Synaptotagmin Ca2+ Sensors and Their Spatial Coupling to Presynaptic Cav Channels in Central Cortical Synapses

Molecular Mechanisms of Fast Neurotransmitter Release

(2018) Axel T. Brunger et al.   Annual Review of Biophysics

Synergistic control of neurotransmitter release by different members of the synaptotagmin family

(2018) Kirill E Volynski et al.   CURRENT OPINION IN NEUROBIOLOGY

Models of synaptotagmin-1 triggering Ca2+ -dependent vesicle fusion

(2018) Yongsoo Park et al.   FEBS LETTERS

Synaptotagmin 7 Mediates Both Facilitation and Asynchronous Release at Granule Cell Synapses

(2018) Josef Turecek et al.   JOURNAL OF NEUROSCIENCE

Variations in Ca2+Influx Can Alter Chelator-Based Estimates of Ca2+Channel–Synaptic Vesicle Coupling Distance

(2018) Yukihiro Nakamura et al.   JOURNAL OF NEUROSCIENCE

Apparent calcium dependence of vesicle recruitment

(2018) Andreas Ritzau-Jost et al.   JOURNAL OF PHYSIOLOGY-LONDON

Ultrafast glutamate sensors resolve high-frequency release at Schaffer collateral synapses

(2018) Nordine Helassa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Munc13-3 Is Required for the Developmental Localization of Ca 2+ Channels to Active Zones and the Nanopositioning of Ca v 2.1 Near Release Sensors

(2018) Valentin Kusch et al.   Cell Reports

Stability, affinity, and chromatic variants of the glutamate sensor iGluSnFR

(2018) Jonathan S. Marvin et al.   NATURE METHODS

The primed SNARE–complexin–synaptotagmin complex for neuronal exocytosis

(2017) Qiangjun Zhou et al.   NATURE

Synaptotagmin 7 confers frequency invariance onto specialized depressing synapses

(2017) Josef Turecek et al.   NATURE

Synaptotagmins: That’s Why So Many

(2017) Chong Chen et al.   NEURON

The Mechanisms and Functions of Synaptic Facilitation

(2017) Skyler L. Jackman et al.   NEURON

Synaptotagmin-7-Mediated Asynchronous Release Boosts High-Fidelity Synchronous Transmission at a Central Synapse

(2017) Fujun Luo et al.   NEURON

Kinetics of Releasable Synaptic Vesicles and Their Plastic Changes at Hippocampal Mossy Fiber Synapses

(2017) Mitsuharu Midorikawa et al.   NEURON

Synaptotagmin-1- and Synaptotagmin-7-Dependent Fusion Mechanisms Target Synaptic Vesicles to Kinetically Distinct Endocytic Pathways

(2017) Ying C. Li et al.   NEURON

Exceptionally tight membrane-binding may explain the key role of the synaptotagmin-7 C2A domain in asynchronous neurotransmitter release

(2017) Rashmi Voleti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptotagmin 2 Is the Fast Ca 2+ Sensor at a Central Inhibitory Synapse

(2017) Chong Chen et al.   Cell Reports

Frequency-dependent mobilization of heterogeneous pools of synaptic vesicles shapes presynaptic plasticity

(2017) Frédéric Doussau et al.   eLife

High-Probability Neurotransmitter Release Sites Represent an Energy-Efficient Design

(2016) Zhongmin Lu et al.   CURRENT BIOLOGY

The calcium sensor synaptotagmin 7 is required for synaptic facilitation

(2016) Skyler L. Jackman et al.   NATURE

Should I stop or should I go? The role of complexin in neurotransmitter release

(2016) Thorsten Trimbuch et al.   NATURE REVIEWS NEUROSCIENCE

A Synaptotagmin Isoform Switch during the Development of an Identified CNS Synapse

(2016) Olexiy Kochubey et al.   NEURON

Actin- and Myosin-Dependent Vesicle Loading of Presynaptic Docking Sites Prior to Exocytosis

(2016) Takafumi Miki et al.   NEURON

RIM-binding protein 2 regulates release probability by fine-tuning calcium channel localization at murine hippocampal synapses

(2016) M. Katharina Grauel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Nanophysiology of Fast Transmitter Release

(2016) Elise F. Stanley   TRENDS IN NEUROSCIENCES

Developmental Tightening of Cerebellar Cortical Synaptic Influx-Release Coupling

(2015) D. Baur et al.   JOURNAL OF NEUROSCIENCE

RIM-BPs Mediate Tight Coupling of Action Potentials to Ca 2+ -Triggered Neurotransmitter Release

(2015) Claudio Acuna et al.   NEURON

Nanoscale Distribution of Presynaptic Ca 2+ Channels and Its Impact on Vesicular Release during Development

(2015) Yukihiro Nakamura et al.   NEURON

Reduced endogenous Ca2+buffering speeds active zone Ca2+signaling

(2015) Igor Delvendahl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A use-dependent increase in release sites drives facilitation at calretinin-deficient cerebellar parallel-fiber synapses

(2015) Simone Brachtendorf et al.   Frontiers in Cellular Neuroscience

Presynaptic nanodomains: a tale of two synapses

(2015) Lu-Yang Wang et al.   Frontiers in Cellular Neuroscience

The Molecular Machinery of Neurotransmitter Release (Nobel Lecture)

(2014) Thomas C. Südhof   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Munc13-3 Superprimes Synaptic Vesicles at Granule Cell-to-Basket Cell Synapses in the Mouse Cerebellum

(2014) S. Ishiyama et al.   JOURNAL OF NEUROSCIENCE

Ultrafast Action Potentials Mediate Kilohertz Signaling at a Central Synapse

(2014) Andreas Ritzau-Jost et al.   NEURON

Loose Coupling Between Ca2+ Channels and Release Sensors at a Plastic Hippocampal Synapse

(2014) N. P. Vyleta et al.   SCIENCE

Synaptotagmin 7 functions as a Ca2+-sensor for synaptic vesicle replenishment

(2014) Huisheng Liu et al.   eLife

Nanodomain coupling explains Ca2+ independence of transmitter release time course at a fast central synapse

(2014) Itaru Arai et al.   eLife

Molecular Mechanisms for Synchronous, Asynchronous, and Spontaneous Neurotransmitter Release

(2013) Pascal S. Kaeser et al.   Annual Review of Physiology

Paired-pulse facilitation at recurrent Purkinje neuron synapses is independent of calbindin and parvalbumin during high-frequency activation

(2013) Grit Bornschein et al.   JOURNAL OF PHYSIOLOGY-LONDON

Differential triggering of spontaneous glutamate release by P/Q-, N- and R-type Ca2+ channels

(2013) Yaroslav S Ermolyuk et al.   NATURE NEUROSCIENCE

Synaptotagmin-1 and Synaptotagmin-7 Trigger Synchronous and Asynchronous Phases of Neurotransmitter Release

(2013) Taulant Bacaj et al.   NEURON

Neurotransmitter Release: The Last Millisecond in the Life of a Synaptic Vesicle

(2013) Thomas C. Südhof   NEURON

Nanodomain Coupling at an Excitatory Cortical Synapse

(2012) Hartmut Schmidt et al.   CURRENT BIOLOGY

Adaptation of Granule Cell to Purkinje Cell Synapses to High-Frequency Transmission

(2012) A. M. Valera et al.   JOURNAL OF NEUROSCIENCE

The Number and Organization of Ca2+ Channels in the Active Zone Shapes Neurotransmitter Release from Schaffer Collateral Synapses

(2012) A. Scimemi et al.   JOURNAL OF NEUROSCIENCE

Release probability of hippocampal glutamatergic terminals scales with the size of the active zone

(2012) Noemi Holderith et al.   NATURE NEUROSCIENCE

The Presynaptic Active Zone

(2012) Thomas C. Südhof   NEURON

Short-term plasticity constrains spatial organization of a hippocampal presynaptic terminal

(2012) S. Nadkarni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RIM Proteins Tether Ca2+ Channels to Presynaptic Active Zones via a Direct PDZ-Domain Interaction

(2011) Pascal S. Kaeser et al.   CELL

How the 'slow' Ca2+ buffer parvalbumin affects transmitter release in nanodomain-coupling regimes

(2011) Emmanuel Eggermann et al.   NATURE NEUROSCIENCE

Nanodomain coupling between Ca2+ channels and sensors of exocytosis at fast mammalian synapses

(2011) Emmanuel Eggermann et al.   NATURE REVIEWS NEUROSCIENCE

Synaptotagmin Increases the Dynamic Range of Synapses by Driving Ca2+-Evoked Release and by Clamping a Near-Linear Remaining Ca2+ Sensor

(2011) Olexiy Kochubey et al.   NEURON

Regulation of transmitter release by Ca2+ and synaptotagmin: insights from a large CNS synapse

(2011) Olexiy Kochubey et al.   TRENDS IN NEUROSCIENCES

Septins Regulate Developmental Switching from Microdomain to Nanodomain Coupling of Ca2+ Influx to Neurotransmitter Release at a Central Synapse

(2010) Yi-Mei Yang et al.   NEURON

The Ca2+Affinity of Synaptotagmin 1 Is Markedly Increased by a Specific Interaction of Its C2B Domain with Phosphatidylinositol 4,5-Bisphosphate

(2009) Anand Radhakrishnan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synaptic Vesicles in Mature Calyx of Held Synapses Sense Higher Nanodomain Calcium Concentrations during Action Potential-Evoked Glutamate Release

(2009) L.-Y. Wang et al.   JOURNAL OF NEUROSCIENCE

Developmental regulation of the intracellular Ca2+sensitivity of vesicle fusion and Ca2+-secretion coupling at the rat calyx of Held

(2009) Olexiy Kochubey et al.   JOURNAL OF PHYSIOLOGY-LONDON

A small number of open Ca2+ channels trigger transmitter release at a central GABAergic synapse

(2009) Iancu Bucurenciu et al.   NATURE NEUROSCIENCE

A General Model of Synaptic Transmission and Short-Term Plasticity

(2009) Bin Pan et al.   NEURON

Membrane Fusion: Grappling with SNARE and SM Proteins

(2009) T. C. Sudhof et al.   SCIENCE

Action potential evoked transmitter release in central synapses: insights from the developing calyx of Held

(2009) Lu-Yang Wang et al.   Molecular Brain

Two Ca2+-Dependent Steps Controlling Synaptic Vesicle Fusion and Replenishment at the Cerebellar Basket Cell Terminal

(2008) Takeshi Sakaba   NEURON

Nanodomain Coupling between Ca2+ Channels and Ca2+ Sensors Promotes Fast and Efficient Transmitter Release at a Cortical GABAergic Synapse

(2008) Iancu Bucurenciu et al.   NEURON