Assessment of the Immunosuppressive Potential of INF-γ Licensed Adipose Mesenchymal Stem Cells, Their Secretome and Extracellular Vesicles

Insights into inflammatory priming of mesenchymal stromal cells: functional biological impacts

(2018) Mehdi Najar et al.   INFLAMMATION RESEARCH

Mesenchymal stem cells-derived exosomes are more immunosuppressive than microparticles in inflammatory arthritis

(2018) Stella Cosenza et al.   Theranostics

Interferon-γ mediates the immunosuppression of bone marrow mesenchymal stem cells on T-lymphocytes in vitro

(2017) Chen Liang et al.   Hematology

IFN-γ orchestrates mesenchymal stem cell plasticity through the signal transducer and activator of transcription 1 and 3 and mammalian target of rapamycin pathways

(2017) Tiziana Vigo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Induction of Regulatory T Cells and Its Regulation with Insulin-like Growth Factor/Insulin-like Growth Factor Binding Protein-4 by Human Mesenchymal Stem Cells

(2017) Ippei Miyagawa et al.   JOURNAL OF IMMUNOLOGY

Morphological features of IFN-γ–stimulated mesenchymal stromal cells predict overall immunosuppressive capacity

(2017) Matthew W. Klinker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Concise Review: MSC-Derived Exosomes for Cell-Free Therapy

(2017) Donald G. Phinney et al.   STEM CELLS

Molecular Mechanisms of Immunomodulation Properties of Mesenchymal Stromal Cells: A New Insight into the Role of ICAM-1

(2017) Yury Rubtsov et al.   Stem Cells International

Non-coding RNAs in Mesenchymal Stem Cell-Derived Extracellular Vesicles: Deciphering Regulatory Roles in Stem Cell Potency, Inflammatory Resolve, and Tissue Regeneration

(2017) Farah Fatima et al.   Frontiers in Genetics

Mesenchymal Stromal Cells and Toll-Like Receptor Priming: A Critical Review

(2017) Mehdi Najar et al.   Immune Network

Heterogeneity in Studies of Mesenchymal Stromal Cells to Treat or Prevent Graft-versus-Host Disease: A Scoping Review of the Evidence

(2016) Mina Rizk et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Human mesenchymal stromal cells modulate T-cell immune response via transcriptomic regulation

(2016) Shalini Vellasamy et al.   CYTOTHERAPY

DSP30 enhances the immunosuppressive properties of mesenchymal stromal cells and protects their suppressive potential from lipopolysaccharide effects: A potential role of adenosine

(2016) Bruno Sangiorgi et al.   CYTOTHERAPY

The current landscape of the mesenchymal stromal cell secretome: A new paradigm for cell-free regeneration

(2016) Vijay Bhaskar Reddy Konala et al.   CYTOTHERAPY

The Role of Extracellular Vesicle and Tunneling Nanotube-Mediated Intercellular Cross-Talk Between Mesenchymal Stem Cells and Human Peripheral T Cells

(2016) Zsolt Matula et al.   STEM CELLS AND DEVELOPMENT

The Potential of Mesenchymal Stromal Cells as Treatment for Severe Steroid-Refractory Acute Graft-Versus-Host Disease

(2016) J. Marius Munneke et al.   TRANSPLANTATION

Mesenchymal stem cells and immunomodulation: current status and future prospects

(2016) F Gao et al.   Cell Death & Disease

LL-37 boosts immunosuppressive function of placenta-derived mesenchymal stromal cells

(2016) Martha Oliveira-Bravo et al.   Stem Cell Research & Therapy

Modulation of Immunoregulatory Properties of Mesenchymal Stromal Cells by Toll-Like Receptors: Potential Applications on GVHD

(2016) Bruno Sangiorgi et al.   Stem Cells International

Homing and migration of mesenchymal stromal cells: How to improve the efficacy of cell therapy?

(2016) Ann De Becker et al.   World Journal of Stem Cells

IL-10 Potentiates Differentiation of Human Induced Regulatory T Cells via STAT3 and Foxo1

(2015) Peter Hsu et al.   JOURNAL OF IMMUNOLOGY

TNF biology, pathogenic mechanisms and emerging therapeutic strategies

(2015) George D. Kalliolias et al.   Nature Reviews Rheumatology

IDO-Independent Suppression of T Cell Effector Function by IFN- -Licensed Human Mesenchymal Stromal Cells

(2014) R. Chinnadurai et al.   JOURNAL OF IMMUNOLOGY

Mechanisms of T-Cell Immunosuppression by Mesenchymal Stromal Cells: What Do We Know So Far?

(2014) Rodrigo Haddad et al.   Biomed Research International

Immunomodulatory Potential of Human Adipose Mesenchymal Stem Cells Derived Exosomes on in vitro Stimulated T Cells

(2014) Rebeca Blazquez et al.   Frontiers in Immunology

Expression and role of Toll-like receptors on human umbilical cord mesenchymal stromal cells

(2013) Dandan Chen et al.   CYTOTHERAPY

Mesenchymal stem or stromal cells: a review of clinical applications and manufacturing practices

(2013) Ratti Ram Sharma et al.   TRANSFUSION

Circulating mesenchymal stem cells and their clinical implications

(2013) Liangliang Xu et al.   Journal of Orthopaedic Translation

Proteomic Validation of Multifunctional Molecules in Mesenchymal Stem Cells Derived from Human Bone Marrow, Umbilical Cord Blood and Peripheral Blood

(2012) Jumi Kim et al.   PLoS One

Mesenchymal stem cells promote the sustained expression of CD69 on activated T lymphocytes: roles of canonical and non-canonical NF-κB signalling

(2011) Felipe Saldanha-Araujo et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Interferon-γ Regulates the Proliferation and Differentiation of Mesenchymal Stem Cells via Activation of Indoleamine 2,3 Dioxygenase (IDO)

(2011) Juliana Croitoru-Lamoury et al.   PLoS One

Mesenchymal stromal cells up-regulate CD39 and increase adenosine production to suppress activated T-lymphocytes

(2011) Felipe Saldanha-Araujo et al.   Stem Cell Research

Human Mesenchymal Stem Cells from Adipose Tissue and Amnion Influence T-Cells Depending on Stimulation Method and Presence of Other Immune Cells

(2011) Barbara Kronsteiner et al.   STEM CELLS AND DEVELOPMENT

Mesenchymal Stromal Cell Migration: Possibilities to Improve Cellular Therapy

(2011) Marijke W. Maijenburg et al.   STEM CELLS AND DEVELOPMENT

Human multipotent mesenchymal stromal cells use galectin-1 to inhibit immune effector cells

(2010) F. Gieseke et al.   BLOOD

Interferon-γ and Tumor Necrosis Factor-α Differentially Affect Cytokine Expression and Migration Properties of Mesenchymal Stem Cells

(2010) Hatim Hemeda et al.   STEM CELLS AND DEVELOPMENT

Cell contact, prostaglandin E2and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4+CD25Highforkhead box P3+regulatory T cells

(2009) K. English et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Cell contact interaction between adipose-derived stromal cells and allo-activated T lymphocytes

(2009) Monique E. Quaedackers et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Toll-Like Receptor Engagement Enhances the Immunosuppressive Properties of Human Bone Marrow-Derived Mesenchymal Stem Cells by Inducing Indoleamine-2,3-dioxygenase-1 via Interferon-β and Protein Kinase R

(2009) Christiane A. Opitz et al.   STEM CELLS

IFN-γ activation of mesenchymal stem cells for treatment and prevention of graft versus host disease

(2008) David Polchert et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Toll-like Receptor–Mediated Signaling in Human Adipose-Derived Stem Cells: Implications for Immunogenicity and Immunosuppressive Potential

(2008) Eleuterio Lombardo et al.   TISSUE ENGINEERING PART A

Toll-Like Receptors on Human Mesenchymal Stem Cells Drive Their Migration and Immunomodulating Responses

(2007) Suzanne L. Tomchuck et al.   STEM CELLS

Human Leukocyte Antigen-G5 Secretion by Human Mesenchymal Stem Cells Is Required to Suppress T Lymphocyte and Natural Killer Function and to Induce CD4+CD25highFOXP3+Regulatory T Cells

(2007) Zohair Selmani et al.   STEM CELLS