Proarrhythmic Remodeling of Calcium Homeostasis in Cardiac Disease; Implications for Diabetes and Obesity
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Proarrhythmic Remodeling of Calcium Homeostasis in Cardiac Disease; Implications for Diabetes and Obesity
Authors
Keywords
-
Journal
Frontiers in Physiology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-10-30
DOI
10.3389/fphys.2018.01517
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Hyperactive ryanodine receptors in human heart failure and ischaemic cardiomyopathy reside outside of couplons
- (2018) Eef Dries et al. CARDIOVASCULAR RESEARCH
- Lnc’ing Ca 2+ , SERCA and cardiac disease
- (2018) Tim Vervliet et al. CELL CALCIUM
- Heart Disease and Stroke Statistics—2018 Update: A Report From the American Heart Association
- (2018) Emelia J. Benjamin et al. CIRCULATION
- Diabetic Cardiomyopathy
- (2018) Guanghong Jia et al. CIRCULATION RESEARCH
- Hypertension with diabetes mellitus: physiology and pathology
- (2018) Mitsuru Ohishi HYPERTENSION RESEARCH
- High-Fat-Diet-Induced Obesity Produces Spontaneous Ventricular Arrhythmias and Increases the Activity of Ryanodine Receptors in Mice
- (2018) Gina Sánchez et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The cardiac ryanodine receptor, but not sarcoplasmic reticulum Ca2+-ATPase, is a major determinant of Ca2+ alternans in intact mouse hearts
- (2018) Bo Sun et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Stabilization of Ca 2+ signaling in cardiac muscle by stimulation of SERCA
- (2018) Miguel Fernandez-Tenorio et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Reactive oxygen species mediated oxidative stress links diabetes and atrial fibrillation
- (2018) Xue Liang et al. Molecular Medicine Reports
- Metabolic remodelling in heart failure
- (2018) Edoardo Bertero et al. Nature Reviews Cardiology
- Gene Transfer of Engineered Calmodulin Alleviates Ventricular Arrhythmias in a Calsequestrin‐Associated Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia
- (2018) Bin Liu et al. Journal of the American Heart Association
- Xanthine Oxidase Inhibitor Allopurinol Prevents Oxidative Stress‐Mediated Atrial Remodeling in Alloxan‐Induced Diabetes Mellitus Rabbits
- (2018) Yajuan Yang et al. Journal of the American Heart Association
- NCX-Mediated Subcellular Ca2+ Dynamics Underlying Early Afterdepolarizations in LQT2 Cardiomyocytes
- (2018) Mingwang Zhong et al. BIOPHYSICAL JOURNAL
- Diabetes-related cardiomyopathy: The sweet story of glucose overload from epidemiology to cellular pathways
- (2018) M. Joubert et al. DIABETES & METABOLISM
- A pore-localizing CACNA1C-E1115K missense mutation, identified in a patient with idiopathic QT prolongation, bradycardia, and autism spectrum disorder, converts the L-type calcium channel into a hybrid nonselective monovalent cation channel
- (2018) Dan Ye et al. HEART RHYTHM
- Arrhythmogenic gene remodelling in elderly patients with type 2 diabetes with aortic stenosis and normal left ventricular ejection fraction
- (2017) R. Ashrafi et al. EXPERIMENTAL PHYSIOLOGY
- Reactive oxygen species signalling in the diabetic heart: emerging prospect for therapeutic targeting
- (2017) Adam J Wilson et al. HEART
- Hyperglycemia-induced cardiac contractile dysfunction in the diabetic heart
- (2017) Raphael M. Singh et al. HEART FAILURE REVIEWS
- Long-Standing Problem of β-Blocker–Elicited Hypoglycemia in Diabetes Mellitus
- (2017) Edoardo Casiglia et al. HYPERTENSION
- Risk of Cardiovascular Events in Patients With Diabetes Mellitus on β-BlockersNovelty and Significance
- (2017) Tetsuro Tsujimoto et al. HYPERTENSION
- Treatment of catecholaminergic polymorphic ventricular tachycardia in mice using novel RyR2-modifying drugs
- (2017) Na Li et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Extensive Ca2+leak through K4750Q cardiac ryanodine receptors caused by cytosolic and luminal Ca2+hypersensitivity
- (2017) Akira Uehara et al. JOURNAL OF GENERAL PHYSIOLOGY
- The structural basis of ryanodine receptor ion channel function
- (2017) Gerhard Meissner JOURNAL OF GENERAL PHYSIOLOGY
- The effect of PKA-mediated phosphorylation of ryanodine receptor on SR Ca2+ leak in ventricular myocytes
