Honokiol Eliminates Glioma/Glioblastoma Stem Cell-Like Cells Via JAK-STAT3 Signaling and Inhibits Tumor Progression by Targeting Epidermal Growth Factor Receptor

A fragment of adhesion molecule L1 is imported into mitochondria, and regulates mitochondrial metabolism and trafficking

(2018) Kristina Kraus et al.   JOURNAL OF CELL SCIENCE

Honokiol enhances temozolomide-induced apoptotic insults to malignant glioma cells via an intrinsic mitochondrion-dependent pathway

(2018) Chung-Ching Chio et al.   PHYTOMEDICINE

Recognition by natural killer cells of N6-isopentenyladenosine-treated human glioma cell lines

(2017) Elena Ciaglia et al.   INTERNATIONAL JOURNAL OF CANCER

Apoptosis in human liver carcinoma caused by gold nanoparticles in combination with carvedilol is mediated via modulation of MAPK/Akt/mTOR pathway and EGFR/FAAD proteins

(2017) Raimundo De Ara�jo Jr et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Honokiol induces autophagy of neuroblastoma cells through activating the PI3K/Akt/mTOR and endoplasmic reticular stress/ERK1/2 signaling pathways and suppressing cell migration

(2016) Poh-Shiow Yeh et al.   CANCER LETTERS

E-Cadherin repression increases amount of cancer stem cells in human A549 lung adenocarcinoma and stimulates tumor growth

(2016) M. Farmakovskaya et al.   CELL CYCLE

Tim-3 facilitates osteosarcoma proliferation and metastasis through the NF-κB pathway and epithelial-mesenchymal transition

(2016) Z.M. Feng et al.   GENETICS AND MOLECULAR RESEARCH

Molecular mechanisms of cell death in intervertebral disc degeneration (Review)

(2016) FAN ZHANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Osthole Protects Bone Marrow-Derived Neural Stem Cells from Oxidative Damage through PI3K/Akt-1 Pathway

(2016) Yu-hui Yan et al.   NEUROCHEMICAL RESEARCH

Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism

(2016) Josiah Gerdts et al.   NEURON

Development of Resistance to EGFR-Targeted Therapy in Malignant Glioma Can Occur through EGFR-Dependent and -Independent Mechanisms

(2015) S. Klingler et al.   CANCER RESEARCH

Zebrafish xenotransplantation as a tool for in vivo cancer study

(2015) Beibei Zhang et al.   Familial Cancer

Small Molecule Agonists of Cell Adhesion Molecule L1 Mimic L1 Functions In Vivo

(2015) Hardeep Kataria et al.   MOLECULAR NEUROBIOLOGY

MMP2 and MMP9 as candidate biomarkers to monitor bevacizumab therapy in high-grade glioma

(2015) Emeline Tabouret et al.   NEURO-ONCOLOGY

Elimination of Cancer Stem-Like Cells and Potentiation of Temozolomide Sensitivity by Honokiol in Glioblastoma Multiforme Cells

(2015) I-Chun Lai et al.   PLoS One

Podoplanin-Positive Cancer-Associated Fibroblasts in the Tumor Microenvironment Induce Primary Resistance to EGFR-TKIs in Lung Adenocarcinoma with EGFR Mutation

(2014) Tatsuya Yoshida et al.   CLINICAL CANCER RESEARCH

Expression of survivin and p53 modulates honokiol-induced apoptosis in colorectal cancer cells

(2014) Ying-Jiun Lai et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Conditional probability of survival and post-progression survival in patients with glioblastoma in the temozolomide treatment era

(2014) Mairéad G. McNamara et al.   JOURNAL OF NEURO-ONCOLOGY

Honokiol inhibits melanoma stem cells by targeting notch signaling

(2014) Gaurav Kaushik et al.   MOLECULAR CARCINOGENESIS

Effect of Acute Stresses on Zebra Fish (Danio rerio) Metabolome Measured by NMR-Based Metabolomics

(2014) Mian Mushtaq et al.   PLANTA MEDICA

Honokiol Enhances Paclitaxel Efficacy in Multi-Drug Resistant Human Cancer Model through the Induction of Apoptosis

(2014) Xu Wang et al.   PLoS One

Rab40b regulates trafficking of MMP2 and MMP9 during invadopodia formation and invasion of breast cancer cells

(2013) A. Jacob et al.   JOURNAL OF CELL SCIENCE

Neuregulin 1 Enhances Cell Adhesion Molecule L1 Expression in Human Glioma Cells and Promotes Their Migration as a Function of Malignancy

(2013) Wei-Jiang Zhao et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Cooperativity between MAPK and PI3K signaling activation is required for glioblastoma pathogenesis

(2013) M. Vitucci et al.   NEURO-ONCOLOGY

Honokiol exerts an anticancer effect in T98G human glioblastoma cells through the induction of apoptosis and the regulation of adhesion molecules

(2012) JAE JU JEONG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Tumor-Associated Macrophages Regulate Murine Breast Cancer Stem Cells Through a Novel Paracrine EGFR/Stat3/Sox-2 Signaling Pathway

(2012) Jian Yang et al.   STEM CELLS

Ligand-dependent EGFR activation induces the co-expression of IL-6 and PAI-1 via the NFkB pathway in advanced-stage epithelial ovarian cancer

(2011) C Alberti et al.   ONCOGENE

Honokiol, a Multifunctional Antiangiogenic and Antitumor Agent

(2009) Levi E. Fried et al.   ANTIOXIDANTS & REDOX SIGNALING

Glioma Stem Cells: Better Flat Than Round

(2009) Kevin Woolard et al.   Cell Stem Cell

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE