Characterization of the Apelin/Elabela Receptors (APLNR) in Chickens, Turtles, and Zebrafish: Identification of a Novel Apelin-Specific Receptor in Teleosts

The orphan G protein-coupled receptor 25 (GPR25) is activated by Apelin and Apela in non-mammalian vertebrates

(2018) Jiannan Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Characterization of neuromedin U (NMU), neuromedin S (NMS) and their receptors (NMUR1, NMUR2) in chickens

(2018) Yiping Wan et al.   PEPTIDES

Characterization of NMB, GRP and their receptors (BRS3, NMBR and GRPR) in chickens

(2017) Chunheng Mo et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

ELABELA deficiency promotes preeclampsia and cardiovascular malformations in mice

(2017) Lena Ho et al.   SCIENCE

Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives

(2017) Laina Freyer et al.   Cell Reports

Characterization of Neuropeptide B (NPB), Neuropeptide W (NPW), and Their Receptors in Chickens: Evidence for NPW Being a Novel Inhibitor of Pituitary GH and Prolactin Secretion

(2016) Guixian Bu et al.   ENDOCRINOLOGY

ELABELA Is an Endogenous Growth Factor that Sustains hESC Self-Renewal via the PI3K/AKT Pathway

(2015) Lena Ho et al.   Cell Stem Cell

Apela Regulates Fluid Homeostasis by Binding to the APJ Receptor to Activate Gi Signaling

(2015) Cheng Deng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of the Two CART Genes (CART1 and CART2) in Chickens (Gallus gallus)

(2015) Guoqing Cai et al.   PLoS One

Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular system

(2015) Peiran Yang et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The hormonal peptide Elabela guides angioblasts to the midline during vasculogenesis

(2015) Christian SM Helker et al.   eLife

Apelin and energy metabolism

(2015) Chantal Bertrand et al.   Frontiers in Physiology

Elabela-Apelin Receptor Signaling Pathway is Functional in Mammalian Systems

(2015) Zhi Wang et al.   Scientific Reports

Adiponectin/T-cadherin and apelin/APJ expression in human arteries and periadventitial fat: implication of local adipokine signaling in atherosclerosis?

(2014) Christos G. Kostopoulos et al.   CARDIOVASCULAR PATHOLOGY

Glucagon-Like Peptide (GCGL) Is a Novel Potential TSH-Releasing Factor (TRF) in Chickens: I) Evidence for Its Potent and Specific Action on Stimulating TSH mRNA Expression and Secretion in the Pituitary

(2014) Guian Huang et al.   ENDOCRINOLOGY

Identification of Serine 348 on the Apelin Receptor as a Novel Regulatory Phosphorylation Site in Apelin-13-induced G Protein-independent Biased Signaling

(2014) Xiaoyu Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of the receptors for somatostatin (SST) and cortistatin (CST) in chickens and investigation of the roles of cSST28, cSST14, and cCST14 in inhibiting cGHRH1–27NH2-induced growth hormone secretion in cultured chicken pituitary cells

(2014) Fengyan Meng et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Toddler: An Embryonic Signal That Promotes Cell Movement via Apelin Receptors

(2014) A. Pauli et al.   SCIENCE

Apelin-APJ Signaling Is a Critical Regulator of Endothelial MEF2 Activation in Cardiovascular Development

(2013) Yujung Kang et al.   CIRCULATION RESEARCH

ELABELA: A Hormone Essential for Heart Development Signals via the Apelin Receptor

(2013) Serene C. Chng et al.   DEVELOPMENTAL CELL

Peripheral injections of cholecystokinin, apelin, ghrelin and orexin in cavefish (Astyanax fasciatus mexicanus): Effects on feeding and on the brain expression levels of tyrosine hydroxylase, mechanistic target of rapamycin and appetite-related hormones

(2013) Carla C. Penney et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

The apelin receptor APJ: journey from an orphan to a multifaceted regulator of homeostasis

(2013) Anne-Marie O'Carroll et al.   JOURNAL OF ENDOCRINOLOGY

Apelin Enhances Cardiac Neovascularization After Myocardial Infarction by Recruiting Aplnr+ Circulating Cells

(2012) Dennie Tempel et al.   CIRCULATION RESEARCH

Neuroprotection of apelin and its signaling pathway

(2012) Baohua Cheng et al.   PEPTIDES

The Aplnr GPCR regulates myocardial progenitor development via a novel cell-non-autonomous, G i/o protein-independent pathway

(2012) S. Paskaradevan et al.   Biology Open

Central apelin-13 inhibits food intake via the CRF receptor in mice

(2011) Shuang-Yu Lv et al.   PEPTIDES

International Union of Basic and Clinical Pharmacology. LXXIV. Apelin Receptor Nomenclature, Distribution, Pharmacology, and Function

(2010) S. L. Pitkin et al.   PHARMACOLOGICAL REVIEWS

Endogenous regulation of cardiovascular function by apelin-APJ

(2009) David N. Charo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

G Protein-Coupled Receptor APJ and Its Ligand Apelin Act Downstream of Cripto to Specify Embryonic Stem Cells Toward the Cardiac Lineage Through Extracellular Signal-Regulated Kinase/p70S6 Kinase Signaling Pathway

(2009) Cristina D'Aniello et al.   CIRCULATION RESEARCH

[Pyr 1 ]Apelin-13 Identified as the Predominant Apelin Isoform in the Human Heart

(2009) Janet J. Maguire et al.   HYPERTENSION

The effects of apelin on hypothalamic–pituitary–adrenal axis neuroendocrine function are mediated through corticotrophin-releasing factor- and vasopressin-dependent mechanisms

(2009) Michael J F Newson et al.   JOURNAL OF ENDOCRINOLOGY

Apelin in goldfish (Carassius auratus): Cloning, distribution and role in appetite regulation

(2009) Hélène Volkoff et al.   PEPTIDES