- (2017) Elisa Bovo et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Sarcoplasmic reticulum–mitochondria communication in cardiovascular pathophysiology
- (2017) Camila Lopez-Crisosto et al. Nature Reviews Cardiology
- Roles of impaired intracellular calcium cycling in arrhythmogenicity of diabetic mouse model
- (2017) Chung-Chuan Chou et al. PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
- CaMKII: The molecular villain that aggravates cardiovascular disease
- (2017) Peiying Zhang Experimental and Therapeutic Medicine
- Alogliptin, a Dipeptidyl Peptidase‐4 Inhibitor, Alleviates Atrial Remodeling and Improves Mitochondrial Function and Biogenesis in Diabetic Rabbits
- (2017) Xiaowei Zhang et al. Journal of the American Heart Association
- The Effects of SEA0400 on Ca2+ Transient Amplitude and Proarrhythmia Depend on the Na+/Ca2+ Exchanger Expression Level in Murine Models
- (2017) Nils Bögeholz et al. Frontiers in Pharmacology
- Animal models for diabetes: Understanding the pathogenesis and finding new treatments
- (2016) Aileen King et al. BIOCHEMICAL PHARMACOLOGY
- Electrophysiological basis of metabolic-syndrome-induced cardiac dysfunction
- (2016) Esma N. Okatan et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- Mitochondrial oxidative stress during cardiac lipid overload causes intracellular calcium leak and arrhythmia
- (2016) Leroy C. Joseph et al. HEART RHYTHM
- Ryanodine receptor phosphorylation by CaMKII promotes spontaneous Ca2+ release events in a rodent model of early stage diabetes: The arrhythmogenic substrate
- (2016) Leandro Sommese et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- SERCA2a upregulation ameliorates cellular alternans induced by metabolic inhibition
- (2016) Victoria Stary et al. JOURNAL OF APPLIED PHYSIOLOGY
- CaMKII-dependent phosphorylation of RyR2 promotes targetable pathological RyR2 conformational shift
- (2016) Hitoshi Uchinoumi et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Regulation of sarcoplasmic reticulum Ca2+ release by serine-threonine phosphatases in the heart
- (2016) Dmitry Terentyev et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Calcium upregulation by percutaneous administration of gene therapy in patients with cardiac disease (CUPID 2): a randomised, multinational, double-blind, placebo-controlled, phase 2b trial
- (2016) Barry Greenberg et al. LANCET
- Molecular and Electrophysiological Mechanisms Underlying Cardiac Arrhythmogenesis in Diabetes Mellitus
- (2016) Gary Tse et al. Journal of Diabetes Research
- High-Throughput Screens to Discover Small-Molecule Modulators of Ryanodine Receptor Calcium Release Channels
- (2016) Robyn T. Rebbeck et al. SLAS Discovery
- The Role of Reactive Oxygen Species in β-Adrenergic Signaling in Cardiomyocytes from Mice with the Metabolic Syndrome
- (2016) Monica Llano-Diez et al. PLoS One
- Phospholamban Ablation Using CRISPR/Cas9 System Improves Mortality in a Murine Heart Failure Model
- (2016) Manami Kaneko et al. PLoS One
- Non- -blocking R-carvedilol enantiomer suppresses Ca2+ waves and stress-induced ventricular tachyarrhythmia without lowering heart rate or blood pressure
- (2015) J. Zhang et al. BIOCHEMICAL JOURNAL
- Sarcoplasmic reticulum Ca2+ ATPase pump is a major regulator of glucose transport in the healthy and diabetic heart
- (2015) Amanda P. Waller et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis
- (2015) Lene Nygaard Axelsen et al. Cardiovascular Diabetology
- Altered Myocardial Calcium Cycling and Energetics in Heart Failure—A Rational Approach for Disease Treatment
- (2015) Przemek A. Gorski et al. Cell Metabolism
- Suppression of Early and Late Afterdepolarizations by Heterozygous Knockout of the Na+/Ca2+Exchanger in a Murine Model
- (2015) Nils Bögeholz et al. Circulation-Arrhythmia and Electrophysiology
- Calcium/calmodulin-dependent protein kinase II (CaMKII) inhibition ameliorates arrhythmias elicited by junctin ablation under stress conditions
- (2015) Christos Tzimas et al. HEART RHYTHM
- Attenuation of Ca2+ homeostasis, oxidative stress, and mitochondrial dysfunctions in diabetic rat heart: insulin therapy or aerobic exercise?
- (2015) Márcia F. da Silva et al. JOURNAL OF APPLIED PHYSIOLOGY
- Oxidant stress promotes disease by activating CaMKII
- (2015) Mark E. Anderson JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Arrhythmogenesis in a catecholaminergic polymorphic ventricular tachycardia mutation that depresses ryanodine receptor function
- (2015) Yan-Ting Zhao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Selective Na+/Ca2+exchanger inhibition prevents Ca2+overload-induced triggered arrhythmias
- (2014) Norbert Nagy et al. BRITISH JOURNAL OF PHARMACOLOGY
- Progressive decay of Ca2+ homeostasis in the development of diabetic cardiomyopathy
- (2014) Shu-Mei Zhao et al. Cardiovascular Diabetology
- Regulation of SERCA pumps expression in diabetes
- (2014) Angel Zarain-Herzberg et al. CELL CALCIUM
- Cardiac alternans and intracellular calcium cycling
- (2014) Joshua N Edwards et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Effects of a sucrose-enriched diet on the pattern of gene expression, contraction and Ca2+transport in Goto-Kakizaki type 2 diabetic rat heart
- (2014) E. M. Gaber et al. EXPERIMENTAL PHYSIOLOGY
- Sudden cardiac death and diabetes mellitus
- (2014) I. Vasiliadis et al. JOURNAL OF DIABETES AND ITS COMPLICATIONS
- CaMKII oxidative activation and the pathogenesis of cardiac disease
- (2014) Elizabeth D. Luczak et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Enhancement of Cellular Antioxidant-Defence Preserves Diastolic Dysfunction via Regulation of Both Diastolic Zn2+and Ca2+and Prevention of RyR2-Leak in Hyperglycemic Cardiomyocytes
- (2014) Erkan Tuncay et al. Oxidative Medicine and Cellular Longevity
- Ca handling during excitation–contraction coupling in heart failure
- (2014) Aleksey V. Zima et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Inhibition of CaMKII Does Not Attenuate Cardiac Hypertrophy in Mice with Dysfunctional Ryanodine Receptor
- (2014) Asima Chakraborty et al. PLoS One
- Glutathione oxidation unmasks proarrhythmic vulnerability of chronically hyperglycemic guinea pigs
- (2013) Chaoqin Xie et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- ORM-10103, a novel specific inhibitor of the Na+/Ca2+exchanger, decreases early and delayed afterdepolarizations in the canine heart
- (2013) N Jost et al. BRITISH JOURNAL OF PHARMACOLOGY
- Calmodulin Mutations Associated With Recurrent Cardiac Arrest in Infants
- (2013) Lia Crotti et al. CIRCULATION
- Production of Reactive Oxygen Species in the Diabetic Heart
- (2013) Yasushi Teshima et al. CIRCULATION JOURNAL
- Phospholamban Knockout Breaks Arrhythmogenic Ca 2+ Waves and Suppresses Catecholaminergic Polymorphic Ventricular Tachycardia in Mice
- (2013) Yunlong Bai et al. CIRCULATION RESEARCH
- Long-Term Effects of AAV1/SERCA2a Gene Transfer in Patients With Severe Heart Failure
- (2013) Krisztina Zsebo et al. CIRCULATION RESEARCH
- Combined Na + /Ca 2+ Exchanger and L-Type Calcium Channel Block as a Potential Strategy to Suppress Arrhythmias and Maintain Ventricular Function
- (2013) Vincent J.A. Bourgonje et al. Circulation-Arrhythmia and Electrophysiology
- Exome Sequencing and Systems Biology Converge to Identify Novel Mutations in the L-Type Calcium Channel, CACNA1C , Linked to Autosomal Dominant Long QT Syndrome
- (2013) Nicole J. Boczek et al. Circulation-Cardiovascular Genetics
- Regulation of the Na+/Ca2+Exchanger by Pyridine Nucleotide Redox Potential in Ventricular Myocytes
- (2013) Ting Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Interactions between sarco-endoplasmic reticulum and mitochondria in cardiac and skeletal muscle - pivotal roles in Ca2+ and reactive oxygen species signaling
- (2013) V. Eisner et al. JOURNAL OF CELL SCIENCE
- 2013 ESH/ESC Guidelines for the management of arterial hypertension
- (2013) Giuseppe Mancia et al. JOURNAL OF HYPERTENSION
- Mitochondrial targets for arrhythmia suppression: is there a role for pharmacological intervention?
- (2013) Fadi G. Akar JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
- Pernicious attrition and inter-RyR2 CICR current control in cardiac muscle
- (2013) Dirk Gillespie et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Na/Ca exchange and contraction of the heart
- (2013) Michela Ottolia et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Na+ transport in the normal and failing heart — Remember the balance
- (2013) Sanda Despa et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Redox modification of ryanodine receptors by mitochondria-derived reactive oxygen species contributes to aberrant Ca2+handling in ageing rabbit hearts
- (2013) Leroy L. Cooper et al. JOURNAL OF PHYSIOLOGY-LONDON
- A Mutation in CALM1 Encoding Calmodulin in Familial Idiopathic Ventricular Fibrillation in Childhood and Adolescence
- (2013) Roos F. Marsman et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Effects of exercise training on excitation–contraction coupling and related mRNA expression in hearts of Goto-Kakizaki type 2 diabetic rats
- (2013) K. A. Salem et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation
- (2013) Jeffrey R. Erickson et al. NATURE
- Dependency of Calcium Alternans on Ryanodine Receptor Refractoriness
- (2013) Enric Alvarez-Lacalle et al. PLoS One
- Decreased RyR2 refractoriness determines myocardial synchronization of aberrant Ca2+ release in a genetic model of arrhythmia
- (2013) L. Brunello et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutations in Calmodulin Cause Ventricular Tachycardia and Sudden Cardiac Death
- (2012) Mette Nyegaard et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Na+/Ca2+ exchanger-1 protects against systolic failure in the Akitains2 model of diabetic cardiomyopathy via a CXCR4/NF-κB pathway
- (2012) Thomas J. LaRocca et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Calcium alternans in a couplon network model of ventricular myocytes: role of sarcoplasmic reticulum load
- (2012) Michael Nivala et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Refractoriness of sarcoplasmic reticulum Ca2+ release determines Ca2+ alternans in atrial myocytes
- (2012) Vyacheslav M. Shkryl et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Combined insulin treatment and intense exercise training improved basal cardiac function and Ca2+-cycling proteins expression in type 1 diabetic rats
- (2012) Solène Le Douairon Lahaye et al. Applied Physiology Nutrition and Metabolism
- Proarrhythmia in a non-failing murine model of cardiac-specific Na+/Ca2+ exchanger overexpression: whole heart and cellular mechanisms
- (2012) Christian Pott et al. BASIC RESEARCH IN CARDIOLOGY
- Posttranslational modifications of cardiac ryanodine receptors: Ca2+ signaling and EC-coupling
- (2012) Ernst Niggli et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- The use of animal models in diabetes research
- (2012) Aileen JF King BRITISH JOURNAL OF PHARMACOLOGY
- Increased myocardial SERCA expression in early type 2 diabetes mellitus is insulin dependent: In vivo and in vitro data
- (2012) Sabine Fredersdorf et al. Cardiovascular Diabetology
- Intracellular Levels of Na+ and TTX-sensitive Na+ Channel Current in Diabetic Rat Ventricular Cardiomyocytes
- (2012) Ayca Bilginoglu et al. Cardiovascular Toxicology
- Role of Substrate and Triggers in the Genesis of Cardiac Alternans, From the Myocyte to the Whole Heart
- (2012) Faisal M. Merchant et al. CIRCULATION
- Shortened Ca 2+ Signaling Refractoriness Underlies Cellular Arrhythmogenesis in a Postinfarction Model of Sudden Cardiac Death
- (2012) Andriy E. Belevych et al. CIRCULATION RESEARCH
- Role of RyR2 Phosphorylation at S2814 During Heart Failure Progression
- (2012) Jonathan L. Respress et al. CIRCULATION RESEARCH
- Modulation of Cardiac Contractility by the Phopholamban/SERCA2a Regulatome
- (2012) Evangelia G. Kranias et al. CIRCULATION RESEARCH
- Heterogeneity of Ryanodine Receptor Dysfunction in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia
- (2012) Randall Loaiza et al. CIRCULATION RESEARCH
- Inhibition of CaMKII phosphorylation of RyR2 prevents inducible ventricular arrhythmias in mice with Duchenne muscular dystrophy
- (2012) Sameer Ather et al. HEART RHYTHM
- Absence of triadin, a protein of the calcium release complex, is responsible for cardiac arrhythmia with sudden death in human
- (2012) Nathalie Roux-Buisson et al. HUMAN MOLECULAR GENETICS
- CaV1.2 signaling complexes in the heart
- (2012) Robert D. Harvey et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Termination of calcium-induced calcium release by induction decay: An emergent property of stochastic channel gating and molecular scale architecture
- (2012) D.R. Laver et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- SR and mitochondria: Calcium cross-talk between kissing cousins
- (2012) Gerald W. Dorn et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Calcium flux balance in the heart
- (2012) David Eisner et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Inherited calcium channelopathies in the pathophysiology of arrhythmias
- (2012) Luigi Venetucci et al. Nature Reviews Cardiology
- Calsequestrin Mutations and Catecholaminergic Polymorphic Ventricular Tachycardia
- (2012) Michela Faggioni et al. PEDIATRIC CARDIOLOGY
- Cardiac Sarcoplasmic Reticulum Calcium Leak: Basis and Roles in Cardiac Dysfunction
- (2011) Donald M. Bers Annual Review of Physiology
- The relationship between arrhythmogenesis and impaired contractility in heart failure: role of altered ryanodine receptor function
- (2011) Andriy E. Belevych et al. CARDIOVASCULAR RESEARCH
- Gain of function of cardiac ryanodine receptor in a rat model of type 1 diabetes
- (2011) Chengju Tian et al. CARDIOVASCULAR RESEARCH
- Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID)
- (2011) Mariell Jessup et al. CIRCULATION
- Inherited Dysfunction of Sarcoplasmic Reticulum Ca 2+ Handling and Arrhythmogenesis
- (2011) Silvia G. Priori et al. CIRCULATION RESEARCH
- SERCA2a Gene Transfer Decreases Sarcoplasmic Reticulum Calcium Leak and Reduces Ventricular Arrhythmias in a Model of Chronic Heart Failure
- (2011) Alexander R. Lyon et al. Circulation-Arrhythmia and Electrophysiology
- Triple Threat: The Na+/Ca2+ Exchanger in the Pathophysiology of Cardiac Arrhythmia, Ischemia and Heart Failure
- (2011) Christian Pott et al. CURRENT DRUG TARGETS
- Carbonylation Contributes to SERCA2a Activity Loss and Diastolic Dysfunction in a Rat Model of Type 1 Diabetes
- (2011) Chun Hong Shao et al. DIABETES
- BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes
- (2011) Ting-Ting Hong et al. HEART RHYTHM
- Restoration of Defective L-type Ca2+ Current in Cardiac Myocytes of Type 2 Diabetic db/db Mice by Akt and PKC-ι
- (2011) Zhongju Lu et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- How to stop the fire? Control of Ca2+-induced Ca2+release in cardiac muscle
- (2011) Yukiko Kunitomo et al. JOURNAL OF PHYSIOLOGY-LONDON
- Carvedilol and its new analogs suppress arrhythmogenic store overload–induced Ca2+ release
- (2011) Qiang Zhou et al. NATURE MEDICINE
- Alternative strategies in arrhythmia therapy: Evaluation of Na/Ca exchange as an anti-arrhythmic target
- (2011) Gudrun Antoons et al. PHARMACOLOGY & THERAPEUTICS
- Changes in the Organization of Excitation-Contraction Coupling Structures in Failing Human Heart
- (2011) David J. Crossman et al. PLoS One
- MicroRNA-1 and -133 Increase Arrhythmogenesis in Heart Failure by Dissociating Phosphatase Activity from RyR2 Complex
- (2011) Andriy E. Belevych et al. PLoS One
- Calcium Signaling in Cardiac Myocytes
- (2011) C. J. Fearnley et al. Cold Spring Harbor Perspectives in Biology
- Sodium-Calcium Exchange Is Essential for Effective Triggering of Calcium Release in Mouse Heart
- (2010) Patricia Neco et al. BIOPHYSICAL JOURNAL
- The SR-mitochondria interaction: a new player in cardiac pathophysiology
- (2010) M. Ruiz-Meana et al. CARDIOVASCULAR RESEARCH
- Dantrolene, a Therapeutic Agent for Malignant Hyperthermia, Inhibits Catecholaminergic Polymorphic Ventricular Tachycardia in a RyR2R2474S/+ Knock-In Mouse Model
- (2010) Shigeki Kobayashi et al. CIRCULATION JOURNAL
- Kinetics of FKBP12.6 Binding to Ryanodine Receptors in Permeabilized Cardiac Myocytes and Effects on Ca Sparks
- (2010) Tao Guo et al. CIRCULATION RESEARCH
- T-Tubule Remodeling During Transition From Hypertrophy to Heart Failure
- (2010) Sheng Wei et al. CIRCULATION RESEARCH
- Targeting Sarcoplasmic Reticulum Ca 2+ Uptake to Improve Heart Failure
- (2010) Karin R. Sipido et al. CIRCULATION RESEARCH
- Inhibition of Elevated Ca 2+ /Calmodulin-Dependent Protein Kinase II Improves Contractility in Human Failing Myocardium
- (2010) Samuel Sossalla et al. CIRCULATION RESEARCH
- Redox-mediated reciprocal regulation of SERCA and Na+–Ca2+ exchanger contributes to sarcoplasmic reticulum Ca2+ depletion in cardiac myocytes
- (2010) Gabriela M. Kuster et al. FREE RADICAL BIOLOGY AND MEDICINE
- Sudden cardiac death after myocardial infarction in patients with type 2 diabetes
- (2010) M. Juhani Junttila et al. HEART RHYTHM
- Early afterdepolarizations and cardiac arrhythmias
- (2010) James N. Weiss et al. HEART RHYTHM
- Type 2 diabetes mellitus and the risk of sudden cardiac arrest in the community
- (2010) David S. Siscovick et al. REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
- Diabetic cardiomyopathy, causes and effects
- (2010) Sihem Boudina et al. REVIEWS IN ENDOCRINE & METABOLIC DISORDERS
- Nitroxyl Activates SERCA in Cardiac Myocytes via Glutathiolation of Cysteine 674
- (2009) Steve Lancel et al. CIRCULATION RESEARCH
