Prognostic Implications of Heterogeneity in Intra-tumoral Immune Composition for Recurrence in Early Stage Lung Cancer

CD8 + T Cells Orchestrate pDC-XCR1 + Dendritic Cell Spatial and Functional Cooperativity to Optimize Priming

(2017) Anna Brewitz et al.   IMMUNITY

Neutrophils dominate the immune cell composition in non-small cell lung cancer

(2017) Julia Kargl et al.   Nature Communications

Compendium of Immune Signatures Identifies Conserved and Species-Specific Biology in Response to Inflammation

(2016) Jernej Godec et al.   IMMUNITY

Prognostic Effect of Tumor Lymphocytic Infiltration in Resectable Non–Small-Cell Lung Cancer

(2016) Elisabeth Brambilla et al.   JOURNAL OF CLINICAL ONCOLOGY

Immunoscore and Immunoprofiling in cancer: an update from the melanoma and immunotherapy bridge 2015

(2016) J. Galon et al.   Journal of Translational Medicine

Patterns of Immune Infiltration in Breast Cancer and Their Clinical Implications: A Gene-Expression-Based Retrospective Study

(2016) H. Raza Ali et al.   PLOS MEDICINE

The Non–Small Cell Lung Cancer Immune Contexture. A Major Determinant of Tumor Characteristics and Patient Outcome

(2015) Romain Remark et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Objective Measurement and Clinical Significance of TILs in Non–Small Cell Lung Cancer

(2015) Kurt A. Schalper et al.   JNCI-Journal of the National Cancer Institute

The prognostic landscape of genes and infiltrating immune cells across human cancers

(2015) Andrew J Gentles et al.   NATURE MEDICINE

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

Objective Measurement and Clinical Significance of TILs in Non–Small Cell Lung Cancer

(2015) Kurt A. Schalper et al.   JNCI-Journal of the National Cancer Institute

Dendritic Cells in Tumor-Associated Tertiary Lymphoid Structures Signal a Th1 Cytotoxic Immune Contexture and License the Positive Prognostic Value of Infiltrating CD8+ T Cells

(2013) J. Goc et al.   CANCER RESEARCH

Validation of a Histology-Independent Prognostic Gene Signature for Early-Stage, Non–Small-Cell Lung Cancer Including Stage IA Patients

(2013) Sandy D. Der et al.   Journal of Thoracic Oncology

Local recurrence following lung cancer surgery: Incidence, risk factors, and outcomes

(2013) David Fedor et al.   SURGICAL ONCOLOGY-OXFORD

Biomarker Discovery in Non-Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation

(2012) J. Botling et al.   CLINICAL CANCER RESEARCH

A Comprehensive Analysis of Human Gene Expression Profiles Identifies Stromal Immunoglobulin   C as a Compatible Prognostic Marker in Human Solid Tumors

(2012) M. Schmidt et al.   CLINICAL CANCER RESEARCH

Clinical Impact of Immune Microenvironment in Stage I Lung Adenocarcinoma: Tumor Interleukin-12 Receptor β2 (IL-12Rβ2), IL-7R, and Stromal FoxP3/CD3 Ratio Are Independent Predictors of Recurrence

(2012) Kei Suzuki et al.   JOURNAL OF CLINICAL ONCOLOGY

inSilicoDb: an R/Bioconductor package for accessing human Affymetrix expert-curated datasets from GEO

(2011) J. Taminau et al.   BIOINFORMATICS

Assessing affymetrix GeneChip microarray quality

(2011) Matthew N McCall et al.   BMC BIOINFORMATICS

Increased Levels of Tumor-Infiltrating Lymphocytes are Associated with Improved Recurrence-Free Survival in Stage 1A Non-Small-Cell Lung Cancer

(2011) Zachary D. Horne et al.   JOURNAL OF SURGICAL RESEARCH

Prognostic potential of FOXP3 expression in non-small cell lung cancer cells combined with tumor-infiltrating regulatory T cells

(2011) Hiroyuki Tao et al.   LUNG CANCER

Local and Systemic Recurrence is the Achilles Heel of Cancer Surgery

(2010) Louis A. Aliperti et al.   ANNALS OF SURGICAL ONCOLOGY

Tumor-Infiltrating Foxp3+ Regulatory T Cells are Correlated with Cyclooxygenase-2 Expression and are Associated with Recurrence in Resected Non-small Cell Lung Cancer

(2010) Katsuhiko Shimizu et al.   Journal of Thoracic Oncology

A human functional protein interaction network and its application to cancer data analysis

(2010) Guanming Wu et al.   GENOME BIOLOGY

The New Lung Cancer Staging System

(2009) Frank C. Detterbeck et al.   CHEST

Selective Expression of the Chemokine Receptor XCR1 on Cross-presenting Dendritic Cells Determines Cooperation with CD8+ T Cells

(2009) Brigitte G. Dorner et al.   IMMUNITY

Density of Tumor-Infiltrating Lymphocytes Correlates with Disease Recurrence and Survival in Patients with Large Non-Small-Cell Lung Cancer Tumors

(2009) Arman Kilic et al.   JOURNAL OF SURGICAL RESEARCH

Predominant infiltration of macrophages and CD8+T Cells in cancer nests is a significant predictor of survival in stage IV nonsmall cell lung cancer

(2008) Osamu Kawai et al.   CANCER

Prognostic Effect of Epithelial and Stromal Lymphocyte Infiltration in Non-Small Cell Lung Cancer

(2008) K. I. Al-Shibli et al.   CLINICAL CANCER RESEARCH

Gene expression–based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study

(2008) Kerby Shedden et al.   NATURE MEDICINE