Oleoylethanolamide prevents neuroimmune HMGB1/TLR4/NF-kB danger signaling in rat frontal cortex and depressive-like behavior induced by ethanol binge administration

A Potent Systemically Active N-Acylethanolamine Acid Amidase Inhibitor that Suppresses Inflammation and Human Macrophage Activation

(2015) Alison Ribeiro et al.   ACS Chemical Biology

TLR4 elimination prevents synaptic and myelin alterations and long-term cognitive dysfunctions in adolescent mice with intermittent ethanol treatment

(2015) Jorge Montesinos et al.   BRAIN BEHAVIOR AND IMMUNITY

Neuromelanin activates proinflammatory microglia through a caspase-8-dependent mechanism

(2015) Nikenza Viceconte et al.   Journal of Neuroinflammation

Cytokines and chemokines as biomarkers of ethanol-induced neuroinflammation and anxiety-related behavior: Role of TLR4 and TLR2

(2015) María Pascual et al.   NEUROPHARMACOLOGY

Antidepressant-like effects of oleoylethanolamide in a mouse model of chronic unpredictable mild stress

(2015) Peng Jin et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Systemic Administration of Oleoylethanolamide Protects from Neuroinflammation and Anhedonia Induced by LPS in Rats

(2015) A. Sayd et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Associations between in vivo neuroimaging and postmortem brain cytokine markers in a rodent model of Wernicke's encephalopathy

(2014) Natalie M. Zahr et al.   EXPERIMENTAL NEUROLOGY

Alcohol, Phospholipase A2-associated Neuroinflammation, and ω3 Docosahexaenoic Acid Protection

(2014) Michael A. Collins et al.   MOLECULAR NEUROBIOLOGY

Antidepressants and Changes in Concentration of Endocannabinoids and N-Acylethanolamines in Rat Brain Structures

(2014) Irena Smaga et al.   NEUROTOXICITY RESEARCH

Neuroinflammation and Neurodegeneration in Adult Rat Brain from Binge Ethanol Exposure: Abrogation by Docosahexaenoic Acid

(2014) Nuzhath Tajuddin et al.   PLoS One

Neuroimmune Activation and Myelin Changes in Adolescent Rats Exposed to High-Dose Alcohol and Associated Cognitive Dysfunction: A Review with Reference to Human Adolescent Drinking

(2013) María Pascual et al.   ALCOHOL AND ALCOHOLISM

Selenium Attenuates High Glucose-Induced ROS/TLR-4 Involved Apoptosis of Rat Cardiomyocyte

(2013) Zhong-Wei Liu et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

The systemic administration of oleoylethanolamide exerts neuroprotection of the nigrostriatal system in experimental Parkinsonism

(2013) Ramiro Gonzalez-Aparicio et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Ethanol induces TLR4/TLR2 association, triggering an inflammatory response in microglial cells

(2013) Sara Fernandez-Lizarbe et al.   JOURNAL OF NEUROCHEMISTRY

Resveratrol abrogates alcohol-induced cognitive deficits by attenuating oxidative–nitrosative stress and inflammatory cascade in the adult rat brain

(2013) Vinod Tiwari et al.   NEUROCHEMISTRY INTERNATIONAL

Oleoylethanolamide dose-dependently attenuates cocaine-induced behaviours through a PPARα receptor-independent mechanism

(2012) Ainhoa Bilbao et al.   ADDICTION BIOLOGY

Binge-like ethanol consumption increases corticosterone levels and neurodegneration whereas occupancy of type II glucocorticoid receptors with mifepristone is neuroprotective

(2012) Andrea Cippitelli et al.   ADDICTION BIOLOGY

High Mobility Group Box 1/Toll-like Receptor Danger Signaling Increases Brain Neuroimmune Activation in Alcohol Dependence

(2012) Fulton T. Crews et al.   BIOLOGICAL PSYCHIATRY

Role of intestinal permeability and inflammation in the biological and behavioral control of alcohol-dependent subjects

(2012) Sophie Leclercq et al.   BRAIN BEHAVIOR AND IMMUNITY

Toll-like receptor 4 participates in the myelin disruptions associated with chronic alcohol abuse

(2012) Silvia Alfonso-Loeches et al.   GLIA

NADPH oxidase and reactive oxygen species contribute to alcohol-induced microglial activation and neurodegeneration

(2012) Liya Qin et al.   Journal of Neuroinflammation

Adolescent binge drinking increases expression of the danger signal receptor agonist HMGB1 and toll-like receptors in the adult prefrontal cortex

(2012) R.P. Vetreno et al.   NEUROSCIENCE

Attenuation of oxidative stress, neuroinflammation, and apoptosis by curcumin prevents cognitive deficits in rats postnatally exposed to ethanol

(2012) Vinod Tiwari et al.   PSYCHOPHARMACOLOGY

Impact of TLR4 on behavioral and cognitive dysfunctions associated with alcohol-induced neuroinflammatory damage

(2011) María Pascual et al.   BRAIN BEHAVIOR AND IMMUNITY

Activation of inflammatory signaling by lipopolysaccharide produces a prolonged increase of voluntary alcohol intake in mice

(2011) Y.A. Blednov et al.   BRAIN BEHAVIOR AND IMMUNITY

High-mobility group box-1 impairs memory in mice through both toll-like receptor 4 and Receptor for Advanced Glycation End Products

(2011) Andréy Mazarati et al.   EXPERIMENTAL NEUROLOGY

Neuronal MCP-1 Mediates Microglia Recruitment and Neurodegeneration Induced by the Mild Impairment of Oxidative Metabolism

(2010) Guang Yang et al.   BRAIN PATHOLOGY

Pivotal Role of TLR4 Receptors in Alcohol-Induced Neuroinflammation and Brain Damage

(2010) S. Alfonso-Loeches et al.   JOURNAL OF NEUROSCIENCE

Mechanism of alcohol-induced oxidative stress and neuronal injury

(2008) James Haorah et al.   FREE RADICAL BIOLOGY AND MEDICINE

Increased systemic and brain cytokine production and neuroinflammation by endotoxin following ethanol treatment

(2008) Liya Qin et al.   Journal of Neuroinflammation

Endogenous Fatty Acid Ethanolamides Suppress Nicotine-Induced Activation of Mesolimbic Dopamine Neurons through Nuclear Receptors

(2008) M. Melis et al.   JOURNAL OF NEUROSCIENCE

Peroxisome Proliferator-Activated Receptors: “Key” Regulators of Neuroinflammation after Traumatic Brain Injury

(2008) Philip F. Stahel et al.   PPAR Research

Increased MCP-1 and microglia in various regions of the human alcoholic brain

(2007) Jun He et al.   EXPERIMENTAL NEUROLOGY

From inflammation to sickness and depression: when the immune system subjugates the brain

(2007) Robert Dantzer et al.   NATURE REVIEWS NEUROSCIENCE