Coxsackievirus A10 atomic structure facilitating the discovery of a broad-spectrum inhibitor against human enteroviruses

A virus-like particle vaccine protects mice against coxsackievirus A10 lethal infection

(2018) Yu Zhou et al.   ANTIVIRAL RESEARCH

KREMEN1 Is a Host Entry Receptor for a Major Group of Enteroviruses

(2018) Jacqueline Staring et al.   Cell Host & Microbe

Severe hand, foot and mouth disease associated with Coxsackievirus A10 infections in Xiamen, China in 2015

(2017) Mengyuan Chen et al.   JOURNAL OF CLINICAL VIROLOGY

A 3.0-Angstrom Resolution Cryo-Electron Microscopy Structure and Antigenic Sites of Coxsackievirus A6-Like Particles

(2017) Jinhuan Chen et al.   JOURNAL OF VIROLOGY

Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody

(2017) Longfa Xu et al.   Nature Communications

Immunological and biochemical characterizations of coxsackievirus A6 and A10 viral particles

(2016) Chia-Chyi Liu et al.   ANTIVIRAL RESEARCH

Coxsackievirus A16-like particles produced in Pichia pastoris elicit high-titer neutralizing antibodies and confer protection against lethal viral challenge in mice

(2016) Chao Zhang et al.   ANTIVIRAL RESEARCH

An algorithm for estimation and correction of anisotropic magnification distortion of cryo-EM images without need of pre-calibration

(2016) Guimei Yu et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structure of the Dual-Mode Wnt Regulator Kremen1 and Insight into Ternary Complex Formation with LRP6 and Dickkopf

(2016) Matthias Zebisch et al.   STRUCTURE

Inactivated coxsackievirus A10 experimental vaccines protect mice against lethal viral challenge

(2016) Chaoyun Shen et al.   VACCINE

Structural Basis for Recognition of Human Enterovirus 71 by a Bivalent Broadly Neutralizing Monoclonal Antibody

(2016) Xiaohua Ye et al.   PLoS Pathogens

Discovery of Itraconazole with Broad-SpectrumIn VitroAntienterovirus Activity That Targets Nonstructural Protein 3A

(2015) Qianqian Gao et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Structures of Coxsackievirus A16 Capsids with Native Antigenicity: Implications for Particle Expansion, Receptor Binding, and Immunogenicity

(2015) Jingshan Ren et al.   JOURNAL OF VIROLOGY

Single Neutralizing Monoclonal Antibodies Targeting the VP1 GH Loop of Enterovirus 71 Inhibit both Virus Attachment and Internalization during Viral Entry

(2015) Zhiqiang Ku et al.   JOURNAL OF VIROLOGY

Structure and inhibition of EV-D68, a virus that causes respiratory illness in children

(2015) Y. Liu et al.   SCIENCE

High-yield production of recombinant virus-like particles of enterovirus 71 in Pichia pastoris and their protective efficacy against oral viral challenge in mice

(2015) Chao Zhang et al.   VACCINE

A new EV71 VP3 epitope in norovirus P particle vector displays neutralizing activity and protection in vivo in mice

(2015) Liping Jiang et al.   VACCINE

The Capsid Binder Vapendavir and the Novel Protease Inhibitor SG85 Inhibit Enterovirus 71 Replication

(2014) Aloys Tijsma et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A virus-like particle based bivalent vaccine confers dual protection against enterovirus 71 and coxsackievirus A16 infections in mice

(2014) Zhiqiang Ku et al.   VACCINE

A Novel Universal Neutralizing Monoclonal Antibody against Enterovirus 71 That Targets the Highly Conserved “Knob” Region of VP3 Protein

(2014) Tanja K. Kiener et al.   PLoS Neglected Tropical Diseases

Molecular mechanism of SCARB2-mediated attachment and uncoating of EV71

(2014) Minghao Dang et al.   Protein & Cell

Emergence, Circulation, and Spatiotemporal Phylogenetic Analysis of Coxsackievirus A6- and Coxsackievirus A10-Associated Hand, Foot, and Mouth Disease Infections from 2008 to 2012 in Shenzhen, China

(2013) Ya-Qing He et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Chimeric Virus-Like Particle Vaccines Displaying Conserved Enterovirus 71 Epitopes Elicit Protective Neutralizing Antibodies in Mice through Divergent Mechanisms

(2013) X. Ye et al.   JOURNAL OF VIROLOGY

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

(2013) Xueming Li et al.   NATURE METHODS

Structure of human enterovirus 71 in complex with a capsid-binding inhibitor

(2013) P. Plevka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of conserved neutralizing linear epitopes within the VP1 protein of coxsackievirus A16

(2013) Jinping Shi et al.   VACCINE

Outbreak of hand, foot and mouth disease/herpangina associated with coxsackievirus A6 and A10 infections in 2010, France: a large citywide, prospective observational study

(2012) A. Mirand et al.   CLINICAL MICROBIOLOGY AND INFECTION

Picornavirus and enterovirus diversity with associated human diseases

(2012) Caroline Tapparel et al.   INFECTION GENETICS AND EVOLUTION

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Characterization of enterovirus 71 capsids using subunit protein-specific polyclonal antibodies

(2012) Qingwei Liu et al.   JOURNAL OF VIROLOGICAL METHODS

Human SCARB2-Dependent Infection by Coxsackievirus A7, A14, and A16 and Enterovirus 71

(2012) S. Yamayoshi et al.   JOURNAL OF VIROLOGY

A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71

(2012) Xiangxi Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Circulation of Coxsackievirus A10 and A6 in Hand-Foot-Mouth Disease in China, 2009–2011

(2012) Qing-Bin Lu et al.   PLoS One

Crystal Structure of Human Enterovirus 71

(2012) P. Plevka et al.   SCIENCE

Combating enterovirus replication: State-of-the-art on antiviral research

(2011) Hendrik Jan Thibaut et al.   BIOCHEMICAL PHARMACOLOGY

Detection of coxsackievirus A10 in multiple tissues of a fatal infant sepsis case

(2011) Meghan E. Fuschino et al.   JOURNAL OF CLINICAL VIROLOGY

Detection, characterization and quantitation of Coxsackievirus A16 using polyclonal antibodies against recombinant capsid subunit proteins

(2011) Qingwei Liu et al.   JOURNAL OF VIROLOGICAL METHODS

Identification and characterization of a cross-neutralization epitope of Enterovirus 71

(2011) Chia-Chyi Liu et al.   VACCINE

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Scavenger receptor B2 is a cellular receptor for enterovirus 71

(2009) Seiya Yamayoshi et al.   NATURE MEDICINE

Development of antiviral agents for enteroviruses

(2008) T.-C. Chen et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY