Progress in Corneal Stromal Repair: From Tissue Grafts and Biomaterials to Modular Supramolecular Tissue-Like Assemblies

Corneal Tissue Engineering: Recent Advances and Future Perspectives

(2015) Chiara E. Ghezzi et al.   TISSUE ENGINEERING PART B-REVIEWS

An Immunocompetent, Orthotopic Mouse Model of Epithelial Ovarian Cancer Utilizing Tissue Engineered Tumor Cell Sheets

(2015) Ayumi Arauchi et al.   TISSUE ENGINEERING PART C-METHODS

Accelerated Development of Supramolecular Corneal Stromal-Like Assemblies from Corneal Fibroblasts in the Presence of Macromolecular Crowders

(2015) Pramod Kumar et al.   TISSUE ENGINEERING PART C-METHODS

Macromolecularly crowded in vitro microenvironments accelerate the production of extracellular matrix-rich supramolecular assemblies

(2015) Pramod Kumar et al.   Scientific Reports

Regeneration of corneal epithelium utilizing a collagen vitrigel membrane in rabbit models for corneal stromal wound and limbal stem cell deficiency

(2014) J. Jeremy Chae et al.   ACTA OPHTHALMOLOGICA

Macromolecular Crowding Meets Tissue Engineering by Self-Assembly: A Paradigm Shift in Regenerative Medicine

(2014) Abhigyan Satyam et al.   ADVANCED MATERIALS

Vitrified collagen-based conjunctival equivalent for ocular surface reconstruction

(2014) Huifang Zhou et al.   BIOMATERIALS

Corneal stromal bioequivalents secreted on patterned silk substrates

(2014) Jian Wu et al.   BIOMATERIALS

Combining cell sheet technology and electrospun scaffolding for engineered tubular, aligned, and contractile blood vessels

(2014) Shahrzad Rayatpisheh et al.   BIOMATERIALS

Effect of acacia honey on cultured rabbit corneal keratocytes

(2014) Choy Ker-Woon et al.   BMC CELL BIOLOGY

Long-Term Safety and Efficacy of High-Fluence Collagen Crosslinking of the Vehicle Cornea in Boston Keratoprosthesis Type 1

(2014) Anastasios J. Kanellopoulos et al.   CORNEA

Corneal stromal stem cells versus corneal fibroblasts in generating structurally appropriate corneal stromal tissue

(2014) Jian Wu et al.   EXPERIMENTAL EYE RESEARCH

Collagen Cross-Linking of the Boston Keratoprosthesis Donor Carrier to Prevent Corneal Melting in High-Risk Patients

(2014) Marie-Claude Robert et al.   Eye & Contact Lens-Science and Clinical Practice

Application of a Collagen-Based Membrane and Chondroitin Sulfate-Based Hydrogel Adhesive for the Potential Repair of Severe Ocular Surface Injuries

(2014) Jemin J. Chae et al.   MILITARY MEDICINE

A Role for Topographic Cues in the Organization of Collagenous Matrix by Corneal Fibroblasts and Stem Cells

(2014) Dimitrios Karamichos et al.   PLoS One

Keratocytes Derived from Spheroid Culture of Corneal Stromal Cells Resemble Tissue Resident Keratocytes

(2014) Yong-Soo Byun et al.   PLoS One

Human iPS cell-engineered cardiac tissue sheets with cardiomyocytes and vascular cells for cardiac regeneration

(2014) Hidetoshi Masumoto et al.   Scientific Reports

A Review of Corneal Melting after Boston Keratoprosthesis

(2014) Marie-Claude Robert et al.   Seminars in Ophthalmology

Biodegradable and Biocompatible Poly(Ethylene Glycol)-based Hydrogel Films for the Regeneration of Corneal Endothelium

(2014) Berkay Ozcelik et al.   Advanced Healthcare Materials

The bioactivity of composite Fmoc-RGDS-collagen gels

(2014) Ricardo M. Gouveia et al.   Biomaterials Science

Ultrathin chitosan–poly(ethylene glycol) hydrogel films for corneal tissue engineering

(2013) Berkay Ozcelik et al.   Acta Biomaterialia

Crosslinked collagen hydrogels as corneal implants: Effects of sterically bulky vs. non-bulky carbodiimides as crosslinkers

