Versatile Prodrug Nanoparticles for Acid-Triggered Precise Imaging and Organelle-Specific Combination Cancer Therapy

Intracellularly Acid-Switchable Multifunctional Micelles for Combinational Photo/Chemotherapy of the Drug-Resistant Tumor

(2016) Tingting Wang et al.   ACS Nano

Long Circulation Red-Blood-Cell-Mimetic Nanoparticles with Peptide-Enhanced Tumor Penetration for Simultaneously Inhibiting Growth and Lung Metastasis of Breast Cancer

(2016) Jinghan Su et al.   ADVANCED FUNCTIONAL MATERIALS

A Smart Photosensitizer-Manganese Dioxide Nanosystem for Enhanced Photodynamic Therapy by Reducing Glutathione Levels in Cancer Cells

(2016) Huanhuan Fan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A photoactivable multi-inhibitor nanoliposome for tumour control and simultaneous inhibition of treatment escape pathways

(2016) Bryan Q. Spring et al.   Nature Nanotechnology

Stimuli-responsive clustered nanoparticles for improved tumor penetration and therapeutic efficacy

(2016) Hong-Jun Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Triple-Layered pH-Responsive Micelleplexes Loaded with siRNA and Cisplatin Prodrug for NF-Kappa B Targeted Treatment of Metastatic Breast Cancer

(2016) Haijun Yu et al.   Theranostics

Cisplatin Prodrug-Conjugated Gold Nanocluster for Fluorescence Imaging and Targeted Therapy of the Breast Cancer

(2016) Fangyuan Zhou et al.   Theranostics

“Triple-Punch” Strategy for Triple Negative Breast Cancer Therapy with Minimized Drug Dosage and Improved Antitumor Efficacy

(2015) Shishuai Su et al.   ACS Nano

Multipronged Design of Light-Triggered Nanoparticles To Overcome Cisplatin Resistance for Efficient Ablation of Resistant Tumor

(2015) Yanli Li et al.   ACS Nano

Ratiometric Biosensor for Aggregation-Induced Emission-Guided Precise Photodynamic Therapy

(2015) Kai Han et al.   ACS Nano

Self-Assembled Core–Shell Nanoparticles for Combined Chemotherapy and Photodynamic Therapy of Resistant Head and Neck Cancers

(2015) Chunbai He et al.   ACS Nano

Reversal of doxorubicin resistance in breast cancer by mitochondria-targeted pH-responsive micelles

(2015) Pengcheng Yu et al.   Acta Biomaterialia

A Peptide-Network Weaved Nanoplatform with Tumor Microenvironment Responsiveness and Deep Tissue Penetration Capability for Cancer Therapy

(2015) Ya Liu et al.   ADVANCED MATERIALS

Fusogenic Reactive Oxygen Species Triggered Charge-Reversal Vector for Effective Gene Delivery

(2015) Xin Liu et al.   ADVANCED MATERIALS

Hypoxia Induced by Upconversion-Based Photodynamic Therapy: Towards Highly Effective Synergistic Bioreductive Therapy in Tumors

(2015) Yanyan Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancer

(2015) Yubao Wang et al.   CELL

Glycosylated Porphyrins, Phthalocyanines, and Other Porphyrinoids for Diagnostics and Therapeutics

(2015) Sunaina Singh et al.   CHEMICAL REVIEWS

Molecular Interactions in Organic Nanoparticles for Phototheranostic Applications

(2015) Kenneth K. Ng et al.   CHEMICAL REVIEWS

Multimodal Image-Guided Surgical and Photodynamic Interventions in Head and Neck Cancer: From Primary Tumor to Metastatic Drainage

(2015) N. Muhanna et al.   CLINICAL CANCER RESEARCH

Tumor Acidity-Sensitive Polymeric Vector for Active Targeted siRNA Delivery

(2015) Chun-Yang Sun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Near infrared light-actuated gold nanorods with cisplatin–polypeptide wrapping for targeted therapy of triple negative breast cancer

(2015) Bing Feng et al.   Nanoscale

A Multifunctional Nanomicelle for Real-Time Targeted Imaging and Precise Near-Infrared Cancer Therapy

(2014) Jiangwei Tian et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanomaterials for Theranostics: Recent Advances and Future Challenges