- miR-1 Overexpression Enhances Ca 2+ Release and Promotes Cardiac Arrhythmogenesis by Targeting PP2A Regulatory Subunit B56α and Causing CaMKII-Dependent Hyperphosphorylation of RyR2
- (2009) Dmitry Terentyev et al. CIRCULATION RESEARCH
- Interval Training Normalizes Cardiomyocyte Function, Diastolic Ca 2+ Control, and SR Ca 2+ Release Synchronicity in a Mouse Model of Diabetic Cardiomyopathy
- (2009) Tomas O. Stølen et al. CIRCULATION RESEARCH
- Phospholamban Ablation Rescues Sarcoplasmic Reticulum Ca 2+ Handling but Exacerbates Cardiac Dysfunction in CaMKIIδ C Transgenic Mice
- (2009) Tong Zhang et al. CIRCULATION RESEARCH
- Targeted SERCA2a Gene Expression Identifies Molecular Mechanism and Therapeutic Target for Arrhythmogenic Cardiac Alternans
- (2009) Michael J. Cutler et al. Circulation-Arrhythmia and Electrophysiology
- Diagnosis and Classification of Diabetes Mellitus
- (2009) DIABETES CARE
- Exercise training during diabetes attenuates cardiac ryanodine receptor dysregulation
- (2009) Chun-Hong Shao et al. JOURNAL OF APPLIED PHYSIOLOGY
- Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID Trial), a First-in-Human Phase 1/2 Clinical Trial
- (2009) Brian E. Jaski et al. JOURNAL OF CARDIAC FAILURE
- Calmodulin kinase II–mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice
- (2009) Mihail G. Chelu et al. JOURNAL OF CLINICAL INVESTIGATION
- β-Blocker Use for the Stages of Heart Failure
- (2009) Marc Klapholz MAYO CLINIC PROCEEDINGS
- Optical single-channel resolution imaging of the ryanodine receptor distribution in rat cardiac myocytes
- (2009) David Baddeley et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Diabetic Cardiomyopathy: Insights into Pathogenesis, Diagnostic Challenges, and Therapeutic Options
- (2008) Ashish Aneja et al. AMERICAN JOURNAL OF MEDICINE
- Diabetic cardiomyopathy-associated dysfunction in spatially distinct mitochondrial subpopulations
- (2008) Erinne R. Dabkowski et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Modulation of SR Ca Release by Luminal Ca and Calsequestrin in Cardiac Myocytes: Effects of CASQ2 Mutations Linked to Sudden Cardiac Death
- (2008) Dmitry Terentyev et al. BIOPHYSICAL JOURNAL
- Prevention of Ventricular Arrhythmias With Sarcoplasmic Reticulum Ca 2+ ATPase Pump Overexpression in a Porcine Model of Ischemia Reperfusion
- (2008) Fabrice Prunier et al. CIRCULATION
- Termination of Cardiac Ca 2+ Sparks
- (2008) Aleksey V. Zima et al. CIRCULATION RESEARCH
- Oxidative Stress–Induced Afterdepolarizations and Calmodulin Kinase II Signaling
- (2008) Lai-Hua Xie et al. CIRCULATION RESEARCH
- Cysteine-674 oxidation and degradation of sarcoplasmic reticulum Ca2+ ATPase in diabetic pig aorta
- (2008) Jia Ying et al. FREE RADICAL BIOLOGY AND MEDICINE
- Epidemiology of Sudden Cardiac Death: Clinical and Research Implications
- (2008) Sumeet S. Chugh et al. PROGRESS IN CARDIOVASCULAR DISEASES
- Diabetes as a 'cardiovascular disease equivalent': implications for treatment
- (2008) Markku Laakso Nature clinical practice. Cardiovascular medicine
- Sudden cardiac death: influence of diabetes
- (2007) P. M. Spooner DIABETES OBESITY & METABOLISM
- Short-Term Aerobic Exercise Training in Obese Humans with Type 2 Diabetes Mellitus Improves Whole-Body Insulin Sensitivity through Gains in Peripheral, not Hepatic Insulin Sensitivity
- (2007) Jason J. Winnick et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started