Prognostic Gene Discovery in Glioblastoma Patients using Deep Learning

A graph-embedded deep feedforward network for disease outcome classification and feature selection using gene expression data

(2018) Yunchuan Kong et al.   BIOINFORMATICS

Secretogranin III as a disease-associated ligand for antiangiogenic therapy of diabetic retinopathy

(2017) Michelle E. LeBlanc et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Using Elastic Net Penalized Cox Proportional Hazards Regression to Identify Predictors of Imminent Smoking Lapse

(2017) Robert Suchting et al.   NICOTINE & TOBACCO RESEARCH

Predicting clinical outcomes from large scale cancer genomic profiles with deep survival models

(2017) Safoora Yousefi et al.   Scientific Reports

NNMT Silencing Activates Tumor Suppressor PP2A, Inactivates Oncogenic STKs, and Inhibits Tumor Forming Ability

(2016) Kamalakannan Palanichamy et al.   CLINICAL CANCER RESEARCH

High CHI3L1 expression is associated with glioma patient survival

(2016) Giedrius Steponaitis et al.   Diagnostic Pathology

Periostin (POSTN) Regulates Tumor Resistance to Antiangiogenic Therapy in Glioma Models

(2016) S. Y. Park et al.   MOLECULAR CANCER THERAPEUTICS

Tenascin-C Orchestrates Glioblastoma Angiogenesis by Modulation of Pro- and Anti-angiogenic Signaling

(2016) Tristan Rupp et al.   Cell Reports

A new R2-based metric to shed greater insight on variable importance in artificial neural networks

(2015) Xingli Giam et al.   ECOLOGICAL MODELLING

Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth

(2015) Wenchao Zhou et al.   NATURE CELL BIOLOGY

Deep learning in neural networks: An overview

(2015) Jürgen Schmidhuber   NEURAL NETWORKS

Tumor microenvironment tenascin-C promotes glioblastoma invasion and negatively regulates tumor proliferation

(2015) Shuli Xia et al.   NEURO-ONCOLOGY

Identification of a multi-cancer gene expression biomarker for cancer clinical outcomes using a network-based algorithm

(2015) Emmanuel Martinez-Ledesma et al.   Scientific Reports

Regularization Paths for Cox's Proportional Hazards Model via Coordinate Descent

(2015) Noah Simon et al.   Journal of Statistical Software

Activation of Multiple ERBB Family Receptors Mediates Glioblastoma Cancer Stem-like Cell Resistance to EGFR-Targeted Inhibition

(2015) Paul A. Clark et al.   NEOPLASIA

Brevican knockdown reduces late-stage glioma tumor aggressiveness

(2014) Chrissa A. Dwyer et al.   JOURNAL OF NEURO-ONCOLOGY

Periostin is a novel therapeutic target that predicts and regulates glioma malignancy

(2014) Andrei M. Mikheev et al.   NEURO-ONCOLOGY

A modified adaptive Lasso for identifying interactions in the Cox model with the heredity constraint

(2014) Lu Wang et al.   STATISTICS & PROBABILITY LETTERS

The Somatic Genomic Landscape of Glioblastoma

(2013) Cameron W. Brennan et al.   CELL

Feature selection and survival modeling in The Cancer Genome Atlas

(2013) Hyunsoo Kim et al.   International Journal of Nanomedicine

Identification of prognostic gene signatures of glioblastoma: a study based on TCGA data analysis

(2013) Y.-W. Kim et al.   NEURO-ONCOLOGY

SurvExpress: An Online Biomarker Validation Tool and Database for Cancer Gene Expression Data Using Survival Analysis

(2013) Raul Aguirre-Gamboa et al.   PLoS One

Patient-Specific Orthotopic Glioblastoma Xenograft Models Recapitulate the Histopathology and Biology of Human Glioblastomas In Situ

(2013) Kyeung Min Joo et al.   Cell Reports

The role of brevican in glioma: promoting tumor cell motility in vitro and in vivo

(2012) Renquan Lu et al.   BMC CANCER

Tenascin-R: Role in the central nervous system

(2012) Banu Anlar et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Alpha-secretase inhibition reduces human glioblastoma stem cell growth in vitro and in vivo by inhibiting Notch

(2012) Desiree H. Floyd et al.   NEURO-ONCOLOGY

Advances in tenascin-C biology

(2011) Kim S. Midwood et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Role of YKL-40 in the Angiogenesis, Radioresistance, and Progression of Glioblastoma

(2011) Ralph A. Francescone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of ELAVL4 as a modulator of radiation sensitivity in A549 non-small cell lung cancer cells

(2011) Sangwoo Bae   ONCOLOGY REPORTS

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Secreted PLA2 induces proliferation in astrocytoma through the EGF receptor: another inflammation-cancer link

(2010) M. Hernandez et al.   NEURO-ONCOLOGY

KIAA0510, the 3′-untranslated region of the tenascin-R gene, and tenascin-R are overexpressed in pilocytic astrocytomas

(2010) I. El Ayachi et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Intrinsic Gene Expression Profiles of Gliomas Are a Better Predictor of Survival than Histology

(2009) L. A.M. Gravendeel et al.   CANCER RESEARCH

Differential regulation of human thymosin beta 15 isoforms by transforming growth factor beta 1

(2009) Jacqueline Banyard et al.   GENES CHROMOSOMES & CANCER

Gene expression analysis of glioblastomas identifies the major molecular basis for the prognostic benefit of younger age

(2008) Yohan Lee et al.   BMC Medical Genomics

Stem Cell–Related “Self-Renewal” Signature and High Epidermal Growth Factor Receptor Expression Associated With Resistance to Concomitant Chemoradiotherapy in Glioblastoma

(2008) Anastasia Murat et al.   JOURNAL OF CLINICAL ONCOLOGY