Review
Oncology
Monica Ribeiro, Mohamed Amine Benadjaoud, Laura Moisy, Julian Jacob, Loic Feuvret, Alexander Balcerac, Marie-Odile Bernier, Dimitri Psimaras, Khe Hoang-Xuan, Georges Noel, Nathalie Jouniaux-Delbez, Damien Ricard
Summary: High-grade glioma patients are at high risk of developing depression and anxiety symptoms at different stages of the disease. Early palliative care and personalized psychosocial interventions are essential for improving patients' quality of life.
Article
Medicine, General & Internal
Meaghann S. Weaver, Shana S. Jacobs, Janice S. Withycombe, Jichuan Wang, Katie A. Greenzang, Justin N. Baker, Pamela S. Hinds
Summary: The results of this cohort study suggest that there is alignment between proxy caregiver reports and children's self-reports of symptoms. Proxy reports can serve as a guide to care when the child is unable to self-report.
Review
Endocrinology & Metabolism
Jiaojiao Yuan, Shuo Qi, Xufan Zhang, Hezheng Lai, Xinyi Li, Xiaoheng Chen, Zhe Li, Simiao Yao, Zhiguo Ding
Summary: This study aimed to investigate the local symptoms of Hashimoto's thyroiditis (HT) and their prevalence. The common local symptoms in HT patients include neck pain, voice changes, throat discomfort, shortness of breath, dysphagia, and goiter-related symptoms. These symptoms should be identified in the clinic and included in the early diagnosis and management of HT.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Medicine, General & Internal
Yue Hu, Fang Deng, Lupeng Zhang, Keyue Hu, Shiqi Liu, Suye Zhong, Jun Yang, Xiaomin Zeng, Xiaoning Peng
Summary: Depression is a common complication in patients with gliomas, and it can severely affect their psychological well-being and quality of life. Risk factors for depression in these patients include female sex, unmarried status, low education level, high tumor grade, and a history of mental illness. Antidepressant use can improve the prognosis of patients with gliomas.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Chemistry, Medicinal
Reyhaneh Gudarzi, Fatemeh Shabani, Sakineh Mohammad-Alizadeh-Charandabi, Elham Naghshineh, Elnaz Shaseb, Mojgan Mirghafourvand
Summary: This study aimed to determine the effect of curcumin on painful symptoms and quality of life in women with endometriosis. The results showed that curcumin did not have a significant impact on pain symptoms or quality of life. Future clinical trials are needed to further investigate the role of curcumin in endometriosis.
PHYTOTHERAPY RESEARCH
(2023)
Article
Clinical Neurology
Parisa Hajihashemi, Fahimeh Haghighatdoost, Noushin Mohammadifard, Maryam Maghroun, Firouzeh Sajjadi, Farid Najafi, Hossein Farshidi, Masoud Lotfizadeh, Kamal Solati, Tooba Kazemi, Simin Karimi, Hamidreza Roohafza, Mohammadreza Sabri, Cesar de Oliveira, Erika Aparecida Silveira, Nizal Sarrafzadegan
Summary: This study investigated the potential relationship between Macronutrients' quality and mental health and quality of life among Iranian adults. The results showed that higher protein quality index (PQI) was associated with lower risk of depressive symptoms and low-quality life. However, carbohydrate quality index (CQI) and fat quality index (FQI) were not related to depressive and anxiety symptoms.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Psychology, Multidisciplinary
Sophie Nothel, Annika Nuebold, Sjir Uitdewilligen, Jan Schepers, Ute Hulsheger
Summary: This study developed and validated a new leadership instrument, the Adaptive Leadership Behavior Scale (ALBS), to assess adaptive leadership behavior. Through multiple field studies, it was found that ALBS is a concise and valid tool that can contribute to our understanding of the antecedents, mechanisms, and consequences of leadership in dynamic environments.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Oncology
Linda Koehler, Lauren Elyse Penz, Florence John, Ashley Stenzel, Patricia Jewett, Deanna Teoh, Anne Blaes, Colleen Rivard, Rachel Vogel
Summary: The aim of this study was to compare the differences in function, quality of life, body image, and distress levels between gynecologic cancer survivors with and without lymphedema symptoms, and determine the number of individuals who received rehabilitation treatment following treatment for gynecological malignancy. The findings showed that participants in the symptomatic group had lower quality of life, lower function scores, and greater cancer-related distress, with higher rates of clinically significant levels of distress. These results remained largely consistent in multivariable models.
GYNECOLOGIC ONCOLOGY
(2023)
Article
Multidisciplinary Sciences
Ana D. Jotic, Ana M. Opankovic, Zorana Z. Radin, Ljiljana Cvorovic, Katarina R. Savic Vujovic, Sanja B. Krejovic-Trivic, Bojana M. Bukurov, Biljana R. Milicic, Jasmina D. Stojanovic
Summary: The study found that in patients with chronic otitis media, 70.57% had some level of anxiety, 49.37% had some level of stress, and 13.29% had symptoms of depression. The severity of otitis media symptoms was significantly associated with patients' depression, anxiety, and stress levels.
Article
Psychiatry
Eric Josiah Tan, Wei Lin Toh, Susan Lee Rossell
Summary: This study examined the relationship between state and trait symptoms of schizophrenia and quality of life. The findings showed that negative state symptoms were related to objective quality of life in patients, while negative trait symptoms were associated with both objective and subjective quality of life in patients and healthy controls.
PSYCHIATRY RESEARCH
(2022)
Article
Neurosciences
Tatiana Usnich, Bjoern Hauptmann, Henrike Hanssen, Jannik Prasuhn, Alexander Balck, Max Borsche, Vera Tadic, Annika Klee, Greta Noblejas-Sanchez, Eva-Juliane Vollstedt, Christine Klein, Norbert Brueggemann, Meike Kasten, EPIPARK Study Grp
Summary: Depressive symptoms in Parkinson's disease (PD) are multifactorial, including both dopaminergic deficit and chronic illness-related reactions. The prevalence and severity of depressive symptoms are similar between PD patients and disease controls (DC), though PD patients use antidepressants, especially Mirtazapine, more frequently. However, a significant proportion of patients in both groups with clinically significant depressive symptoms were not receiving medication. The diagnosis and treatment of depressive symptoms in both PD and DC should be improved.
NPJ PARKINSONS DISEASE
(2023)
Article
Psychology, Clinical
Cheng-Chung Cho
Summary: The purpose of this study was to investigate the impact of work stress on job burnout and quality of life, and the moderating effect of group factors (transformational leadership and group member interactions) on this relationship. The study focused on front-line border police and used a cross-level perspective to examine the effects of work stress on work efficiency and health indicators.
PSYCHOLOGY RESEARCH AND BEHAVIOR MANAGEMENT
(2023)
Article
Clinical Neurology
Meredith A. Bock, Ethan G. Brown, Li Zhang, Caroline Tanner
Summary: This study found significant correlations between depression, motor symptoms, medical comorbidities, and HRQOL in a large online cohort of Parkinson's disease patients. Neuropsychiatric symptoms and falls had the most negative impact on HRQOL. Motor symptoms may have differential effects on HRQOL in different demographic and clinical subpopulations.
