Article
Cardiac & Cardiovascular Systems
Dimitrios Terentes-Printzios, Vasiliki Gardikioti, Konstantinos Aznaouridis, George Latsios, Maria Drakopoulou, Gerasimos Siasos, Evangelos Oikonomou, Vasiliki Tsigkou, Maria Xanthopoulou, Manolis Vavuranakis, Konstantinos Toutouzas, Dimitrios Tousoulis, Charalambos Vlachopoulos
Summary: The study found that arterial stiffness significantly increases in patients with aortic valve stenosis who undergo TAVI, especially in the long term. Additionally, there are improvements in arterial pressure indices and subendocardial viability ratio after the surgery.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Alberto Alperi, Josep Rodes-Cabau, Matheus Simonato, Didier Tchetche, Gaetan Charbonnier, Henrique B. Ribeiro, Azeem Latib, Matteo Montorfano, Marco Barbanti, Sabine Bleiziffer, Bjorn Redfors, Mohamed Abdel-Wahab, Abdelhakim Allali, Giuseppe Bruschi, Massimo Napodano, Marco Agrifoglio, Anna Sonia Petronio, Cristina Giannini, Albert Chan, Ran Kornowski, Nili Schamroth Pravda, Matti Adam, Alessandro Iadanza, Stephane Noble, Andrew Chatfield, Magdalena Erlebach, Joerg Kempfert, Timm Ubben, Harindra Wijeysundera, Moritz Seiffert, Thomas Pilgrim, Won-Keun Kim, Luca Testa, David Hildick-Smith, Roberto Nerla, Claudia Fiorina, Christina Brinkmann, Lars Conzelmann, Didier Champagnac, Francesco Saia, Henrik Nissen, Hafid Amrane, Brian Whisenant, Jasmin Shamekhi, Lars Sondergaard, John G. Webb, Danny Dvir
Summary: In a large series of ViV-TAVR procedures, the incidence of periprocedural PPI was relatively low and decreased with the use of new-generation THV systems. Older age, larger THV size, and previous right bundle branch block were associated with an increased risk of PPI. Although there were no significant differences in 30-day mortality between the PPI and no-PPI groups, PPI patients exhibited a trend toward higher mortality risk at follow-up.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Jacek Kwiecinski, Evangelos Tzolos, Timothy R. G. Cartlidge, Alexander Fletcher, Mhairi K. Doris, Rong Bing, Jason M. Tarkin, Michael A. Seidman, Gaurav S. Gulsin, Nicholas L. Cruden, Anna K. Barton, Neal G. Uren, Michelle C. Williams, Edwin J. R. van Beek, Jonathon Leipsic, Damini Dey, Raj R. Makkar, Piotr J. Slomka, James H. F. Rudd, David E. Newby, Stephanie L. Sellers, Daniel S. Berman, Marc R. Dweck
Summary: The study aimed to assess the disease activity in native aortic valves and durability of bioprosthetic valves in patients who underwent TAVI, comparing them with those who had bioprosthetic SAVR. The findings suggest that TAVI patients show ongoing disease activity in their native aortic valves, but the durability of bioprosthetic valves in TAVI is similar to that in bioprosthetic SAVR in the midterm.
Article
Mechanics
Jihun Kang, Hyun Jung Koo, Dong Hyun Yang, Hojin Ha
Summary: This study investigates the mechanism of thrombus formation after transcatheter aortic valve implantation (TAVI) and suggests that patients with long native leaflets in their aortic sinus are at a higher risk of thrombosis and may require additional treatment.
Article
Medicine, General & Internal
William D. Toff, David Hildick-Smith, Jan Kovac, Michael J. Mullen, Olaf Wendler, Anita Mansouri, Ines Rombach, Keith R. Abrams, Simon P. Conroy, Marcus D. Flather, Alastair M. Gray, Philip MacCarthy, Mark J. Monaghan, Bernard Prendergast, Simon Ray, Christopher P. Young, David C. Crossman, John G. F. Cleland, Mark A. de Belder, Peter F. Ludman, Stephen Jones, Cameron G. Densem, Steven Tsui, Manoj Kuduvalli, Joseph D. Mills, Adrian P. Banning, Rana Sayeed, Ragheb Hasan, Douglas G. W. Fraser, Uday Trivedi, Simon W. Davies, Alison Duncan, Nick Curzen, Sunil K. Ohri, Christopher J. Malkin, Pankaj Kaul, Douglas F. Muir, W. Andrew Owens, Neal G. Uren, Renzo Pessotto, Simon Kennon, Wael Awad, Saib S. Khogali, Maciej Matuszewski, Richard J. Edwards, Bandigowdanapalya C. Ramesh, Miles Dalby, Shahzad G. Raja, Giovanni Mariscalco, Clinton Lloyd, Ian D. Cox, Simon R. Redwood, Mark G. Gunning, Paul D. Ridley
Summary: This study aimed to determine whether TAVI was noninferior to surgery in patients at moderately increased operative risk. The results showed that among patients aged 70 years or older with severe, symptomatic aortic stenosis and moderately increased operative risk, TAVI was noninferior to surgery with respect to all-cause mortality at 1 year.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2022)
Review
Cardiac & Cardiovascular Systems
Giulia Costa, Marco Angelillis, Anna Sonia Petronio
Summary: Transcatheter aortic valve implantation (TAVI) is an established therapy for severe aortic stenosis, with expanding indications towards younger patients. However, the presence of bicuspid aortic valve (BAV) poses challenges due to its anatomical features and lack of consensus on optimal sizing strategy. This paper aims to review the unique aspects of BAV and discuss the currently available sizing methods, emphasizing the role of pre-procedural imaging and aspects to consider for optimal procedural planning.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Medicine, General & Internal
Lola Gutierrez, Mauro Boiago, Chiara De Biase, Omar Oliva, Pietro Laforgia, Souheib Feliachi, Alessandro Beneduce, Nicolas Dumonteil, Didier Tchetche
Summary: Bicuspid aortic valve disease is the most common congenital heart disease, associated with unique morphological features and lack of consensus in sizing measurement. Multi-slice computed tomography plays a crucial role in TAVI procedure planning, and advancements in devices and procedure planning have improved clinical outcomes.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Peripheral Vascular Disease
Ning Song, Audrey I. Adji, Sara L. Hungerford, Mayooran J. Namasivayam, Christopher S. Hayward, Andrew Jabbour, David W. M. Muller
Summary: This study found that arterial stiffening has a significant impact on pulsatile left ventricular afterload in patients with aortic stenosis, beyond the effect of systemic hypertension. Circulatory afterload pulsatile efficiency (CAPE) was used as an indicator of vascular function, measuring the ratio of steady state energy consumption (SEC) to pulsatile energy consumption (PEC) required to maintain systemic circulation. After transcatheter aortic valve replacement (TAVR), eight out of 20 patients showed a reduction in PEC, which was strongly correlated with the number of days post TAVR. Patients assessed within 100 days of TAVR had an increase in PEC compared to baseline. Overall, no significant differences were found in various parameters of arterial function between baseline and post TAVR. Improved flow profiles after TAVR likely contribute to vascular remodeling and improvement of pulsatile afterload, as reflected by the proposed index of CAPE.
HYPERTENSION RESEARCH
(2023)
Review
Medicine, General & Internal
Ana Paula Tagliari, Rodrigo Petersen Saadi, Eduardo Keller Saadi
Summary: TAVI is a well-established procedure for treating aortic stenosis, but using it for high-risk patients with pure native aortic regurgitation is considered an off-label intervention, especially when the aortic annulus dimensions are beyond the recommended range.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Medicine, General & Internal
Simona Sperlongano, Francesca Renon, Maurizio Cappelli Bigazzi, Rossella Sperlongano, Giovanni Cimmino, Antonello D'Andrea, Paolo Golino
Summary: Cardiac rehabilitation (CR) after transcatheter aortic valve implantation (TAVI) can improve exercise tolerance and quality of life in patients, and potentially reduce mortality during follow-up. While major guidelines currently do not recommend CR after TAVI, emerging scientific evidence supports the benefits of such programs.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Taishi Okuno, Caglayan Demirel, Daijiro Tomii, Gabor Erdoes, Dik Heg, Jonas Lanz, Fabien Praz, Rainer Zbinden, David Reineke, Lorenz Raber, Stefan Stortecky, Stephan Windecker, Thomas Pilgrim
Summary: This study aimed to evaluate the risk of noncardiac surgery after TAVI. The results suggest that noncardiac surgery can be performed early after successful TAVI, and device performance may impact the risk of adverse outcomes after surgery.
Review
Medicine, General & Internal
Louhai Alwan, Benedikt Bernhard, Nicolas Brugger, Stefano F. de Marchi, Fabien Praz, Stephan Windecker, Thomas Pilgrim, Christoph Grani
Summary: Transcatheter aortic valve implantation (TAVI) has become the standard of care for elderly high-risk patients with symptomatic severe aortic stenosis. However, diagnosing bioprosthetic valve dysfunction after TAVI is challenging and there are limited evidence-based criteria to guide therapy. This review focuses on the role of imaging modalities in monitoring the integrity of transcatheter heart valves.
Article
Multidisciplinary Sciences
Anne Caroline Wolpers, Thomas Welchowski, Alexander Sedaghat, Maximilian W. M. Wintergerst, Baravan Al-Kassou, Robert P. Finger, Jan Henrik Terheyden
Summary: Cerebral embolization is a known complication of transcatheter aortic valve implantation (TAVI), but the effect of the procedure on ocular perfusion is unclear. This study found that TAVI resulted in reduced choroidal perfusion, areas of retinal ischemia, and embolization in a considerable proportion of patients. These complications should be monitored and included in consent procedures for TAVI.
SCIENTIFIC REPORTS
(2023)
Review
Medicine, General & Internal
Pier Pasquale Leone, Andrea Scotti, Edwin C. Ho, Manaf Assafin, James Doolittle, Mei Chau, Leandro Slipczuk, Matthew Levitus, Damiano Regazzoli, Antonio Mangieri, Azeem Latib
Summary: Transcatheter aortic valve implantation (TAVI) has emerged as a safe and effective alternative to surgical aortic valve replacement for severe aortic stenosis. This review focuses on commercially available TAVI devices and provides a guide for selecting the appropriate prosthesis based on patient-related factors.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Gabriele Pesarini, Gabriele Venturi, Domenico Tavella, Leonardo Gottin, Mattia Lunardi, Elena Mirandola, Francesco Onorati, Giuseppe Faggian, Flavio Ribichini
Summary: This research describes the performance of transcatheter aortic valve implantations (TAVIs) in a high-volume center with a real-world population, highlighting the significant impact of operator experience on clinical outcomes, especially in high-risk patients.
JOURNAL OF CLINICAL MEDICINE
(2021)
