Membrane Destabilization Induced by Lipid Species Increases Activity of Phosphorothioate-Antisense Oligonucleotides

Published 2018 View Full Article

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Title
Membrane Destabilization Induced by Lipid Species Increases Activity of Phosphorothioate-Antisense Oligonucleotides
Authors
Keywords
antisense oligonucleotides, free fatty acids, ceramide, cholesterol, intracellular trafficking, endosomal leakiness
Journal
Molecular Therapy-Nucleic Acids
Volume 13, Issue -, Pages 686-698
Publisher
Elsevier BV
Online
2018-10-24
DOI
10.1016/j.omtn.2018.10.011

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