IRS-1 increases TAZ expression and promotes osteogenic differentiation in rat bone marrow mesenchymal stem cells

Proliferation of hepatic stellate cells, mediated by YAP and TAZ, contributes to liver repair and regeneration after liver ischemia-reperfusion injury

(2018) Takanori Konishi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Osteocalcin Mediates Biomineralization during Osteogenic Maturation in Human Mesenchymal Stromal Cells

(2017) Yu-Tzu Tsao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Polycystin-1 interacts with TAZ to stimulate osteoblastogenesis and inhibit adipogenesis

(2017) Zhousheng Xiao et al.   JOURNAL OF CLINICAL INVESTIGATION

Mechanobiology of YAP and TAZ in physiology and disease

(2017) Tito Panciera et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanical Stress Regulates Osteogenesis and Adipogenesis of Rat Mesenchymal Stem Cells through PI3K/Akt/GSK-3β/β-Catenin Signaling Pathway

(2017) Fanglong Song et al.   Biomed Research International

Inhibiting PPARγ by erythropoietin while upregulating TAZ by IGF1 synergistically promote osteogenic differentiation of mesenchymal stem cells

(2016) Jianwei Zhou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TAZ promotes cell growth and inhibits Celastrol-induced cell apoptosis

(2016) S. Wang et al.   BIOSCIENCE REPORTS

Lentivirus-TAZ Administration Alleviates Osteoporotic Phenotypes in the Femoral Neck of Ovariectomized Rats

(2016) Zhanhai Yin et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Comparison of fetal cartilage-derived progenitor cells isolated at different developmental stages in a rat model

(2016) Mijin Kim et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Insulin receptor substrate-1 time-dependently regulates bone formation by controlling collagen Iα2 expression via miR-342

(2016) Yue Guo et al.   FASEB JOURNAL

Down-regulation of Insulin Receptor Substrate 1 during Hyperglycemia Induces Vascular Smooth Muscle Cell Dedifferentiation

(2016) Gang Xi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IRS-1 Functions as a Molecular Scaffold to Coordinate IGF-I/IGFBP-2 Signaling During Osteoblast Differentiation

(2016) Gang Xi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Snail/Slug binding interactions with YAP/TAZ control skeletal stem cell self-renewal and differentiation

(2016) Yi Tang et al.   NATURE CELL BIOLOGY

Fibrinogen Induces RUNX2 Activity and Osteogenic Development from Human Pluripotent Stem Cells

(2016) Fahad Kidwai et al.   STEM CELLS

MiR-384 regulated IRS1 expression and suppressed cell proliferation of human hepatocellular carcinoma

(2016) Yue-yuan Lai et al.   TUMOR BIOLOGY

The Hippo transducer TAZ promotes cell proliferation and tumor formation of glioblastoma cells through EGFR pathway

(2016) Rui Yang et al.   Oncotarget

TGFβ-induced switch from adipogenic to osteogenic differentiation of human mesenchymal stem cells: identification of drug targets for prevention of fat cell differentiation

(2016) Everardus J. van Zoelen et al.   Stem Cell Research & Therapy

Human mesenchymal stem cells - current trends and future prospective

(2015) Imran Ullah et al.   BIOSCIENCE REPORTS

Bone Health and Osteoporosis

(2015) Beatrice C. Lupsa et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

IL-13 receptor α2 is a negative prognostic factor in human lung cancer and stimulates lung cancer growth in mice

(2015) Mian Xie et al.   Oncotarget

Osteoblast Proliferation is Enhanced upon the Insulin Receptor Substrate 1 Overexpression via PI3K Signaling Leading to Down-regulation of NFκB and BAX Pathway

(2014) H. Ma et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

IGF1 promotes osteogenic differentiation of mesenchymal stem cells derived from rat bone marrow by increasing TAZ expression

(2013) Peng Xue et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Knockdown of insulin receptor substrate 1 reduces proliferation and downregulates Akt/mTOR and MAPK pathways in K562 cells

(2011) João Agostinho Machado-Neto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Watching osteogenesis: Life monitoring of osteogenic differentiation using an osteocalcin reporter

(2011) Anne-Kathrin Born et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Insulin Receptor Signaling in Osteoblasts Regulates Postnatal Bone Acquisition and Body Composition

(2010) Keertik Fulzele et al.   CELL