Mechanism Based Quality Control (MBQC) of Herbal Products: A Case Study YIV-906 (PHY906)

The number of intestinal bacteria is not critical for the enhancement of antitumor activity and reduction of intestinal toxicity of irinotecan by the Chinese herbal medicine PHY906 (KD018)

(2015) Wing Lam et al.   BMC Complementary and Alternative Medicine

PHY906(KD018), an adjuvant based on a 1800-year-old Chinese medicine, enhanced the anti-tumor activity of Sorafenib by changing the tumor microenvironment

(2015) Wing Lam et al.   Scientific Reports

Biological ingredient analysis of traditional Chinese medicine preparation based on high-throughput sequencing: the story for Liuwei Dihuang Wan

(2014) Xinwei Cheng et al.   Scientific Reports

First-in-human phase II trial of the botanical formulation PHY906 with capecitabine as second-line therapy in patients with advanced pancreatic cancer

(2013) Muhammad Wasif Saif et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

A novel strategy to evaluate the quality of traditional Chinese medicine based on the correlation analysis of chemical fingerprint and biological effect

(2013) Jing Wang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Preclinical studies of the Chinese Herbal Medicine formulation PHY906 (KD018) as a potential adjunct to radiation therapy

(2012) Sara Rockwell et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Old formula, new Rx: The journey of PHY906 as cancer adjuvant therapy

(2012) Shwu-Huey Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Interaction of a traditional Chinese Medicine (PHY906) and CPT-11 on the inflammatory process in the tumor microenvironment

(2011) Ena Wang et al.   BMC Medical Genomics

A Phase I Study of the Chinese Herbal Medicine PHY906 as a Modulator of Irinotecan-based Chemotherapy in Patients with Advanced Colorectal Cancer

(2011) Shivaani Kummar et al.   Clinical Colorectal Cancer

Phase I study of the botanical formulation PHY906 with capecitabine in advanced pancreatic and other gastrointestinal malignancies

(2010) M. Wasif Saif et al.   PHYTOMEDICINE

The Four-Herb Chinese Medicine PHY906 Reduces Chemotherapy-Induced Gastrointestinal Toxicity

(2010) W. Lam et al.   Science Translational Medicine

A comprehensive platform for quality control of botanical drugs (PhytomicsQC): a case study of Huangqi Tang (HQT) and PHY906

(2010) Robert Tilton et al.   Chinese Medicine

Quality and safety of Chinese herbal medicines guided by a systems biology perspective

(2009) Jiangshan Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY