoparticle for Antitumor Drugs Delivery
- (2013) Jinhui Wu et al. MOLECULAR PHARMACEUTICS
- Periostin-binding DNA Aptamer Inhibits Breast Cancer Growth and Metastasis
- (2013) Yu Jin Lee et al. MOLECULAR THERAPY
- A Novel C5a-neutralizing Mirror-image (l-)Aptamer Prevents Organ Failure and Improves Survival in Experimental Sepsis
- (2013) Kai Hoehlig et al. MOLECULAR THERAPY
- Regado's aptamer lines up against anticoagulants
- (2013) Gunjan Sinha NATURE BIOTECHNOLOGY
- Aptamers as Theranostic Agents: Modifications, Serum Stability and Functionalisation
- (2013) Sarah Shigdar et al. SENSORS
- Photosensitizer-Gold Nanorod Composite for Targeted Multimodal Therapy
- (2013) Jian Wang et al. Small
- Therapies for Neovascular Age-Related Macular Degeneration: Current Approaches and Pharmacologic Agents in Development
- (2013) Mostafa Hanout et al. Biomed Research International
- CD28 Aptamers as Powerful Immune Response Modulators
- (2013) Fernando Pastor et al. Molecular Therapy-Nucleic Acids
- In vivo SELEX for Identification of Brain-penetrating Aptamers
- (2013) Congsheng Cheng et al. Molecular Therapy-Nucleic Acids
- Interleukin-6 signaling pathway in targeted therapy for cancer
- (2012) Yuqi Guo et al. CANCER TREATMENT REVIEWS
- Therapeutic RNA aptamers in clinical trials
- (2012) Padma Sundaram et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Generating Aptamers by Cell-SELEX for Applications in Molecular Medicine
- (2012) Mao Ye et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Functional In Vivo Delivery of Multiplexed Anti-HIV-1 siRNAs via a Chemically Synthesized Aptamer With a Sticky Bridge
- (2012) Jiehua Zhou et al. MOLECULAR THERAPY
- Delivery of chemo-sensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers
- (2012) Kristina W. Thiel et al. NUCLEIC ACIDS RESEARCH
- Development of Novel Single-Stranded Nucleic Acid Aptamers against the Pro-Angiogenic and Metastatic Enzyme Heparanase (HPSE1)
- (2012) Suzanne C. Simmons et al. PLoS One
- Interleukin-6: from an inflammatory marker to a target for inflammatory diseases
- (2012) Mercedes Rincon TRENDS IN IMMUNOLOGY
- Dressed for success – applying chemistry to modulate aptamer functionality
- (2012) Fabian Tolle et al. Chemical Science
- Vimentin in cancer and its potential as a molecular target for cancer therapy
- (2011) Arun Satelli et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Nucleic Acid Aptamers: Clinical Applications and Promising New Horizons
- (2011) X. Ni et al. CURRENT MEDICINAL CHEMISTRY
- Prognostic and Clinicopathologic Associations of OncogenicBRAFin Metastatic Melanoma
- (2011) Georgina V. Long et al. JOURNAL OF CLINICAL ONCOLOGY
- Engineering Polymeric Aptamers for Selective Cytotoxicity
- (2011) Liu Yang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Challenges and opportunities for structural DNA nanotechnology
- (2011) Andre V. Pinheiro et al. Nature Nanotechnology
- Aptamer-Based Multiplexed Proteomic Technology for Biomarker Discovery
- (2011) Larry Gold et al. PLoS One
- Intra-Accumbens Injection of a Dopamine Aptamer Abates MK-801-Induced Cognitive Dysfunction in a Model of Schizophrenia
- (2011) Matthew R. Holahan et al. PLoS One
- From SOMAmer-Based Biomarker Discovery to Diagnostic and Clinical Applications: A SOMAmer-Based, Streamlined Multiplex Proteomic Assay
- (2011) Stephan Kraemer et al. PLoS One
- Molecular aptamers for drug delivery
- (2011) Weihong Tan et al. TRENDS IN BIOTECHNOLOGY
- The immunogenicity of humanized and fully human antibodies
- (2010) Fiona A. Harding et al. mAbs
- Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips
- (2010) Sriram Kosuri et al. NATURE BIOTECHNOLOGY
- Aptamers as therapeutics
- (2010) Anthony D. Keefe et al. NATURE REVIEWS DRUG DISCOVERY
- The Path to Personalized Medicine
- (2010) Margaret A. Hamburg et al. NEW ENGLAND JOURNAL OF MEDICINE
- Selecting RNA aptamers for synthetic biology: investigating magnesium dependence and predicting binding affinity
- (2010) James M. Carothers et al. NUCLEIC ACIDS RESEARCH
- A Reversible Aptamer Improves Outcome and Safety in Murine Models of Stroke and Hemorrhage
- (2010) Charlene M. Blake et al. OLIGONUCLEOTIDES
- A randomised pilot trial of the anti-von Willebrand factor aptamer ARC1779 in patients with type 2b von Willebrand disease
- (2010) Petra Paulinska et al. THROMBOSIS AND HAEMOSTASIS
- The Chemical Biology of Aptamers
- (2009) Günter Mayer ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Complement and its role in innate and adaptive immune responses
- (2009) Jason R Dunkelberger et al. CELL RESEARCH
- Disease-specific biomarker discovery by aptamers
- (2009) Henning Ulrich et al. CYTOMETRY PART A
- Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer
- (2009) Paula J. Bates et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Development of universal antidotes to control aptamer activity
- (2009) Sabah Oney et al. NATURE MEDICINE
- Aptamers selected against the unglycosylated EGFRvIII ectodomain and delivered intracellularly reduce membrane-bound EGFRvIII and induce apoptosis
- (2008) Yingmiao Liu et al. BIOLOGICAL CHEMISTRY
- Humanization of an Anti-CD34 Monoclonal Antibody by Complementarity-determining Region Grafting Based on Computer-assisted Molecular Modelling
- (2008) Sheng Hou et al. JOURNAL OF BIOCHEMISTRY
- Aptamer-Facilitated Biomarker Discovery (AptaBiD)
- (2008) Maxim V. Berezovski et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started