Long-Lived Plasma Cells in Mice and Men

No strict requirement for eosinophils for bone marrow plasma cell survival

(2018) Alexandra Bortnick et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Antibody-secreting plasma cells persist for decades in human intestine

(2017) Ole J.B. Landsverk et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Here, There, and Anywhere? Arguments for and against the Physical Plasma Cell Survival Niche

(2017) Joel R. Wilmore et al.   JOURNAL OF IMMUNOLOGY

T Regulatory Cells Support Plasma Cell Populations in the Bone Marrow

(2017) Arielle Glatman Zaretsky et al.   Cell Reports

Phase 2 study of tabalumab, a human anti-B-cell activating factor antibody, with bortezomib and dexamethasone in patients with previously treated multiple myeloma

(2016) Noopur S. Raje et al.   BRITISH JOURNAL OF HAEMATOLOGY

Forced KLF4 expression increases the generation of mature plasma cells and uncovers a network linked with plasma cell stage

(2016) Matthieu Schoenhals et al.   CELL CYCLE

Phase 1 Study of Tabalumab, a Human Anti-B-Cell Activating Factor Antibody, and Bortezomib in Patients with Relapsed/Refractory Multiple Myeloma

(2016) N. S. Raje et al.   CLINICAL CANCER RESEARCH

Bone marrow fat and the decline of B lymphopoiesis in rabbits

(2016) Domenick E. Kennedy et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Blimp-1 controls plasma cell function through the regulation of immunoglobulin secretion and the unfolded protein response

(2016) Julie Tellier et al.   NATURE IMMUNOLOGY

Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation

(2016) Martina Minnich et al.   NATURE IMMUNOLOGY

Temporal stability and molecular persistence of the bone marrow plasma cell antibody repertoire

(2016) Gabriel C. Wu et al.   Nature Communications

Mature IgM-expressing plasma cells sense antigen and develop competence for cytokine production upon antigenic challenge

(2016) Pascal Blanc et al.   Nature Communications

Limited clonal relatedness between gut IgA plasma cells and memory B cells after oral immunization

(2016) Mats Bemark et al.   Nature Communications

The proteasome inhibitior bortezomib depletes plasma cells and ameliorates clinical manifestations of refractory systemic lupus erythematosus

(2015) Tobias Alexander et al.   ANNALS OF THE RHEUMATIC DISEASES

A unique population of IgG-expressing plasma cells lacking CD19 is enriched in human bone marrow

(2015) H. E. Mei et al.   BLOOD

Long-Lived Plasma Cells Are Contained within the CD19−CD38hiCD138+ Subset in Human Bone Marrow

(2015) Jessica L. Halliley et al.   IMMUNITY

IgG4-related disease

(2015) Terumi Kamisawa et al.   LANCET

Long-lived plasma cells are generated in mucosal immune responses and contribute to the bone marrow plasma cell pool in mice

(2015) A Lemke et al.   Mucosal Immunology

Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells

(2015) Wei Shi et al.   NATURE IMMUNOLOGY

Region-specific variation in the properties of skeletal adipocytes reveals regulated and constitutive marrow adipose tissues

(2015) Erica L. Scheller et al.   Nature Communications

International Consensus Guidance Statement on the Management and Treatment of IgG4-Related Disease

(2015) A. Khosroshahi et al.   Arthritis & Rheumatology

Efficacy and safety of atacicept for prevention of flares in patients with moderate-to-severe systemic lupus erythematosus (SLE): 52-week data (APRIL-SLE randomised trial)

(2014) David Isenberg et al.   ANNALS OF THE RHEUMATIC DISEASES

Early-Onset Type 2 Diabetes Impairs Skeletal Acquisition in the Male TALLYHO/JngJ Mouse

(2014) M. J. Devlin et al.   ENDOCRINOLOGY

Eosinophils Promote Generation and Maintenance of Immunoglobulin-A-Expressing Plasma Cells and Contribute to Gut Immune Homeostasis

(2014) Van Trung Chu et al.   IMMUNITY

Cutting Edge: The Dependence of Plasma Cells and Independence of Memory B Cells on BAFF and APRIL

(2014) M. J. Benson et al.   JOURNAL OF IMMUNOLOGY

IL-6 supports the generation of human long-lived plasma cells in combination with either APRIL or stromal cell-soluble factors

(2014) M Jourdan et al.   LEUKEMIA

A functional BCR in human IgA and IgM plasma cells

(2013) D. Pinto et al.   BLOOD

Mice as a Mammalian Model for Research on the Genetics of Aging

(2013) R. Yuan et al.   ILAR JOURNAL

Interleukin 5 immunotherapy depletes alloreactive plasma cells

(2013) Robert R. Redfield et al.   JOURNAL OF SURGICAL RESEARCH

Targeting eosinophils in allergy, inflammation and beyond

(2013) Patricia C. Fulkerson et al.   NATURE REVIEWS DRUG DISCOVERY

Belimumab reduces autoantibodies, normalizes low complement levels, and reduces select B cell populations in patients with systemic lupus erythematosus

(2012) William Stohl et al.   ARTHRITIS AND RHEUMATISM

Homing and Adhesion Patterns Determine the Cellular Composition of the Bone Marrow Plasma Cell Niche

(2012) E. Belnoue et al.   JOURNAL OF IMMUNOLOGY

Long-Lived Bone Marrow Plasma Cells Are Induced Early in Response to T Cell-Independent or T Cell-Dependent Antigens

(2012) A. Bortnick et al.   JOURNAL OF IMMUNOLOGY

Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial

(2012) Ian D Pavord et al.   LANCET

Alternate pathways for Bcl6-mediated regulation of B cell to plasma cell differentiation

(2011) Jukka Alinikula et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Changes in human bone marrow fat content associated with changes in hematopoietic stem cell numbers and cytokine levels with aging

(2011) Sonal R. Tuljapurkar et al.   JOURNAL OF ANATOMY

Eosinophils are required for the maintenance of plasma cells in the bone marrow

(2011) Van Trung Chu et al.   NATURE IMMUNOLOGY

Safety, immunogenicity and kinetics of immune response to 7-valent pneumococcal conjugate vaccine in children with idiopathic nephrotic syndrome

(2011) Christina D. Liakou et al.   VACCINE

Megakaryocytes constitute a functional component of a plasma cell niche in the bone marrow

(2010) O. Winter et al.   BLOOD

Mechanisms that determine plasma cell lifespan and the duration of humoral immunity

(2010) Ian J. Amanna et al.   IMMUNOLOGICAL REVIEWS

Basophils Support the Survival of Plasma Cells in Mice

(2010) M. R. Gomez et al.   JOURNAL OF IMMUNOLOGY

Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation

(2010) Shane Crotty et al.   NATURE IMMUNOLOGY

XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells

(2009) Chih-Chi Andrew Hu et al.   EMBO JOURNAL