(2013) Jae-Il Ahn et al.   Acta Biomaterialia

Efficient Cell and Cell-Sheet Harvesting Based on Smart Surfaces Coated with a Multifunctional and Self-Organizing Elastin-Like Recombinamer

(2013) María Pierna et al.   BIOMACROMOLECULES

Modulation of keratocyte phenotype by collagen fibril nanoarchitecture in membranes for corneal repair

(2013) Qiongyu Guo et al.   BIOMATERIALS

The use of anisotropic cell sheets to control orientation during the self-organization of 3D muscle tissue

(2013) Hironobu Takahashi et al.   BIOMATERIALS

Stable corneal regeneration four years after implantation of a cell-free recombinant human collagen scaffold

(2013) Per Fagerholm et al.   BIOMATERIALS

Automatic fabrication of 3-dimensional tissues using cell sheet manipulator technique

(2013) Tetsutaro Kikuchi et al.   BIOMATERIALS

Characterization of Vitamin C-Induced Cell Sheets Formed from Primary and Immortalized Human Corneal Stromal Cells for Tissue Engineering Applications

(2013) Gesa Maria Grobe et al.   CELLS TISSUES ORGANS

Long-Term Results of Amniotic Membrane Transplantation for Partial Limbal Deficiency

(2013) Kenji Konomi et al.   CORNEA

Engineering in vitro microenvironments for cell based therapies and drug discovery

(2013) Daniela Cigognini et al.   DRUG DISCOVERY TODAY

Substrate elasticity as biomechanical modulator of tissue homeostatic parameters in corneal keratinocytes

(2013) Katharina Moers et al.   EXPERIMENTAL CELL RESEARCH

Corneal Transplantation and Immune Privilege

(2013) Jerry Y. Niederkorn   INTERNATIONAL REVIEWS OF IMMUNOLOGY

In vivostudy of the biocompatibility of a novel compressed collagen hydrogel scaffold for artificial corneas

(2013) Xianghua Xiao et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Transplantation of cancerous cell sheets effectively generates tumour-bearing model mice

(2013) Jun Akimoto et al.   Journal of Tissue Engineering and Regenerative Medicine

Human Corneal Anatomy Redefined

(2013) Harminder S. Dua et al.   OPHTHALMOLOGY

Differentiation of Human Embryonic Stem Cells into Cells with Corneal Keratocyte Phenotype

(2013) Audrey A. Chan et al.   PLoS One

Three-Dimensional Cell Culture Environment Promotes Partial Recovery of the Native Corneal Keratocyte Phenotype from a Subcultured Population

(2013) Russell E. Thompson et al.   TISSUE ENGINEERING PART A

Bioengineering Organized, Multilamellar Human Corneal Stromal Tissue by Growth Factor Supplementation on Highly Aligned Synthetic Substrates

(2013) Jian Wu et al.   TISSUE ENGINEERING PART A

Corneal Stromal Cell Plasticity: In Vitro Regulation of Cell Phenotype Through Cell-Cell Interactions in a Three-Dimensional Model

(2013) Samantha L. Wilson et al.   TISSUE ENGINEERING PART A

Macromolecular Crowding Amplifies Adipogenesis of Human Bone Marrow-Derived Mesenchymal Stem Cells by Enhancing the Pro-Adipogenic Microenvironment

(2013) Xiu Min Ang et al.   TISSUE ENGINEERING PART A

In Vitro Engineering of Vascularized Tissue Surrogates

(2013) Katsuhisa Sakaguchi et al.   Scientific Reports

Chemical and Topographical Effects on Cell Differentiation and Matrix Elasticity in a Corneal Stromal Layer Model

(2012) Samantha L. Wilson et al.   ADVANCED FUNCTIONAL MATERIALS

Adipose-Derived Stem Cells on Hyaluronic Acid–Derived Scaffold

(2012) Ladan Espandar   ARCHIVES OF OPHTHALMOLOGY

Corneal repair by human corneal keratocyte-reprogrammed iPSCs and amphiphatic carboxymethyl-hexanoyl chitosan hydrogel

(2012) Yueh Chien et al.   BIOMATERIALS

Structure and properties of collagen vitrigel membranes for ocular repair and regeneration applications

(2012) Xiomara Calderón-Colón et al.   BIOMATERIALS

Sealing and Healing of Clear Corneal Incisions with an Improved Dextran Aldehyde-PEG Amine Tissue Adhesive

(2012) H. Keith Chenault et al.   CURRENT EYE RESEARCH

Human mesenchymal stem cells differentiate into keratocyte-like cells in keratocyte-conditioned medium

(2012) Soo Hyun Park et al.   EXPERIMENTAL EYE RESEARCH

Synthesis and characterization of a novel thermoresponsive copolymer series and their application in cell and cell sheet regeneration

(2012) Maria E. Nash et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Straightforward, One-Step Fabrication of Ultrathin Thermoresponsive Films from Commercially Available pNIPAm for Cell Culture and Recovery

(2011) Maria E. Nash et al.   ACS Applied Materials & Interfaces

Synthesis and Characterization of Dendron Cross-Linked PEG Hydrogels as Corneal Adhesives

(2011) Abigail M. Oelker et al.   BIOMACROMOLECULES

Stacking of aligned cell sheets for layer-by-layer control of complex tissue structure

(2011) Corin Williams et al.   BIOMATERIALS

Anisotropic cell sheets for constructing three-dimensional tissue with well-organized cell orientation

(2011) Hironobu Takahashi et al.   BIOMATERIALS

The engineering of organized human corneal tissue through the spatial guidance of corneal stromal stem cells

(2011) Jian Wu et al.   BIOMATERIALS

Effects of edible bird's nest (EBN) on cultured rabbit corneal keratocytes

(2011) Fadhilah Zainal Abidin et al.   BMC Complementary and Alternative Medicine

Human Corneal Keratocyte Response to Micro- and Nano-Gratings on Chitosan and PDMS

(2011) Stephanie Koo et al.   Cellular and Molecular Bioengineering

Thermo-responsive poly(N-isopropylacrylamide) grafted onto microtextured poly(dimethylsiloxane) for aligned cell sheet engineering

(2011) Jenny B. Lin et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Transparency in a Fibrin and Fibrin–Agarose Corneal Stroma Substitute Generated by Tissue Engineering

(2011) Juan de la Cruz Cardona et al.   CORNEA

Effect of Microtopographical Cues on Human Keratocyte Orientation and Gene Expression

(2011) Kong Y. Then et al.   CURRENT EYE RESEARCH

Sphere formation from corneal keratocytes and phenotype specific markers

(2011) Sherri-Gae Scott et al.   EXPERIMENTAL EYE RESEARCH

AlphaCor artificial cornea: clinical outcome

(2011) N Jirásková et al.   EYE

Collagen fibril diameter and alignment promote the quiescent keratocyte phenotype

(2011) Lalitha Muthusubramaniam et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Toward the development of an artificial cornea: Improved stability of interpenetrating polymer networks

(2011) Laura Hartmann et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Collagen V is a dominant regulator of collagen fibrillogenesis: dysfunctional regulation of structure and function in a corneal-stroma-specific Col5a1-null mouse model

(2011) M. Sun et al.   JOURNAL OF CELL SCIENCE

Preferential cell response to anisotropic electro-spun fibrous scaffolds under tension-free conditions

(2011) A. English et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Investigating a novel nanostructured fibrin–agarose biomaterial for human cornea tissue engineering: Rheological properties

(2011) Ana-Maria Ionescu et al.   Journal of the Mechanical Behavior of Biomedical Materials

Tissue engineering by self-assembly

(2011) Marissa Peck et al.   Materials Today

Reproducible subcutaneous transplantation of cell sheets into recipient mice

(2011) Haruko Obokata et al.   Nature Protocols

Gene therapy in the Cornea: 2005–present

(2011) Rajiv R. Mohan et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Layer-by-Layer Assembly of Chitosan and Recombinant Biopolymers into Biomimetic Coatings with Multiple Stimuli-Responsive Properties

(2011) Rui R. Costa et al.   Small

Effect of αGal on corneal xenotransplantation in a mouse model

(2011) Hyuk Jin Choi et al.   XENOTRANSPLANTATION

Scaffold-free cell delivery for use in regenerative medicine☆

(2010) Jens M. Kelm et al.   ADVANCED DRUG DELIVERY REVIEWS

Engineering the Extracellular Environment: Strategies for Building 2D and 3D Cellular Structures

(2010) Orane Guillame-Gentil et al.   ADVANCED MATERIALS

Use of magnetically oriented orthogonal collagen scaffolds for hemi-corneal reconstruction and regeneration

(2010) Nicolas Builles et al.   BIOMATERIALS

Helicoidal multi-lamellar features of RGD-functionalized silk biomaterials for corneal tissue engineering

(2010) Eun Seok Gil et al.   BIOMATERIALS

Keratoprostheses in clinical practice - a review

(2010) Ahmed Gomaa et al.   CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Xenotransplantation-The Future of Corneal Transplantation?

(2010) Hidetaka Hara et al.   CORNEA

The molecular basis of corneal transparency

(2010) John R. Hassell et al.   EXPERIMENTAL EYE RESEARCH

Decorin transfection suppresses profibrogenic genes and myofibroblast formation in human corneal fibroblasts

(2010) Rajiv R. Mohan et al.   EXPERIMENTAL EYE RESEARCH

Matrix metalloproteinase 14 overexpression reduces corneal scarring

(2010) S D Galiacy et al.   GENE THERAPY

Role of keratan sulphate (sulphated poly -N-acetyllactosamine repeats) in keratoconic cornea, histochemical, and ultrastructural analysis

(2010) S. Akhtar et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Ocular Biocompatibility of Carbodiimide Cross-Linked Hyaluronic Acid Hydrogels for Cell Sheet Delivery Carriers

(2010) Jui-Yang Lai et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

The effect of keratoconus on the structural, mechanical, and optical properties of the cornea

(2010) Raghu Ambekar et al.   Journal of the Mechanical Behavior of Biomedical Materials

Response of Human Corneal Fibroblasts on Silk Film Surface Patterns

(2010) Eun Seok Gil et al.   MACROMOLECULAR BIOSCIENCE

Enhanced cell accumulation and collagen processing by keratocytes cultured under agarose and in media containing IGF-I, TGF-β or PDGF

(2010) LaTia Etheredge et al.   MATRIX BIOLOGY

Immune Privilege of Corneal Allografts

(2010) Jerry Y. Niederkorn et al.   OCULAR IMMUNOLOGY AND INFLAMMATION

Effect of Substrate Composition and Alignment on Corneal Cell Phenotype

(2010) Donna Phu et al.   TISSUE ENGINEERING PART A

Optimization of chemically defined cell culture media – Replacing fetal bovine serum in mammalian in vitro methods

(2010) J. van der Valk et al.   TOXICOLOGY IN VITRO

Isolation and cultivation of equine corneal keratocytes, fibroblasts and myofibroblasts

(2010) Dylan G. Buss et al.   VETERINARY OPHTHALMOLOGY

Decellularization of bovine corneas for tissue engineering applications

(2009) Sara Ponce Márquez et al.   Acta Biomaterialia

Collagen and glycopolymer based hydrogel for potential corneal application

(2009) Chao Deng et al.   Acta Biomaterialia

In Vitro Sealing of Clear Corneal Cataract Incisions With a Novel Biodendrimer Adhesive

(2009) C. Starck Johnson   ARCHIVES OF OPHTHALMOLOGY

Comparison of Sutures and Dendritic Polymer Adhesives for Corneal Laceration Repair in an In Vivo Chicken Model

(2009) John P. Berdahl   ARCHIVES OF OPHTHALMOLOGY

Fabrication of transferable micropatterned-co-cultured cell sheets with microcontact printing

(2009) Imen Elloumi Hannachi et al.   BIOMATERIALS

Regeneration of functional nerves within full thickness collagen–phosphorylcholine corneal substitute implants in guinea pigs

(2009) Christopher R. McLaughlin et al.   BIOMATERIALS

Reconstruction of a Tissue-Engineered Cornea with Porcine Corneal Acellular Matrix as the Scaffold

(2009) Yao Fu et al.   CELLS TISSUES ORGANS

Corneal Regeneration Following Implantation of a Biomimetic Tissue-Engineered Substitute

(2009) Per Fagerholm et al.   CTS-Clinical and Translational Science

Genetically Engineered Elastin-Like Polymer as a Substratum to Culture Cells from the Ocular Surface

(2009) Hernán Martínez-Osorio et al.   CURRENT EYE RESEARCH

Artificial corneas: a regenerative medicine approach

(2009) M Griffith et al.   EYE

Amniotic membrane in ophthalmology: indications and limitations

(2009) I Rahman et al.   EYE

Transplantation of cultivated oral mucosal epithelial cells for severe corneal burn