Article
Radiology, Nuclear Medicine & Medical Imaging
Xiangliang Wang, Di Chen, Jianjian Qiu, Shihong Li, Xiangpeng Zheng
Summary: The combination therapy of BEV and TMZ could improve cognitive function and quality of life in patients with recurrent high-grade gliomas compared to TMZ alone. The Edema Regression Index may serve as a surrogate imaging biomarker to predict cognitive benefits in patients receiving combination therapy. Further prospective clinical studies are needed to validate these findings.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2021)
Article
Clinical Neurology
Laura L. Laslett, Cynthia Honan, Jason A. Turner, Baye Dagnew, Julie A. Campbell, Tiffany K. Gill, Sarah Appleton, Leigh Blizzard, Bruce Taylor, Ingrid van der Mei
Summary: Poor sleep quality is common in people with multiple sclerosis (MS), and strongly associated with worse health-related quality of life. This association is independent of other MS symptoms and does not cluster with other common MS symptoms.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2022)
Article
Oncology
Mallika P. Patel, Sarah Woodring, Dina M. Randazzo, Henry S. Friedman, Annick Desjardins, Patrick Healy, James E. Herndon, Frances McSherry, Eric S. Lipp, Elizabeth Miller, Katherine B. Peters, Mary Lou Affronti
SUPPORTIVE CARE IN CANCER
(2020)
Article
Integrative & Complementary Medicine
Dina M. Randazzo, Frances McSherry, James E. Herndon, Mary L. Affronti, Eric S. Lipp, Charlene Flahiff, Elizabeth Miller, Sarah Woodring, Susan Boulton, Annick Desjardins, David M. Ashley, Henry S. Friedman, Katherine B. Peters
COMPLEMENTARY THERAPIES IN CLINICAL PRACTICE
(2019)
Article
Clinical Neurology
Christian Thomas, Annika Wefers, Susanne Bens, Karolina Nemes, Abbas Agaimy, Florian Oyen, Silke Vogelgesang, Fausto J. Rodriguez, Francesca M. Brett, Roger McLendon, Istvan Bodi, Fanny Burel-Vandenbos, Kathy Keyvani, Stefan Tippelt, Frantz R. Poulsen, Eric S. Lipp, Caterina Giannini, Guido Reifenberger, Klaus Kuchelmeister, Torsten Pietsch, Uwe Kordes, Reiner Siebert, Michael C. Fruehwald, Pascal D. Johann, Martin Sill, Marcel Kool, Andreas von Deimling, Werner Paulus, Martin Hasselblatt
ACTA NEUROPATHOLOGICA
(2020)
Article
Oncology
Mallika P. Patel, John P. Kirkpatrick, Margaret O. Johnson, Patrick Healy, James E. Herndon, Eric S. Lipp, Elizabeth S. Miller, Annick Desjardins, Dina Randazzo, Henry S. Friedman, David M. Ashley, Katherine B. Peters
JOURNAL OF NEURO-ONCOLOGY
(2020)
Article
Oncology
Alex Broom, Katherine Kenny, Alexander Page, Nicole Cort, Eric S. Lipp, Aaron C. Tan, David M. Ashley, Kyle M. Walsh, Mustafa Khasraw
CLINICAL CANCER RESEARCH
(2020)
Article
Multidisciplinary Sciences
Matthias Gromeier, Michael C. Brown, Gao Zhang, Xiang Lin, Yeqing Chen, Zhi Wei, Nike Beaubier, Hai Yan, Yiping He, Annick Desjardins, James E. Herndon, Frederick S. Varn, Roel G. Verhaak, Junfei Zhao, Dani P. Bolognesi, Allan H. Friedman, Henry S. Friedman, Frances McSherry, Andrea M. Muscat, Eric S. Lipp, Smita K. Nair, Mustafa Khasraw, Katherine B. Peters, Dina Randazzo, John H. Sampson, Roger E. McLendon, Darell D. Bigner, David M. Ashley
Summary: The study found that low tumor mutation burden is associated with longer survival after immunotherapy in recurrent glioblastoma patients, and this relationship is related to inflammatory gene signatures, which evolves upon recurrence.
NATURE COMMUNICATIONS
(2021)
Article
Oncology
Jessica W. Lee, John P. Kirkpatrick, Frances McSherry, James E. Herndon, Eric S. Lipp, Annick Desjardins, Dina M. Randazzo, Henry S. Friedman, David M. Ashley, Katherine B. Peters, Margaret O. Johnson
Summary: In this study of older patients with GBM, age and KPS were associated with the choice between short-course and standard RT. Both regimens showed similar overall survival, but some patients experienced worsening symptoms and discontinued treatment during RT. Further research into predictors of RT completion and survival could help improve adjuvant therapy and supportive care for older patients.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Katherine B. Peters, Mary L. Affronti, Sarah Woodring, Eric Lipp, Patrick Healy, James E. Herndon, Elizabeth S. Miller, Maria W. Freeman, Dina M. Randazzo, Annick Desjardins, Henry S. Friedman
Summary: A placebo-controlled, double-blind study showed that low-dose naltrexone (LDN) did not have a significant impact on quality of life and fatigue in patients with high-grade glioma (HGG) during concurrent chemotherapy and radiation therapy.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Clinical Neurology
Mallika P. Patel, Eric S. Lipp, Elizabeth S. Miller, Patrick N. Healy, James E. Herndon, Katherine B. Peters
Summary: The study found that most clinical members in the surveyed neuro-oncology community do not have the support or expertise of dedicated neuro-oncology pharmacists, despite the demanding nature of their outpatient practices.