(2014) Eun-Kyung Lim et al.   CHEMICAL REVIEWS

Capecitabine and Oxaliplatin in the Preoperative Multimodality Treatment of Rectal Cancer: Surgical End Points From National Surgical Adjuvant Breast and Bowel Project Trial R-04

(2014) Michael J. O'Connell et al.   JOURNAL OF CLINICAL ONCOLOGY

Pt(IV) Prodrugs Designed to Bind Non-Covalently to Human Serum Albumin for Drug Delivery

(2014) Yao-Rong Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Layer-by-Layer Nanoparticles for Systemic Codelivery of an Anticancer Drug and siRNA for Potential Triple-Negative Breast Cancer Treatment

(2013) Zhou J. Deng et al.   ACS Nano

Photothermally Triggered Cytosolic Drug Delivery via Endosome Disruption Using a Functionalized Reduced Graphene Oxide

(2013) Hyunwoo Kim et al.   ACS Nano

Imaging-Guided pH-Sensitive Photodynamic Therapy Using Charge Reversible Upconversion Nanoparticles under Near-Infrared Light

(2013) Chao Wang et al.   ADVANCED FUNCTIONAL MATERIALS

Polyion Complex Vesicles for Photoinduced Intracellular Delivery of Amphiphilic Photosensitizer

(2013) Huabing Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cell-Specific and pH-Activatable Rubyrin-Loaded Nanoparticles for Highly Selective Near-Infrared Photodynamic Therapy against Cancer

(2013) Jiangwei Tian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reversal of Multidrug Resistance by Mitochondrial Targeted Self-Assembled Nanocarrier Based on Stearylamine

(2013) Zhiwen Zhang et al.   MOLECULAR PHARMACEUTICS

Functionalized Nanoscale Micelles Improve Drug Delivery for Cancer Therapy in Vitro and in Vivo

(2013) Tuo Wei et al.   NANO LETTERS

A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals

(2013) Yiguang Wang et al.   NATURE MATERIALS

Intracellular pH-activated PEG-b-PDPA wormlike micelles for hydrophobic drug delivery

(2013) Haijun Yu et al.   Polymer Chemistry

Tumor-targeting hyaluronic acid nanoparticles for photodynamic imaging and therapy

(2012) Hong Yeol Yoon et al.   BIOMATERIALS

Targeting and delivery of platinum-based anticancer drugs

(2012) Xiaoyong Wang et al.   CHEMICAL SOCIETY REVIEWS

Co-delivery of daunomycin and oxaliplatin by biodegradable polymers for safer and more efficacious combination therapy

(2012) Haihua Xiao et al.   JOURNAL OF CONTROLLED RELEASE

Theranostic Nanoparticles Engineered for Clinic and Pharmaceutics

(2011) Xiaowei Ma et al.   ACCOUNTS OF CHEMICAL RESEARCH

Overcoming Endosomal Barrier by Amphotericin B-Loaded Dual pH-Responsive PDMA-b-PDPA Micelleplexes for siRNA Delivery

(2011) Haijun Yu et al.   ACS Nano

Tunable, Ultrasensitive pH-Responsive Nanoparticles Targeting Specific Endocytic Organelles in Living Cells

(2011) Kejin Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Near-Infrared pH-Activatable Fluorescent Probes for Imaging Primary and Metastatic Breast Tumors

(2011) Hyeran Lee et al.   BIOCONJUGATE CHEMISTRY

Improving Drug Potency and Efficacy by Nanocarrier-Mediated Subcellular Targeting

(2011) M. Murakami et al.   Science Translational Medicine

Activatable Photosensitizers for Imaging and Therapy

(2010) Jonathan F. Lovell et al.   CHEMICAL REVIEWS

Targeting mitochondria for cancer therapy

(2010) Simone Fulda et al.   NATURE REVIEWS DRUG DISCOVERY

Coadministration of a Tumor-Penetrating Peptide Enhances the Efficacy of Cancer Drugs

(2010) K. N. Sugahara et al.   SCIENCE

Subcellular targeting strategies for drug design and delivery

(2009) Lawrence Rajendran et al.   NATURE REVIEWS DRUG DISCOVERY

Chlorin e6-based photosensitizers for photodynamic therapy and photodiagnosis

(2009) Asta Juzeniene   Photodiagnosis and Photodynamic Therapy

Targeted Single-Wall Carbon Nanotube-Mediated Pt(IV) Prodrug Delivery Using Folate as a Homing Device

(2008) Shanta Dhar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY