Deficient O-GlcNAc Glycosylation Impairs Regulatory T Cell Differentiation and Notch Signaling in Autoimmune Hepatitis

O-GlcNAc on NOTCH1 EGF repeats regulates ligand-induced Notch signaling and vascular development in mammals

(2017) Shogo Sawaguchi et al.   eLife

Distinctive Surface Glycosylation Patterns Associated With Mouse and Human CD4+ Regulatory T Cells and Their Suppressive Function

(2017) Joana Cabral et al.   Frontiers in Immunology

The concanavalin A model of acute hepatitis in mice

(2015) F Heymann et al.   LABORATORY ANIMALS

Control of peripheral tolerance by regulatory T cell–intrinsic Notch signaling

(2015) Louis-Marie Charbonnier et al.   NATURE IMMUNOLOGY

Significance of glycosylation in Notch signaling

(2014) Hideyuki Takeuchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hepatic Immune Regulation and Its Involvement in Viral Hepatitis Infection

(2014) Percy A. Knolle et al.   GASTROENTEROLOGY

Regulatory T cells and autoimmune hepatitis: What happens in the liver stays in the liver

(2014) Ye H. Oo et al.   JOURNAL OF HEPATOLOGY

TGF-β-dependent induction of CD4+CD25+Foxp3+ Tregs by liver sinusoidal endothelial cells

(2014) Antonella Carambia et al.   JOURNAL OF HEPATOLOGY

Intrahepatic regulatory T cells in autoimmune hepatitis are associated with treatment response and depleted with current therapies

(2014) Richard Taubert et al.   JOURNAL OF HEPATOLOGY

Notch1 Signaling and Regulatory T Cell Function

(2014) N. Asano et al.   JOURNAL OF IMMUNOLOGY

Hepatocytes induce Foxp3+ regulatory T cells by Notch signaling

(2014) Sven Burghardt et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Post-translational modification networks regulating FOXP3 function

(2014) Jorg van Loosdregt et al.   TRENDS IN IMMUNOLOGY

Genetic predisposition and environmental danger signals initiate chronic autoimmune hepatitis driven by CD4+T cells

(2013) Matthias Hardtke-Wolenski et al.   HEPATOLOGY

Hepatocytes Contribute to Immune Regulation in the Liver by Activation of the Notch Signaling Pathway in T Cells

(2013) S. Burghardt et al.   JOURNAL OF IMMUNOLOGY

Regulatory T cells and autoimmune hepatitis: Defective cells or a hostile environment?

(2012) Ye H. Oo et al.   JOURNAL OF HEPATOLOGY

A transcription activator-like effector toolbox for genome engineering

(2012) Neville E Sanjana et al.   Nature Protocols

Distinct Spatial and Molecular Features of Notch Pathway Assembly in Regulatory T Cells

(2012) L. R. Perumalsamy et al.   Science Signaling

Regulatory T cells and Foxp3

(2011) Alexander Y. Rudensky   IMMUNOLOGICAL REVIEWS

Apolipoprotein A-II Suppressed Concanavalin A-Induced Hepatitis via the Inhibition of CD4 T Cell Function

(2011) J. Yamashita et al.   JOURNAL OF IMMUNOLOGY

Advances in the Diagnosis, Pathogenesis, and Management of Autoimmune Hepatitis

(2010) Albert J. Czaja et al.   GASTROENTEROLOGY

Autoimmune hepatitis: new paradigms in the pathogenesis, diagnosis, and management

(2010) Ye H. Oo et al.   Hepatology International

Distinct Roles for CCR4 and CXCR3 in the Recruitment and Positioning of Regulatory T Cells in the Inflamed Human Liver

(2010) Y. H. Oo et al.   JOURNAL OF IMMUNOLOGY

Regulatory T cells exert checks and balances on self tolerance and autoimmunity

(2009) Kajsa Wing et al.   NATURE IMMUNOLOGY

Ectopic expression of neural autoantigen in mouse liver suppresses experimental autoimmune neuroinflammation by inducing antigen-specific Tregs

(2008) Stefan Lüth et al.   JOURNAL OF CLINICAL INVESTIGATION

Notch signaling regulates the FOXP3 promoter through RBP-J- and Hes1-dependent mechanisms

(2008) Hai-Feng Ou-Yang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Regulatory T Cells: Mechanisms of Differentiation and Function

(2007) Steven Z. Josefowicz et al.   Annual Review of Immunology