NEURO-ONCOLOGY PRACTICE
(2022)
Article
Clinical Neurology
Alexander Yuile, Mustafa Khasraw, Justin T. Low, Kyle M. Walsh, Eric Lipp, Joanne Sy, Laveniya Satgunaseelan, Marina Ann Kastelan, Madhawa De Silva, Adrian Lee, Helen Wheeler
Summary: This study investigates the current patterns of clinical practice for histone mutant gliomas (HMG) in Australia and the United States (US). The results show variations in testing methods and treatment approaches for HMG patients, and the knowledge of H3 mutations impacts the management of these gliomas, particularly during recurrence.
NEURO-ONCOLOGY PRACTICE
(2022)
Article
Hematology
Kirsten Bell Burdett, Dusten Unruh, Michael Drumm, Alicia Steffens, Jonathan Lamano, Jonathan Judkins, Margaret Schwartz, Rodrigo Javier, Christina Amidei, Eric S. Lipp, Katherine B. Peters, Albert Lai, Blaine S. C. Eldred, Amy B. Heimberger, Kathleen McCortney, Denise M. Scholtens, Craig Horbinski
Summary: The study developed a VTE prediction tool to improve care for adult-type diffuse glioma patients, incorporating clinical, blood-based, histologic, and molecular markers. Analysis of data from 258 newly diagnosed patients revealed that tumor expression of TF and PDPN correlated with VTE, and circulating TF and D-dimers correlated with VTE risk. Several factors, including past VTE history, hypertension, asthma, white blood cell count, WHO tumor grade, patient age, and body mass index, predicted increased VTE risk in newly diagnosed glioma patients. Conversely, IDH mutation, hypothyroidism, and MGMT promoter methylation predicted reduced VTE risk.
Article
Oncology
Emily Hanzlik, Bridget Archambault, Mays El-Dairi, Kristin Schroeder, Mallika P. Patel, Eric S. Lipp, Katherine B. Peters, David M. Ashley, Daniel Landi
Summary: A retrospective chart review showed that trametinib is effective and well-tolerated in patients with progressive low-grade glioma. The best radiographic response was seen after a longer duration of therapy, and patients with optic pathway lesions showed stable to improved vision while on treatment.
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
(2023)
Article
Clinical Neurology
Dina M. Randazzo, Frances McSherry, James E. Herndon, Mary L. Affronti, Eric S. Lipp, Elizabeth S. Miller, Sarah Woodring, Patrick Healy, Jennifer Jackman, Brian Crouch, Annick Desjardins, David M. Ashley, Henry S. Friedman, Katherine B. Peters
Summary: This study aimed to investigate the association between spiritual well-being (SWB) and health-related quality of life (HRQoL) in primary brain tumor patients. The results showed that higher SWB was associated with better HRQoL, emphasizing the importance of spiritual aspects in strategies to improve HRQoL in primary brain tumor patients.
NEURO-ONCOLOGY PRACTICE
(2021)
Letter
Oncology
Erica Shen, Margaret O. Johnson, Jessica W. Lee, Eric S. Lipp, Dina M. Randazzo, Annick Desjardins, Roger E. McLendon, Henry S. Friedman, David M. Ashley, John P. Kirkpatrick, Katherine B. Peters, Kyle M. Walsh
NEURO-ONCOLOGY ADVANCES
(2019)
Article
Public, Environmental & Occupational Health
Annick Desjardins, James E. Herndon, Frances McSherry, Arliene Ravelo, Eric S. Lipp, Patrick Healy, Katherine B. Peters, John H. Sampson, Dina Randazzo, Nicolas Sommer, Allan H. Friedman, Henry S. Friedman
HEALTH SCIENCE REPORTS
(2019)
