PGMA-Based Star-Like Polycations with Plentiful Hydroxyl Groups Act as Highly Efficient miRNA Delivery Nanovectors for Effective Applications in Heart Diseases

Acid-Labile Poly(glycidyl methacrylate)-Based Star Gene Vectors

(2015) Yan-Yu Yang et al.   ACS Applied Materials & Interfaces

PGMA-based starlike polycations with flanking phenylboronic acid groups for highly efficient multifunctional gene delivery systems

(2015) Rui-Quan Li et al.   Polymer Chemistry

Redox-Triggered Gatekeeper-Enveloped Starlike Hollow Silica Nanoparticles for Intelligent Delivery Systems

(2015) Nana Zhao et al.   Small

Exosome-delivered microRNAs modulate the inflammatory response to endotoxin

(2015) Margaret Alexander et al.   Nature Communications

Gd(III) ion-chelated supramolecular assemblies composed of PGMA-based polycations for effective biomedical applications

(2015) Yu Zhao et al.   NPG Asia Materials

microRNA-29b prevents liver fibrosis by attenuating hepatic stellate cell activation and inducing apoptosis through targeting PI3K/AKT pathway

(2015) Jia Wang et al.   Oncotarget

Ultrasmall Gold Nanoparticles as Carriers for Nucleus-Based Gene Therapy Due to Size-Dependent Nuclear Entry

(2014) Shuaidong Huo et al.   ACS Nano

A biocleavable pullulan-based vector via ATRP for liver cell-targeting gene delivery

(2014) Xin-Chao Yang et al.   BIOMATERIALS

S100a8/a9 Released by CD11b + Gr1 + Neutrophils Activates Cardiac Fibroblasts to Initiate Angiotensin II–Induced Cardiac Inflammation and Injury

(2014) Yina Wu et al.   HYPERTENSION

A Collagen-based Scaffold Delivering Exogenous MicroRNA-29B to Modulate Extracellular Matrix Remodeling

(2014) Michael Monaghan et al.   MOLECULAR THERAPY

Efficient Pro-survival/angiogenic miRNA Delivery by an MRI-Detectable Nanomaterial

(2013) Renata S. M. Gomes et al.   ACS Nano

Non-Viral Gene Delivery via Membrane-Penetrating, Mannose-Targeting Supramolecular Self-Assembled Nanocomplexes

(2013) Lichen Yin et al.   ADVANCED MATERIALS

Dual Responsive, Stabilized Nanoparticles for Efficient In Vivo Plasmid Delivery

(2013) Hua Wei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fibronectin contributes to pathological cardiac hypertrophy but not physiological growth

(2013) Mathias H. Konstandin et al.   BASIC RESEARCH IN CARDIOLOGY

MicroRNA-29 family, a crucial therapeutic target for fibrosis diseases

(2013) Yong He et al.   BIOCHIMIE

Supramolecular Host–Guest Pseudocomb Conjugates Composed of Multiple Star Polycations Tied Tunably with a Linear Polycation Backbone for Gene Transfection

(2013) Y. Hu et al.   BIOCONJUGATE CHEMISTRY

Folic Acid Modified Cationic γ-Cyclodextrin-oligoethylenimine Star Polymer with Bioreducible Disulfide Linker for Efficient Targeted Gene Delivery

(2013) Feng Zhao et al.   BIOMACROMOLECULES

Linear polycations by ring-opening polymerization as non-viral gene delivery vectors

(2013) Qin-Fang Zhang et al.   BIOMATERIALS

Progress in microRNA delivery

(2013) Yu Zhang et al.   JOURNAL OF CONTROLLED RELEASE

Circulating miR-29a, Among Other Up-Regulated MicroRNAs, Is the Only Biomarker for Both Hypertrophy and Fibrosis in Patients With Hypertrophic Cardiomyopathy

(2013) Roberta Roncarati et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Nanoparticles for Gene Delivery

(2013) Huayu Tian et al.   Small

Therapeutic Delivery of MicroRNA-29b by Cationic Lipoplexes for Lung Cancer

(2013) Yun Wu et al.   Molecular Therapy-Nucleic Acids

Components Simulation of Viral Envelope via Amino Acid Modified Chitosans for Efficient Nucleic Acid Delivery: In Vitro and In Vivo Study

(2012) Jing Chang et al.   ADVANCED FUNCTIONAL MATERIALS

An Amphiphilic Dendrimer for Effective Delivery of Small Interfering RNA and Gene Silencing In Vitro and In Vivo

(2012) Tianzhu Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Interleukin-12p35 Deletion Promotes CD4 T-Cell–Dependent Macrophage Differentiation and Enhances Angiotensin II–Induced Cardiac Fibrosis

(2012) Yulin Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MicroRNAs and fibrosis

(2012) Vishal Patel et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Discovering the first microRNA-targeted drug

(2012) Morten Lindow et al.   JOURNAL OF CELL BIOLOGY

In Vivo Gene Delivery by Nonviral Vectors: Overcoming Hurdles?

(2012) Yuan Zhang et al.   MOLECULAR THERAPY

miR-29 Inhibits Bleomycin-induced Pulmonary Fibrosis in Mice

(2012) Jun Xiao et al.   MOLECULAR THERAPY

A ferroelectric memristor

(2012) André Chanthbouala et al.   NATURE MATERIALS

Inhibition of miR-29 by TGF-beta-Smad3 Signaling through Dual Mechanisms Promotes Transdifferentiation of Mouse Myoblasts into Myofibroblasts

(2012) Liang Zhou et al.   PLoS One

miRNA regulatory variation in human evolution

(2012) Jingjing Li et al.   TRENDS IN GENETICS

Advanced Materials for Co-Delivery of Drugs and Genes in Cancer Therapy

(2012) Majad Khan et al.   Advanced Healthcare Materials

A strategy to improve serum-tolerant transfection activity of polycation vectors by surface hydroxylation

(2011) Xiao-hua Luo et al.   BIOMATERIALS

Effects of hydrophobic and hydrophilic modifications on gene delivery of amphiphilic chitosan based nanocarriers

(2011) Bingqing Wang et al.   BIOMATERIALS

TGF- /Smad3 Signaling Promotes Renal Fibrosis by Inhibiting miR-29

(2011) W. Qin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Pervasive roles of microRNAs in cardiovascular biology

(2011) Eric M. Small et al.   NATURE

Biodegradable poly(amine-co-ester) terpolymers for targeted gene delivery

(2011) Jiangbing Zhou et al.   NATURE MATERIALS

Charged for success

(2011) Enrico Mastrobattista et al.   NATURE MATERIALS

High-Strength Hydrogels with Integrated Functions of H-bonding and Thermoresponsive Surface-Mediated Reverse Transfection and Cell Detachment

(2010) Lei Tang et al.   ADVANCED MATERIALS

Well-Defined Poly(2-hydroxyl-3-(2-hydroxyethylamino)propyl methacrylate) Vectors with Low Toxicity and High Gene Transfection Efficiency

(2010) F. J. Xu et al.   BIOMACROMOLECULES

Angiotensin II revisited: new roles in inflammation, immunology and aging

(2010) Ariela Benigni et al.   EMBO Molecular Medicine

Reduction-sensitive polymers and bioconjugates for biomedical applications

(2009) Fenghua Meng et al.   BIOMATERIALS

Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model

(2009) Janaiah Kota et al.   CELL

A Reinnervating MicroRNA

(2009) R. H. Brown   SCIENCE