Tumor-Specific Drug Release and Reactive Oxygen Species Generation for Cancer Chemo/Chemodynamic Combination Therapy

Hypochlorous Acid Promoted Platinum Drug Chemotherapy by Myeloperoxidase-Encapsulated Therapeutic Metal Phenolic Nanoparticles

(2018) Yunlu Dai et al.   ACS Nano

Toxic Reactive Oxygen Species Enhanced Synergistic Combination Therapy by Self-Assembled Metal-Phenolic Network Nanoparticles

(2018) Yunlu Dai et al.   ADVANCED MATERIALS

Concurrent Drug Unplugging and Permeabilization of Polyprodrug-Gated Crosslinked Vesicles for Cancer Combination Chemotherapy

(2018) Xianglong Hu et al.   ADVANCED MATERIALS

Simultaneous Fenton-like Ion Delivery and Glutathione Depletion by MnO2 -Based Nanoagent to Enhance Chemodynamic Therapy

(2018) Li-Sen Lin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Platinum(IV) complex-based two-in-one polyprodrug for a combinatorial chemo-photodynamic therapy

(2018) Dongbo Guo et al.   BIOMATERIALS

Overcoming obstacles in the tumor microenvironment: Recent advancements in nanoparticle delivery for cancer theranostics

(2018) Marta Overchuk et al.   BIOMATERIALS

Two-dimensional tellurium nanosheets for photoacoustic imaging-guided photodynamic therapy

(2018) Yan Lin et al.   CHEMICAL COMMUNICATIONS

Positively Charged Polyprodrug Amphiphiles with Enhanced Drug Loading and Reactive Oxygen Species-Responsive Release Ability for Traceable Synergistic Therapy

(2018) Yan Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stimuli-Responsive Nanomedicines for Overcoming Cancer Multidrug Resistance

(2018) Lei Zhou et al.   Theranostics

Oxygen-generating Hybrid Polymeric Nanoparticles with Encapsulated Doxorubicin and Chlorin e6 for Trimodal Imaging-Guided Combined Chemo-Photodynamic Therapy

(2018) DanRong Hu et al.   Theranostics

Novel functionalized nanoparticles for tumor-targeting co-delivery of doxorubicin and siRNA to enhance cancer therapy

(2017) Yu Xia et al.   International Journal of Nanomedicine

Synergistic antitumor activity of a self-assembling camptothecin and capecitabine hybrid prodrug for improved efficacy

(2017) Wang Ma et al.   JOURNAL OF CONTROLLED RELEASE

Polymer Prodrug-Based Nanoreactors Activated by Tumor Acidity for Orchestrated Oxidation/Chemotherapy

(2017) Junjie Li et al.   NANO LETTERS

Enhanced Cisplatin Chemotherapy by Iron Oxide Nanocarrier-Mediated Generation of Highly Toxic Reactive Oxygen Species

(2017) Ping’an Ma et al.   NANO LETTERS

Black Phosphorus Quantum Dots with Renal Clearance Property for Efficient Photodynamic Therapy

(2017) Tao Guo et al.   Small

Bioreducible amphiphilic block copolymers based on PCL and glycopolypeptide as multifunctional theranostic nanocarriers for drug delivery and MR imaging

(2017) Hui-Kang Yang et al.   RSC Advances

pH-Responsive Aerobic Nanoparticles for Effective Photodynamic Therapy

(2017) Lingyue Shen et al.   Theranostics

Aminoglucose-functionalized, redox-responsive polymer nanomicelles for overcoming chemoresistance in lung cancer cells

(2017) Yi Zhou et al.   JOURNAL OF NANOBIOTECHNOLOGY

Ultrasound-Induced Reactive Oxygen Species Mediated Therapy and Imaging Using a Fenton Reaction Activable Polymersome

(2016) Wei-Peng Li et al.   ACS Nano

Intracellularly Acid-Switchable Multifunctional Micelles for Combinational Photo/Chemotherapy of the Drug-Resistant Tumor

(2016) Tingting Wang et al.   ACS Nano

Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy

(2016) Zijian Zhou et al.   CHEMICAL SOCIETY REVIEWS

Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems

(2016) Mahdi Karimi et al.   CHEMICAL SOCIETY REVIEWS

Self-sufficing H2O2-responsive nanocarriers through tumor-specific H2O2 production for synergistic oxidation-chemotherapy

(2016) Junjie Li et al.   JOURNAL OF CONTROLLED RELEASE

Supramolecular Crafting of Self-Assembling Camptothecin Prodrugs with Enhanced Efficacy against Primary Cancer Cells

(2016) Hao Su et al.   Theranostics

pH- and NIR light responsive nanocarriers for combination treatment of chemotherapy and photodynamic therapy

(2016) Sheng Wang et al.   Biomaterials Science

Smart pH-responsive upconversion nanoparticles for enhanced tumor cellular internalization and near-infrared light-triggered photodynamic therapy

(2015) Sheng Wang et al.   CHEMICAL COMMUNICATIONS

Nanoparticles in Photodynamic Therapy

(2015) Sasidharan Swarnalatha Lucky et al.   CHEMICAL REVIEWS

Esterase-activatable β-lapachone prodrug micelles for NQO1-targeted lung cancer therapy

(2015) Xinpeng Ma et al.   JOURNAL OF CONTROLLED RELEASE

Nanotechnology-enabled delivery of NQO1 bioactivatable drugs

(2015) Xinpeng Ma et al.   JOURNAL OF DRUG TARGETING

Functional Nanomaterials for Phototherapies of Cancer

(2014) Liang Cheng et al.   CHEMICAL REVIEWS

Cell-Penetrating Hyperbranched Polyprodrug Amphiphiles for Synergistic Reductive Milieu-Triggered Drug Release and Enhanced Magnetic Resonance Signals

(2014) Xianglong Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Prodrug Strategy to Achieve Lyophilizable, High Drug Loading Micelle Formulations Through Diester Derivatives of β-Lapachone

(2014) Xinpeng Ma et al.   Advanced Healthcare Materials

Smart pH-Sensitive and Temporal-Controlled Polymeric Micelles for Effective Combination Therapy of Doxorubicin and Disulfiram

(2013) Xiaopin Duan et al.   ACS Nano

Functional block copolymer assemblies responsive to tumor and intracellular microenvironments for site-specific drug delivery and enhanced imaging performance

(2013) Zhishen Ge et al.   CHEMICAL SOCIETY REVIEWS

Polyprodrug Amphiphiles: Hierarchical Assemblies for Shape-Regulated Cellular Internalization, Trafficking, and Drug Delivery

(2013) Xianglong Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stimuli-responsive nanocarriers for drug delivery

(2013) Simona Mura et al.   NATURE MATERIALS

A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals

(2013) Yiguang Wang et al.   NATURE MATERIALS

Superparamagnetic Iron Oxide Nanoparticles: Amplifying ROS Stress to Improve Anticancer Drug Efficacy

(2013) Gang Huang et al.   Theranostics

DNA Self-Assembly of Targeted Near-Infrared-Responsive Gold Nanoparticles for Cancer Thermo-Chemotherapy

(2012) Zeyu Xiao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multifunctional Nanoparticles: Cost Versus Benefit of Adding Targeting and Imaging Capabilities

(2012) Z. Cheng et al.   SCIENCE

pH-Tunable Calcium Phosphate Covered Mesoporous Silica Nanocontainers for Intracellular Controlled Release of Guest Drugs

(2011) Hwa Pyeong Rim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recyclable Antibacterial Magnetic Nanoparticles Grafted with Quaternized Poly(2-(dimethylamino)ethyl methacrylate) Brushes

(2011) Hongchen Dong et al.   BIOMACROMOLECULES

Norbornene Derived Doxorubicin Copolymers as Drug Carriers with pH Responsive Hydrazone Linker

(2011) Vijayakameswara Rao N et al.   BIOMACROMOLECULES

Chemistry and biology of reactive oxygen species in signaling or stress responses

(2011) Bryan C Dickinson et al.   Nature Chemical Biology

 -Lapachone Micellar Nanotherapeutics for Non-Small Cell Lung Cancer Therapy

(2010) E. Blanco et al.   CANCER RESEARCH

Multicolor Core/Shell-Structured Upconversion Fluorescent Nanoparticles

(2008) Zhengquan Li et al.   ADVANCED MATERIALS

Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice

(2008) Q. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA