Article
Clinical Neurology
Georgios Tsivgoulis, Aristeidis H. Katsanos, Jurgen Eggers, Vincent Larrue, Lars Thomassen, James C. Grotta, Georgios Seitidis, Peter D. Schellinger, Dimitris Mavridis, Andrew Demchuk, Vojtech Novotny, Carlos A. Molina, Areti Angeliki Veroniki, Martin Kohrmann, Lauri Soinne, Andrej Netland Khanevski, Andrew D. Barreto, Maher Saqqur, Theodora Psaltopoulou, Keith W. Muir, Jochen B. Fiebach, Travis Rothlisberger, Thomas A. Kent, Pitchaiah Mandava, Anne W. Alexandrov, Andrei Alexandrov
Summary: This study evaluated the safety and efficacy of sonothrombolysis in patients with acute ischemic stroke and large vessel occlusion, showing that sonothrombolysis was associated with a nearly 2-fold increase in the odds of complete recanalization compared with intravenous thrombolysis alone. Further research on the safety and efficacy of sonothrombolysis is needed.
Article
Oncology
Huijun Wang, Li Fei, Hongbo Xia, Qian Zhang, Youping Huang
Summary: The study found that the combination of TCD with CU in the diagnosis of CIS has higher accuracy, sensitivity, and specificity, which can improve the diagnostic efficiency and provide more evidence for clinical therapy.
AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH
(2021)
Review
Endocrinology & Metabolism
Jui-Lin Fan, Ricardo C. Nogueira, Patrice Brassard, Caroline A. Rickards, Matthew Page, Nathalie Nasr, Yu-Chieh Tzeng
Summary: This article discusses the importance of reperfusion treatment in acute ischemic stroke patients and highlights the impact of blood pressure on cerebral perfusion. It emphasizes the importance of effective blood pressure management in the early stages of stroke, and suggests that bedside monitoring of cerebral perfusion and oxygenation can help guide treatment and improve outcomes.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
(2022)
Article
Clinical Neurology
Paulina B. Sergot, Andrew J. Maza, Bruce J. Derrick, Lane M. Smith, Liam T. Berti, Madeleine R. Wilcox, Matthew R. Kesinger, W. Frank Peacock
Summary: The study investigated a portable LVO-detection device (PLD) using electroencephalography and somatosensory-evoked potentials to identify LVO stroke with superior accuracy and discrimination compared to prehospital stroke scales. Future research is needed to validate the potential of PLD as an LVO triage aid in prehospital undifferentiated stroke populations.
Article
Chemistry, Multidisciplinary
Marcin Sawicki, Krzysztof Safranow, Lidia Wiska, Igor Pasek, Aleksandra Gajdziel, Michal Gruszewski, Wojciech Poncyljusz
Summary: The study found that the AI-based software performed well in detecting proximal large vessel occlusions but showed lower accuracy in detecting distal occlusions.
APPLIED SCIENCES-BASEL
(2021)
Review
Neurosciences
Jiecheng Guo, Wai Leung Ambrose Lo, Huijing Hu, Li Yan, Le Li
Summary: Ischemic stroke is a serious condition caused by cerebral vascular occlusion, leading to neurological dysfunction. Transcranial ultrasound stimulation (TUS) is a promising non-invasive technique for the treatment of ischemic stroke. TUS can induce mechanical and thermal effects by delivering sound waves, reducing cell apoptosis and inflammation, and can also dissolve blood clots and deliver therapeutic drugs to the ischemic region.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Clinical Neurology
Isabelle Crassard, Karine Berthet, Philippa Lavallee, Marion Houot, Didier Payen, Jean-Claude Baron, Pierre Amarenco, Anne-Claire Lukaszewicz
Summary: This study analyzed the effects of LBPP on cerebral blood flow velocities in patients with recently symptomatic isolated carotid occlusion/tight stenosis. The results showed that LBPP significantly improved blood flow velocities in the affected and unaffected middle cerebral artery as well as the basilar artery.
INTERNATIONAL JOURNAL OF STROKE
(2022)
Article
Neurosciences
Shuai Liu, Fengli Li, Jie Yang, Dongjie Xie, Chengsong Yue, Weidong Luo, Jinrong Hu, Jiaxing Song, Linyu Li, Jiacheng Huang, Chenhao Zhao, Zili Gong, Qingwu Yang, Wenjie Zi
Summary: This study found that combining NBP with EVT in patients with AIS due to LVO can improve functional outcomes, reduce mortality risk, and does not increase the risk of sICH.
CNS NEUROSCIENCE & THERAPEUTICS
(2022)
Review
Neurosciences
Shuiping Zhu, Bin Meng, Jianping Jiang, Xiaotao Wang, Na Luo, Ning Liu, Huaping Shen, Lu Wang, Qian Li
Summary: Ischemic stroke is a common cause of death and disability, leading to significant burdens. Transcranial ultrasound stimulation (TUS) is a non-invasive method that can dissolve thrombus, improve cerebral blood circulation, and promote functional recovery among patients with ischemic stroke.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2022)
Article
Acoustics
Rodrigo Tavares Brisson, Renata da Silva Almeida Santos, Luiz Henrique Soares Santos Stefano, Clara Monteiro Antunes Barreira, Josevania Fulgencio de Lima Arruda, Francisco Antunes Dias, Millene Rodrigues Camilo, Octavio Marques Pontes-Neto
Summary: This study found that age, female sex, pneumatized temporal bone, and temporal bone thickness are independent predictors of transcranial window failure. These findings may assist in selecting patients in whom echogenic contrast or other imaging methods could be used to assess intracranial vessels.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2021)
Article
Biology
Gabor Tarkanyi, Akos Tenyi, Roland Hollos, Peter Janos Kalmar, Laszlo Szapary
Summary: In predicting LVO, besides neurological symptoms, other variables such as atrial fibrillation, chronic heart failure, and white blood cell counts also have an impact on the predictive performance.
Article
Clinical Neurology
Gauthier Duloquin, Valentin Crespy, Pauline Jakubina, Maurice Giroud, Catherine Vergely, Yannick Bejot
Summary: The study found that minor ischemic stroke with large vessel occlusion is not uncommon, and its characteristics include severe symptom presentation, decreased consciousness, cortical signs, especially aphasia and altered item level of consciousness. Emergency arterial imaging is needed for patients suspected of acute stroke, including those with minor symptoms, due to the absence of obvious predictors of proximal occlusion.
FRONTIERS IN NEUROLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Rui Xue, Wansi Zhong, Ying Zhou, Yaode He, Shenqiang Yan, Zhicai Chen, Jianan Wang, Xiaoxian Gong, Min Lou
Summary: This study aimed to evaluate the outcomes of endovascular treatment (EVT) in patients with minor acute ischemic stroke with anterior circulation large vessel occlusion. The results showed that EVT did not improve functional outcomes in patients with minor acute ischemic stroke caused by large vessel occlusion, but EVT guided by perfusion imaging may be beneficial for these patients.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Medicine, General & Internal
Fanny Planquart, Emmanuel Marcaggi, Raiko Blondonnet, Olivier Clovet, Xavier Bobbia, Bastien Boussat, Julien Pottecher, Tobias Gauss, Laurent Zieleskiewicz, Pierre Bouzat
Summary: This cohort study aimed to determine the appropriateness of immediate actions taken in the resuscitation room for patients with blunt trauma based on a diagnostic workup that included E-FAST. The study found that the diagnostic workup, including E-FAST, clinical assessment, and targeted radiographs, was associated with the determination of an appropriate course of action prior to WBCT.
Article
Hematology
Wen-Jun Tu, Yicheng Xu, Yakun Liu, Jichen Du, Jizong Zhao
Summary: This study evaluated the efficacy of direct endovascular thrombectomy (EVT) compared to bridging therapy in patients with minor acute ischemic stroke due to large vessel occlusions (AIS-LVO). The results showed that direct EVT was comparable to bridging therapy in terms of the three-month prognosis.
THROMBOSIS RESEARCH
(2022)