Protein Inhibitor of Activated STAT (PIAS) Negatively Regulates the JAK/STAT Pathway by Inhibiting STAT Phosphorylation and Translocation

Expression of the JAK/STAT signaling pathway in the ligamentum flavum of patients with lumbar spinal canal stenosis

(2017) Hitoshi Yamahata et al.   JOURNAL OF ORTHOPAEDIC SCIENCE

Binding of a C-type lectin’s coiled-coil domain to the Domeless receptor directly activates the JAK/STAT pathway in the shrimp immune response to bacterial infection

(2017) Jie-Jie Sun et al.   PLoS Pathogens

Targeted next generation sequencing of breast implant-associated anaplastic large cell lymphoma reveals mutations in JAK/STAT signalling pathway genes, TP53 and DNMT3A

(2016) Arianna Di Napoli et al.   BRITISH JOURNAL OF HAEMATOLOGY

Suppressor of cytokine signaling 2 (SOCS2) negatively regulates the expression of antimicrobial peptides by affecting the Stat transcriptional activity in shrimp Marsupenaeus japonicus

(2016) Jie-Jie Sun et al.   FISH & SHELLFISH IMMUNOLOGY

Mutations in the JAK/STAT and RAS signaling pathways are common in intestinal T-cell lymphomas

(2016) A Nicolae et al.   LEUKEMIA

NF-κB signaling relieves negative regulation by miR-194 in hepatocellular carcinoma by suppressing the transcription factor HNF-1α

(2015) Chunyang Bao et al.   Science Signaling

NF-κB signaling relieves negative regulation by miR-194 in hepatocellular carcinoma by suppressing the transcription factor HNF-1α

(2015) Chunyang Bao et al.   Science Signaling

Role of the Cytoplasmic N-terminal Cap and Per-Arnt-Sim (PAS) Domain in Trafficking and Stabilization of Kv11.1 Channels

(2014) Ying Ke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PIAS1 negatively modulates virus triggered type I IFN signaling by blocking the DNA binding activity of IRF3

(2013) Rui Li et al.   ANTIVIRAL RESEARCH

Structure-function analysis indicates that sumoylation modulates DNA-binding activity of STAT1

(2012) Juha Grönholm et al.   BMC BIOCHEMISTRY

Neuronal Per Arnt Sim (PAS) Domain Protein 4 (NPAS4) Regulates Neurite Outgrowth and Phosphorylation of Synapsin I

(2012) Jaesuk Yun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PIASy interacts with p73α and regulates cell cycle in HEK293 cells

(2010) Chao Zhang et al.   CELLULAR IMMUNOLOGY

Sumoylation of Drosophila Transcription Factor STAT92E

(2010) Juha Grönholm et al.   Journal of Innate Immunity

PIAS proteins: pleiotropic interactors associated with SUMO

(2009) Miia M. Rytinki et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Negative regulation of constitutive NF-κB and JNK signaling by PKN1-mediated phosphorylation of TRAF1

(2008) Tomohisa Kato Jr et al.   GENES TO CELLS

Solution structures and DNA binding properties of the N-terminal SAP domains of SUMO E3 ligases fromSaccharomyces cerevisiaeandOryza sativa

(2008) Rintaro Suzuki et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS