N6-methyladenosine (m6A): Revisiting the Old with Focus on New, an Arabidopsis thaliana Centered Review

Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d

(2018) Philip Knuckles et al.   GENES & DEVELOPMENT

Zc3h13 Regulates Nuclear RNA m 6 A Methylation and Mouse Embryonic Stem Cell Self-Renewal

(2018) Jing Wen et al.   MOLECULAR CELL

An m6A-YTH Module Controls Developmental Timing and Morphogenesis in Arabidopsis

(2018) Laura Arribas-Hernández et al.   PLANT CELL

The m6A Reader ECT2 Controls Trichome Morphology by Affecting mRNA Stability in Arabidopsis

(2018) Lian-Huan Wei et al.   PLANT CELL

The YTH Domain Protein ECT2 Is an m6A Reader Required for Normal Trichome Branching in Arabidopsis

(2018) Jérémy Scutenaire et al.   PLANT CELL

Xio is a component of theDrosophilasex determination pathway and RNAN6-methyladenosine methyltransferase complex

(2018) Jian Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

N6-methyl-adenosine level in Nicotiana tabacum is associated with tobacco mosaic virus

(2018) Zhurui Li et al.   Virology Journal

VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

(2018) Yanan Yue et al.   Cell Discovery

N6-Methyladenosine Inhibits Local Ribonucleolytic Cleavage to Stabilize mRNAs in Arabidopsis

(2018) Stephen J. Anderson et al.   Cell Reports

N6-Methyladenosine RNA Modification Regulates Shoot Stem Cell Fate in Arabidopsis

(2017) Lisha Shen et al.   MECHANISMS OF DEVELOPMENT

Identification of factors required for m6 A mRNA methylation in Arabidopsis reveals a role for the conserved E3 ubiquitin ligase HAKAI

(2017) Kamil Růžička et al.   NEW PHYTOLOGIST

N 6-methyladenosine alters RNA structure to regulate binding of a low-complexity protein

(2017) Nian Liu et al.   NUCLEIC ACIDS RESEARCH

ALKBH10B Is an RNAN6-Methyladenosine Demethylase Affecting Arabidopsis Floral Transition

(2017) Hong-Chao Duan et al.   PLANT CELL

Arabidopsism6A demethylase activity modulates viral infection of a plant virus and the m6A abundance in its genomic RNAs

(2017) Mireya Martínez-Pérez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The m6A pathway facilitates sex determination in Drosophila

(2017) Lijuan Kan et al.   Nature Communications

N 6 -Methyladenosine Modification in a Long Noncoding RNA Hairpin Predisposes Its Conformation to Protein Binding

(2016) Katherine I. Zhou et al.   JOURNAL OF MOLECULAR BIOLOGY

m6A potentiates Sxl alternative pre-mRNA splicing for robust Drosophila sex determination

(2016) Irmgard U. Haussmann et al.   NATURE

Post-transcriptional gene regulation by mRNA modifications

(2016) Boxuan Simen Zhao et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

YTHDF2 destabilizes m6A-containing RNA through direct recruitment of the CCR4–NOT deadenylase complex

(2016) Hao Du et al.   Nature Communications

Recent advances in dynamic m6A RNA modification

(2016) Guangchao Cao et al.   Open Biology

HNRNPA2B1 Is a Mediator of m6A-Dependent Nuclear RNA Processing Events

(2015) Claudio R. Alarcón et al.   CELL

Structure and Thermodynamics of N6-Methyladenosine in RNA: A Spring-Loaded Base Modification

(2015) Caroline Roost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N6-methyladenosine marks primary microRNAs for processing

(2015) Claudio R. Alarcón et al.   NATURE

N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions

(2015) Nian Liu et al.   NATURE

Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome

(2015) Bastian Linder et al.   NATURE METHODS

Widespread occurrence ofN6-methyladenosine in bacterial mRNA

(2015) Xin Deng et al.   NUCLEIC ACIDS RESEARCH

m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation

(2015) Shay Geula et al.   SCIENCE

Arabidopsis microRNA expression regulation in a wide range of abiotic stress responses

(2015) Maria Barciszewska-Pacak et al.   Frontiers in Plant Science

Transcriptome-wide N6-methyladenosine profiling of rice callus and leaf reveals the presence of tissue-specific competitors involved in selective mRNA modification

(2014) Yuli Li et al.   RNA Biology

Unique features of the m6A methylome in Arabidopsis thaliana

(2014) Guan-Zheng Luo et al.   Nature Communications

Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites

(2014) Schraga Schwartz et al.   Cell Reports

Identification of Wilms' Tumor 1-associating Protein Complex and Its Role in Alternative Splicing and the Cell Cycle

(2013) Keiko Horiuchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

(2013) Jianzhao Liu et al.   Nature Chemical Biology

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

(2012) Kate D. Meyer et al.   CELL

Role of microRNAs and other sRNAs of plants in their changing environments

(2012) Katarzyna Kruszka et al.   JOURNAL OF PLANT PHYSIOLOGY

ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

(2012) Guanqun Zheng et al.   MOLECULAR CELL

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

(2012) Dan Dominissini et al.   NATURE

Functions of microRNAs in plant stress responses

(2012) Ramanjulu Sunkar et al.   TRENDS IN PLANT SCIENCE

Adenosine Methylation in Arabidopsis mRNA is Associated with the 3′ End and Reduced Levels Cause Developmental Defects

(2012) Zsuzsanna Bodi et al.   Frontiers in Plant Science

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

The YTH Domain Is a Novel RNA Binding Domain

(2010) Zhaiyi Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MTA Is an Arabidopsis Messenger RNA Adenosine Methylase and Interacts with a Homolog of a Sex-Specific Splicing Factor

(2008) S. Zhong et al.   PLANT CELL