Mepolizumab for the prevention of chronic obstructive pulmonary disease exacerbations

A pilot randomised clinical trial of mepolizumab in COPD with eosinophilic bronchitis

(2017) Angira Dasgupta et al.   EUROPEAN RESPIRATORY JOURNAL

Mepolizumab for Eosinophilic Chronic Obstructive Pulmonary Disease

(2017) Ian D. Pavord et al.   NEW ENGLAND JOURNAL OF MEDICINE

Monoclonal antibody therapy for the treatment of asthma and chronic obstructive pulmonary disease with eosinophilic inflammation

(2017) John Nixon et al.   PHARMACOLOGY & THERAPEUTICS

Interleukin-5 pathway inhibition in the treatment of eosinophilic respiratory disorders

(2016) Gilda Varricchi et al.   Current Opinion in Allergy and Clinical Immunology

Treatable traits: toward precision medicine of chronic airway diseases

(2016) Alvar Agusti et al.   EUROPEAN RESPIRATORY JOURNAL

Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma

(2016) Michael J. McGeachie et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mepolizumab: First Global Approval

(2015) Gillian M. Keating   DRUGS

Key mediators in the immunopathogenesis of allergic asthma

(2014) Sannette Hall et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Oral Glucocorticoid-Sparing Effect of Mepolizumab in Eosinophilic Asthma

(2014) Elisabeth H. Bel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mepolizumab Treatment in Patients with Severe Eosinophilic Asthma

(2014) Hector G. Ortega et al.   NEW ENGLAND JOURNAL OF MEDICINE

Benralizumab for chronic obstructive pulmonary disease and sputum eosinophilia: a randomised, double-blind, placebo-controlled, phase 2a study

(2014) Christopher E Brightling et al.   Lancet Respiratory Medicine

The Neutrophil in Chronic Obstructive Pulmonary Disease. Too Little, Too Late or Too Much, Too Soon?

(2013) Kim Hoenderdos et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial

(2012) Ian D Pavord et al.   LANCET

Pharmacokinetics and Pharmacodynamics of Mepolizumab, an Anti-Interleukin-5 Monoclonal Antibody

(2011) Deborah A. Smith et al.   CLINICAL PHARMACOKINETICS