(2009) D H-K Ma et al.   EYE

Crowded Cell-like Environment Accelerates the Nucleation Step of Amyloidogenic Protein Misfolding

(2009) Zheng Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Collagen vitrigel membranes for thein vitroreconstruction of separate corneal epithelial, stromal, and endothelial cell layers

(2009) Winnette McIntosh Ambrose et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Synthesis and characterization of a chondroitin sulfate-polyethylene glycol corneal adhesive

(2009) Iossif Strehin et al.   JOURNAL OF CATARACT AND REFRACTIVE SURGERY

Electrical interaction between cardiomyocyte sheets separated by non-cardiomyocyte sheets in heterogeneous tissues

(2009) Yuji Haraguchi et al.   Journal of Tissue Engineering and Regenerative Medicine

Modular tissue engineering: engineering biological tissues from the bottom up

(2009) Jason W. Nichol et al.   Soft Matter

Stem Cell Therapy Restores Transparency to Defective Murine Corneas

(2009) Yiqin Du et al.   STEM CELLS

Effect of Serum and Insulin Modulation on the Organization and Morphology of Matrix Synthesized by Bovine Corneal Stromal Cells

(2009) Ericka M. Bueno et al.   TISSUE ENGINEERING PART A

Recreating the Microenvironment of the Native Cornea for Tissue Engineering Applications

(2009) Lindsay S. Wray et al.   TISSUE ENGINEERING PART A

Formation of Keratocyte Spheroids on Chitosan-Coated Surface Can Maintain Keratocyte Phenotypes

(2009) Yi-Hsin Chen et al.   TISSUE ENGINEERING PART A

Keratocyte behavior in three-dimensional photopolymerizable poly(ethylene glycol) hydrogels

(2008) Nerea Garagorri et al.   Acta Biomaterialia

Guiding Protein Aggregation with Macromolecular Crowding†

(2008) Larissa A. Munishkina et al.   BIOCHEMISTRY

A thermoresponsive, microtextured substrate for cell sheet engineering with defined structural organization

(2008) Brett C. Isenberg et al.   BIOMATERIALS

Recombinant human collagen for tissue engineered corneal substitutes

(2008) Wenguang Liu et al.   BIOMATERIALS

PEG-stabilized carbodiimide crosslinked collagen–chitosan hydrogels for corneal tissue engineering

(2008) Mehrdad Rafat et al.   BIOMATERIALS

Collagen–phosphorylcholine interpenetrating network hydrogels as corneal substitutes

(2008) Wenguang Liu et al.   BIOMATERIALS

Silk film biomaterials for cornea tissue engineering

(2008) Brian D. Lawrence et al.   BIOMATERIALS

Regeneration of Corneal Cells and Nerves in an Implanted Collagen Corneal Substitute

(2008) Christopher R McLaughlin et al.   CORNEA

Glucose-Permeable Interpenetrating Polymer Network Hydrogels for Corneal Implant Applications: A Pilot Study

(2008) David Myung et al.   CURRENT EYE RESEARCH

Human primary corneal fibroblasts synthesize and deposit proteoglycans in long-term 3-D cultures

(2008) R. Ren et al.   DEVELOPMENTAL DYNAMICS

Scaffolding in tissue engineering: general approaches and tissue-specific considerations

(2008) B. P. Chan et al.   EUROPEAN SPINE JOURNAL

Increased stromal extracellular matrix synthesis and assembly by insulin activated bovine keratocytes cultured under agarose

(2008) John R. Hassell et al.   EXPERIMENTAL EYE RESEARCH

The role of oxygen availability in embryonic development and stem cell function

(2008) M. Celeste Simon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Prelude to corneal tissue engineering – Gaining control of collagen organization

(2008) Jeffrey W. Ruberti et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Foreign body reaction to biomaterials

(2008) James M. Anderson et al.   SEMINARS IN IMMUNOLOGY

A thermoreversible hydrogel as a biosynthetic bandage for corneal wound repair

(2007) Chayanin Pratoomsoot et al.   BIOMATERIALS

Carbodiimide cross-linked hyaluronic acid hydrogels as cell sheet delivery vehicles: characterization and interaction with corneal endothelial cells

(2007) Pei-Lin Lu et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION