Article
Health Care Sciences & Services
Ilias P. Nikas, Svenja Seide, Tanja Proctor, Zoi Kleinaki, Maria Kleinaki, Jordan P. Reynolds
Summary: The Paris System is a standardized reporting system for urinary cytology that provides diagnostic accuracy by assigning samples into seven diagnostic categories and calculating the risk of high-grade malignancy. It guides clinical management and has an overall good diagnostic performance.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Oncology
Yu-Liang Liu, Chun-Te Wu, Yu-Chao Hsu, Miao-Fen Chen, Chih-Shou Chen, Chung-Sheng Shi, Yun-Ching Huang
Summary: Urothelial carcinoma (UC) is the most common malignancy in dialysis patients in Taiwan, and radical cystectomy is the standard treatment for muscle-invasive bladder cancer. However, dialysis patients undergoing radical cystectomy have a higher risk of complications and mortality. In this study, we found that accurate reporting of complications is important for counseling and risk assessment. We also identified high comorbidity and low-volume surgeons as significant risk factors for major complications. Additionally, male sex, older age, and major complications were found to significantly influence overall survival.
Article
Biophysics
Melanie MacGregor, Hanieh Safizadeh Shirazi, Kit Man Chan, Kola Ostrikov, Kym McNicholas, Alex Jay, Michael Chong, Alexander H. Staudacher, Thomas D. Michl, Aigerim Zhalgasbaikyzy, Michael P. Brown, Moein Navvab Kashani, Adam Di Fiore, Alex Grochowski, Stephen Robb, Simon Belcher, Jordan Li, Jonathan M. Gleadle, Krasimir Vasilev
Summary: The non-invasive diagnostic platform presented in this study combines microfluidic technology with PDD principles and immunocapture technology to detect shed bladder cancer cells in patient urine, achieving highly specific capture rates. In a pilot study, it successfully differentiated bladder cancer patients from non-cancer controls, showing potential for post-treatment surveillance and cancer detection in suspected bladder cancer patients.
BIOSENSORS & BIOELECTRONICS
(2021)
Review
Endocrinology & Metabolism
Viral N. Shah, Satish K. Garg
Summary: The study discusses the benefits of the HCL system in improving glycemic control and reducing hypoglycemia, highlighting the importance of standardized reporting for easy interpretation of data. It introduces the concept of an artificial pancreas (AP) Dashboard with seven components to aid providers and patients in understanding HCL data and improving glycemic outcomes.
DIABETES TECHNOLOGY & THERAPEUTICS
(2021)
Article
Endocrinology & Metabolism
Syed Z. Ali, Zubair W. Baloch, Beatrix Cochand-Priollet, Fernando C. Schmitt, Philippe Vielh, Paul A. VanderLaan
Summary: Since its first edition in 2010, The Bethesda System for Reporting Thyroid Cytopathology has provided a standardized reporting system for thyroid fine needle aspirations. The third edition offers key updates, including a single name for each diagnostic category, updated risk of malignancy data, and additional discussion on pediatric thyroid disease and molecular testing. The nomenclature has been aligned with the 2022 World Health Organization Classification of Thyroid Neoplasms, and new chapters on molecular testing and clinical perspectives have been added.
Article
Radiology, Nuclear Medicine & Medical Imaging
Xiaoyan Meng, Henglong Hu, Yanchun Wang, Cui Feng, Daoyu Hu, Zheng Liu, Ihab R. Kamel, Zhen Li
Summary: This study aimed to describe the characteristics of cases with discordant T2-weighted imaging and diffusion-weighted imaging scores in patients with bladder cancer, and verify the accuracy of the VI-RADS scoring system and the necessity of dynamic contrast-enhanced sequence. The results showed that DCE was crucial in the discordant group for evaluating muscle-invasiveness, while DCE may not be necessary for the concordant group.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Review
Computer Science, Information Systems
Orna Fennelly, Loretto Grogan, Angela Reed, Nicholas R. Hardiker
Summary: The study explored the use and impact of standardized terminologies within nursing and midwifery practice across 25 different countries and identified that the impact of STs on practice depended on various factors such as healthcare setting, patient cohort, nursing experience, provision of education and support in using the ST, and usability of EHRs.
INTERNATIONAL JOURNAL OF MEDICAL INFORMATICS
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Fabian H. J. Elsholtz, Patrick Asbach, Matthias Haas, Minerva Becker, Regina G. H. Beets-Tan, Harriet C. Thoeny, Anwar R. Padhani, Bernd Hamm
Summary: Node-RADS is a new imaging assessment system that systematically classifies the degree of suspicion of lymph node involvement based on established imaging findings. It improves communication with referring physicians and promotes consistency in reporting for primary staging and response assessment.
EUROPEAN RADIOLOGY
(2021)
Article
Health Care Sciences & Services
Mohammad Ali Khaleel, Amer Hayat Khan, Siti Maisharah Sheikh Ghadzi, Azreen Syazril Adnan, Qasem M. Abdallah
Summary: FAERS is one of the largest spontaneous adverse events reporting databases in the world, but analyzing its data presents many challenges. This study provides a processed and deduplicated dataset from the FAERS database, with standardized and normalized drug names. Additionally, pre-calculated disproportionate analysis is included for each drug-adverse event pair in the database.
Article
Biochemistry & Molecular Biology
Mandy Berndt-Paetz, Shanfu Han, Annett Weimann, Annabell Reinhold, Sandra Nuernberger, Jochen Neuhaus
Summary: Three-dimensional tumor models, such as organoids, are valuable tools for bladder cancer research as they accurately mimic the structure and characteristics of solid tumors. These models can be used for functional studies and development of anti-cancer drugs.
Article
Cell Biology
Simon Walz, Paul Pollehne, Ruizhi Geng, Johannes Schneider, Moritz Maas, Wilhelm K. Aicher, Arnulf Stenzl, Bastian Amend, Niklas Harland
Summary: This study explores the potential of establishing urine-derived tumor organoids from bladder cancer patients as an alternative to tissue-derived organoids. The researchers successfully cultured urine-derived BC organoids from 83% of the specimens investigated, with comparable efficiency to tissue-derived organoids. These urine-derived BC organoids showed similar expressions of BC markers compared to the parental tumor, suggesting their potential as a non-invasive tool for studying BC and evaluating therapeutic responses.
Article
Oncology
Julian Hermans, Friedrich Jokisch, Yannic Volz, Lennert Eismann, Paulo Pfitzinger, Benedikt Ebner, Philipp Weinhold, Boris Schlenker, Christian G. Stief, Stefan Tritschler, Gerald B. Schulz
Summary: BCG therapy has a short-term adverse impact on the efficacy of urinary cytology. Cases classified as suspicious for high-grade urothelial carcinoma after BCG therapy should be considered positive, and patients with false-positive cytology findings should be closely monitored.
CANCER CYTOPATHOLOGY
(2022)
Article
Pathology
Francesco Pierconti, Maurizio Martini, Tonia Cenci, Vincenzo Fiorentino, Emilio Sacco, Riccardo Bientinesi, Dario Pugliese, Roberto Iacovelli, Giovanni Schinzari, Luigi Maria Larocca, Pier Francesco Bassi
Summary: The study analyzed the combination of Bladder EpiCheck with cytology and found that in different cytological categories, the sensitivity, specificity, Positive Predictive Value (PPV), and Negative Predictive Value (NPV) of Bladder EpiCheck were higher in the High-grade Urothelial Carcinoma (HGUC) category compared to the Suspicious for High-grade Urothelial Carcinoma (SHGUC) group. This suggests that molecular signatures of different TPS cytological categories vary and that SHGUC and HGUC should be considered distinct entities in TPS.
JOURNAL OF CLINICAL PATHOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Natalia Gruba, Lech Stachurski, Adam Lesner
Summary: Bladder cancer is a common cancer with high recurrence rate and poor prognosis, usually asymptomatic and requiring invasive and expensive regular re-examinations. The study used chromogenic substrates for qualitative determination of urine enzyme activity in healthy individuals and bladder cancer patients, finding proteolytic activity in cancer patients but not in healthy volunteers.
CHEMISTRY & BIODIVERSITY
(2021)
Article
Computer Science, Information Systems
Robin R. Austin, Sripriya Rajamani, Ratchada Jantraporn, Anna Pirsch, Karen S. Martin
Summary: The study examined standardized consumer-generated social determinants of health (SDOH) data and resilience using the MyStrengths+MyHealth app that was built using the Omaha System. The analysis of data from 919 participants showed an average of 11 strengths, 21 challenges, and 15 needs. Participants with at least one income challenge had fewer strengths, more challenges, and more needs compared to those without an income challenge. This standards-based approach provides an opportunity to understand whole-person health and address health inequities.
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION
(2023)
Article
Medical Laboratory Technology
Barbara A. Crothers, Mohiedean Ghofrani, Chengquan Zhao, Leslie G. Dodd, Kelly Goodrich, Mujtaba Husain, Daniel F. Kurtycz, Donna K. Russell, Rulong Z. Shen, Rhona J. Souers, Paul N. Staats, Z. Laura Tabatabai, Benjamin L. Witt, Diane Davis Davey
ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
(2019)
Article
Medical Laboratory Technology
Kaitlin E. Sundling, Daniel F. I. Kurtycz
DIAGNOSTIC CYTOPATHOLOGY
(2019)
Review
Pathology
Andrew S. Field, Wendy A. Raymond, Mary Rickard, Lauren Arnold, Elena F. Brachtel, Benjaporn Chaiwun, Lan Chen, Luigi Di Bonito, Daniel F. I. Kurtycz, Andrew H. S. Lee, Elgene Lim, Britt-Marie Ljung, Pamela Michelow, Robert Y. Osamura, Maurizio Pinamonti, Torill Sauer, Davendra Segara, Gary Tse, Philippe Vielh, Phek Y. Chong, Fernando Schmitt
Article
Medical Laboratory Technology
Guliz A. Barkan, Z. Laura Tabatabai, Daniel F. Kurtycz, Vijayalakshmi Padmanabhan, Rhona J. Souers, Ritu Nayar, Charles D. Sturgis
ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
(2020)
Article
Medical Laboratory Technology
Paul N. Staats, Rhona J. Souers, Amberly Lindau Nunez, Zaibo Li, Daniel F. I. Kurtycz, Kelly Goodrich, Benjamin Lloyd Witt, Diane Davis Davey, Christine Noga Booth
ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
(2020)
Article
Medical Laboratory Technology
Daniel F. I. Kurtycz, Kaitlin E. Sundling, Guliz A. Barkan
DIAGNOSTIC CYTOPATHOLOGY
(2020)
Article
Oncology
Andrew S. Field, Daniel F. I. Kurtycz, Wendy A. Raymond, Fernando Schmitt
Summary: A group of international experts drafted a comprehensive system for reporting breast fine needle aspiration biopsy cytopathology, and conducted a web-based survey to assess international response. The survey results provided insights into the current role and use of breast FNAB globally, strongly supporting the development of the IAC Yokohama System.
CANCER CYTOPATHOLOGY
(2021)
Editorial Material
Oncology
Daniel F. Kurtycz
CANCER CYTOPATHOLOGY
(2022)
Article
Medical Laboratory Technology
Benjamin L. Witt, Wenhua Zhou, Abiy B. Ambaye, Andrew Bellizzi, Christine N. Booth, Kaitlin Sundling, Lananh Nguyen, Donna K. Russell, Malcolm Schinstine, Paul N. Staats, Jean Thomsen, Megan Troxell, Rhona J. Souers, James Dvorak, Xiaoqi Lin, Daniel F. I. Kurtycz
Summary: The study demonstrates the importance of using cell lines with known antigenicity to identify variability between laboratories in immunohistochemistry testing. This validation method can help improve the accuracy and reliability of the tests.
ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
(2023)
Article
Cell Biology
Christopher J. VandenBussche, Barbara Crothers, Ashish Chandra, Fernando Schmitt, Daniel F. I. Kurtycz
Summary: Objective: An international panel conducted a survey to identify opinions and explore existing practice patterns regarding body fluid cytopathology. The survey collected 593 international participant responses, revealing strong support for the development of a unified system for reporting body fluid cytopathology among respondents.
Review
Oncology
Esther Diana Rossi, Zubair Baloch, Guliz Barkan, Maria Pia Foschini, Daniel Kurtycz, Marc Pusztaszeri, Philippe Vielh, William C. Faquin
Summary: The use of standardized reporting systems for non-gynecologic cytopathology, including the Milan System for Reporting Salivary Gland Cytopathology (MSRSGC), has gained popularity in the past decade. The MSRSGC defines diagnostic categories and provides risk assessment and management algorithms for salivary gland lesions. The second edition of MSRSGC, published in 2023, includes refined risks of malignancy, updates in ancillary testing, and a guide to the practical application of the latest ancillary markers.
CANCER CYTOPATHOLOGY
(2023)
Review
Cell Biology
Esther Diana Rossi, Zubair Baloch, Guliz Barkan, Maria Pia Foschini, Daniel Kurtycz, Marc Pusztaszeri, Philippe Vielh, William C. Faquin
Summary: The use of standardised reporting systems for non-gynaecologic cytopathology has gained popularity in various areas, including thyroid fine-needle aspiration and urine cytology. The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) provides a defined risk assessment and clinical management algorithm for diagnosing salivary gland lesions. The MSRSGC has been widely accepted and its second edition includes updated risk assessments and advancements in imaging and ancillary testing.
Article
Oncology
Esther Diana Rossi, William C. Faquin, Zubair Baloch, Guliz A. Barkan, Maria Pia Foschini, Marc Pusztaszeri, Philippe Vielh, Daniel F. I. Kurtycz
CANCER CYTOPATHOLOGY
(2017)
Article
Medical Laboratory Technology
Vijayalakshmi Padmanabhan, Carrie B. Marshall, Guliz Akdas Barkan, Mohiedean Ghofrani, Alice Laser, Idris Tolgay Ocal, Charles David Sturgis, Rhona Souers, Daniel F. I. Kurtycz
DIAGNOSTIC CYTOPATHOLOGY
(2017)
Meeting Abstract
Pathology
Vijayalakshmi i Padmanabhan, Carrie B. Marshall, Guliz A. Barkan, Mohiedean Ghofrani, Idris T. Ocal, Charles D. Sturgis, Rhona J. Souers, Daniel F. I. Kurtycz