Molecular inflation, attrition and the rule of five

Published 2016 View Full Article

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Title
Molecular inflation, attrition and the rule of five
Authors
Keywords
Physicochemical properties, Risk/benefit, Patented compounds, Impact of time, Lipophilic ligand efficiency, Exception space, Lead optimisation, Compound quality
Journal
ADVANCED DRUG DELIVERY REVIEWS
Volume 101, Issue -, Pages 22-33
Publisher
Elsevier BV
Online
2016-02-01
DOI
10.1016/j.addr.2016.01.018

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