Review
Clinical Neurology
Somayye Nadi Ravandi, Ebrahim Kouchaki, Fatemeh Sadat Asgarian
Summary: This study conducted a systematic review of 32 studies and found that the prevalence of hallucinations in Parkinson's patients is 28%. The highest prevalence was in developing countries at 34%, and in developed countries it was 27%. The prevalence in men was 30% and in women it was 23%. It is recommended to check for hallucinations in Parkinson's patients during every visit and provide appropriate treatment.
NEUROLOGICAL SCIENCES
(2023)
Review
Cell Biology
Chien -Tai Hong, Jia-Hung Chen, Tsai-Wei Huang
Summary: This study investigated the effects of probiotics on Parkinson's disease patients and found that probiotics significantly alleviated constipation symptoms and may have systemic effects on inflammation and metabolism.
Review
Radiology, Nuclear Medicine & Medical Imaging
Se Jin Cho, Yun Jung Bae, Jong-Min Kim, Donghyun Kim, Sung Hyun Baik, Leonard Sunwoo, Byung Se Choi, Jae Hyoung Kim
Summary: Neuromelanin-sensitive magnetic resonance imaging showed good diagnostic performance in discriminating patients with Parkinson's disease from healthy controls. Factors such as disease duration, imaging parameters, and segmentation methods were found to influence the diagnostic performance. Further investigations comparing these factors and optimizing parameters are necessary to improve diagnostic accuracy.
EUROPEAN RADIOLOGY
(2021)
Review
Medicine, General & Internal
Cong Gai, Tianyao Qiang, Yuxin Zhang, Yuan Chai, Wandi Feng, Hongmei Sun
Summary: This study aims to evaluate the efficacy and safety of electroacupuncture in Parkinson's disease patients through a meta-analysis. The results will comprehensively assess various outcomes to determine the effectiveness of EA in treating PD.
Article
Clinical Neurology
Antonio Terracciano, Damaris Aschwanden, Yannick Stephan, Antonio Cerasa, Luca Passamonti, Nicola Toschi, Angelina R. Sutin
Summary: Neuroticism is consistently associated with a higher risk of incident Parkinson's disease, as evidenced by a large cohort study from the UK Biobank and a meta-analysis of prospective studies.
MOVEMENT DISORDERS
(2021)
Review
Cell Biology
Hanna M. Gavelin, Magdalena E. Domellof, Isabella Leung, Anna Stigsdotter Neely, Nathalie H. Launder, Leila Nategh, Carsten Finke, Amit Lampit
Summary: Cognitive impairment is a common symptom in Parkinson's disease (PD) patients, and computerized cognitive training (CCT) may have beneficial effects on their cognitive and psychosocial functioning. This study found that CCT had a significant positive effect on overall cognitive function and clinical measures of global cognition in PD patients, especially those with mild cognitive impairment. The dose of CCT and the presence of mild cognitive impairment in PD patients were associated with larger effect sizes. There was no significant difference in efficacy between home-based and supervised training.
AGEING RESEARCH REVIEWS
(2022)
Review
Clinical Neurology
Yong Qi Leong, Shaun Wen Huey Lee, Khuen Yen Ng
Summary: The study revealed that Parkinson's disease patients have lower risks of certain cancers but higher risks of melanoma and brain cancer. Additionally, there were negative associations between PD patients and risks of colon cancer, rectal cancer, and non-Hodgkin lymphoma. Further research is needed to explore the underlying mechanisms between PD and cancers.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Article
Medicine, General & Internal
Jia-Ning Jin, Xian Liu, Ming-Juan Li, Xin-Ling Bai, An-Mu Xie
Summary: This meta-analysis study suggests that PD patients have higher levels of total bilirubin and direct bilirubin, with no significant relationship found between indirect bilirubin and PD. Subgroup analysis based on ethnicity indicates that Caucasians with PD have higher serum total bilirubin levels. These findings suggest that bilirubin may play a role in the pathogenesis of PD and could potentially be used as a biochemical marker for diagnosis and treatment.
CHINESE MEDICAL JOURNAL
(2021)
Review
Public, Environmental & Occupational Health
Yujia Zhao, Anushree Ray, Lutzen Portengen, Roel Vermeulen, Susan Peters
Summary: This study systematically reviewed the literature on the relationship between metal exposure and Parkinson's disease (PD) risk and evaluated the overall quality of each study and exposure assessment method. The results showed that concentrations of copper, iron, and zinc were lower in PD cases, while concentrations of magnesium and zinc were higher. Cumulative lead levels were associated with increased risk of PD. However, the current evidence is limited and high-quality studies are needed to better understand the role of metals in PD etiology.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2023)
Review
Clinical Neurology
L. McMahon, C. Blake, O. Lennon
Summary: This systematic review identifies the current evidence to support nonpharmacological interventions to improve respiratory impairments in individuals with Parkinson's disease. Various nonpharmacological interventions, such as training, respiratory muscle strength training, aerobic exercise, qigong, and yoga, have been shown to improve respiratory muscle strength and peak expiratory flow in PD patients. Further studies are needed to target respiratory dysfunction and examine the relationship between respiratory dysfunction and morbidity and mortality rates in PD.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Review
Medicine, General & Internal
Yuqi Yang, Tong Zhang, Lixu Liu, Lei Shan, Xueyan Hu, Lingyu Yang, Fei Gao, Xiaoli Wu, Hanzhi Li
Summary: The efficacy and safety of botulinum toxin (BTX) for motor dysfunction in Parkinson's disease (PD) were evaluated through a systematic review and meta-analysis. The findings suggest that BTX treatment may not alleviate motor symptoms significantly, but it can benefit pain alleviation and functional mobility improvement.
Review
Geriatrics & Gerontology
Yujia Qian, Xueying Fu, Haoyang Zhang, Yong Yang, Guotuan Wang
Summary: This study aimed to compare, rank, and evaluate 24 exercise types that improve postural instability in patients with Parkinson's disease. The results showed that body-weight support treadmill training, aquatic exercise, Pilates, balance and gait training with the external cue or attention, and robotic assisted gait balance may be the most effective treatments for adults with Parkinson's disease, but the confidence in evidence was low.
Review
Medicine, General & Internal
Yonghui Hou, Baile Ning, Yamin Liu, Ying Liu, Wenbin Fu, Zehuai Wen
Summary: This systematic review will evaluate the effectiveness and safety of moxibustion therapy in the treatment of Parkinson's disease (PD). The findings may provide further evidence to support the use of moxibustion by clinicians.
Review
Clinical Neurology
Ahmed Negida, Hazem S. Ghaith, Salma Yousry Fala, Hussien Ahmed, Eshak Bahbah, Mahmoud Ahmed Ebada, Mohamed Abd Elalem Aziz
Summary: This meta-analysis of six randomized controlled trials found that Mavoglurant was not superior to placebo in treating levodopa-induced dyskinesia in patients with Parkinson's Disease.
NEUROLOGICAL SCIENCES
(2021)
Review
Oncology
Danuta Krasowska, Agnieszka Gerkowicz, Radoslaw Mlak, Milena Leziak, Teresa Malecka-Massalska, Dorota Krasowska
Summary: Non-melanoma skin cancers (NMSCs) are the most common cancers among fair-skinned people. Patients with Parkinson's disease (PD) have an increased risk of developing NMSCs, particularly basal cell carcinoma. Further research is needed to explore the mechanisms underlying the relationship between PD and NMSCs.
Review
Biotechnology & Applied Microbiology
Zonglei Zhou, Ruzhen Zhou, Kunpeng Li, Wen Wei, Zengqiao Zhang, Yan Zhu, Rongsheng Luan
BIOMED RESEARCH INTERNATIONAL
(2019)
Review
Endocrinology & Metabolism
Shujuan Yang, Xiao Zhang, Ping Feng, Tong Wu, Ruochen Tian, Donglan Zhang, Li Zhao, Chenghan Xiao, Zonglei Zhou, Fang He, Guo Cheng, Peng Jia
Summary: The lack of access to fruit/vegetable markets (FVMs) has been considered a risk factor for childhood obesity, but the association between FVM access and weight-related behaviors remains inconclusive. More research is needed to fill this important gap in knowledge and provide better guidance for public health interventions.
Review
Rehabilitation
Zonglei Zhou, Ruzhen Zhou, Wen Wei, Rongsheng Luan, Kunpeng Li
Summary: The systematic review included 17 studies with 598 participants. Music-based movement therapy significantly improved motor function, balance, gait, freezing of gait, walking velocity, and mental health, but had no significant effects on gait cadence, stride length, and quality of life.
CLINICAL REHABILITATION
(2021)
Article
Medicine, Research & Experimental
Kun-Peng Li, Zong-Lei Zhou, Ru-Zhen Zhou, Yan Zhu, Zeng-Qiao Zhang
Summary: The use of music exercise therapy has shown promising results in improving freezing of gait in Parkinson's patients, and this study aims to validate its clinical efficacy. Through a three-arm randomized controlled trial with 81 inpatients, the study will assess changes in gait and limb motor function after 4 weeks of intervention, with the goal of affirming the clinical application of this therapy in Parkinson's disease management.
Article
Nutrition & Dietetics
Zonglei Zhou, Kunpeng Li, Xianzhi Li, Rongsheng Luan, Ruzhen Zhou
Summary: This study shows that BMI, waist circumference, and WHtR equally predict the development of hyperuricemia, and weight loss and waist circumference reduction are favorable in preventing hyperuricemia. Participants with weight loss of >= 4 kg or waist circumference loss of >= 6 cm had a lower risk of hyperuricemia, while weight gain increased the risk.
NUTRITION & METABOLISM
(2021)
Article
Psychiatry
Zonglei Zhou, Yao Wang, Ping Feng, Tongxin Li, Jacob Kraemer Tebes, Rongsheng Luan, Yu Yu
Summary: The study found that the level of caregiving knowledge and skills is positively correlated with the psychological well-being and active coping strategies of primary family caregivers of people living with schizophrenia. However, caregivers with different levels of caregiving knowledge and skills showed no significant differences in caregiver burden and coping styles.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Public, Environmental & Occupational Health
Xianzhi Li, Yajie Li, Xiangyi Xing, Yu Liu, Zonglei Zhou, Shunjin Liu, Yunyun Tian, Qucuo Nima, Li Yin, Bin Yu
Summary: This study found that long-term exposure to high altitudes has a negative impact on the nutritional status of children under 5 years old. With every 1000 m increase in altitude, the height-for-age and weight-for-age scores decrease, while the risk of stunting and underweight increases. The effects of high altitudes on rural children's underweight are greater than those on urban children.
PUBLIC HEALTH NUTRITION
(2023)
Article
Geriatrics & Gerontology
Kun-peng Li, Zeng-qiao Zhang, Zong-lei Zhou, Jian-qing Su, Xian-hua Wu, Bo-han Shi, Jian-guang Xu
Summary: The study aimed to explore the effect of MMT on FOG in PD patients. Results showed that MMT group had reduced FOG and improved comprehensive motor function compared to the control and exercise therapy groups.
FRONTIERS IN AGING NEUROSCIENCE
(2022)
Article
Public, Environmental & Occupational Health
Wen Wei, Lan Xia, Jianlin Wu, Zonglei Zhou, Wenqiang Zhang, Rongsheng Luan
Summary: This study investigates the risk factors of tuberculosis (TB) and predicts the incidence of TB infection across different age groups in Sichuan Province, China. The study finds that illiteracy rate and average pressure are risk factors for TB, while the number of families with minimum living standard guarantee and average wind speed are protective factors. The forecast shows that the incidence of TB in male patients aged 0-14 and 15-24 years will continue to increase, and the incidence in female patients aged 0-14 and >=65 years will increase rapidly by 2035 in Sichuan.
JMIR PUBLIC HEALTH AND SURVEILLANCE
(2023)
Article
Biotechnology & Applied Microbiology
Zonglei Zhou, Huaiming Yi, Qingrong Zhou, Luqi Wang, Yue Zhu, Weibing Wang, Zhengwe Liu, Haiyan Xiong
Summary: This study investigated the evolution and epidemic success of Mycobacterium tuberculosis isolates in eastern China, revealing the prevalence of resistance mutations and their impact on transmission. The study found that mutations in genes associated with drug resistance and tolerance significantly contribute to the epidemiological transmission of pre-XDR strains.
Review
Neurosciences
Kun-Peng Li, Jia-Jia Wu, Zong-Lei Zhou, Dong-Sheng Xu, Mou-Xiong Zheng, Xu-Yun Hua, Jian-Guang Xu
Summary: Stroke, characterized by high morbidity, mortality, and disability, poses a serious threat to human life and health due to the sudden blockage or rupture of brain vessels causing cerebral hypoxia. Noninvasive brain stimulation (NIBS), such as rTMS and tDCS, has shown potential in post-stroke rehabilitation by regulating the excitability of neurons. However, the lack of standardized protocols and the variation in parameters limit its application in this area.
Article
Obstetrics & Gynecology
Zonglei Zhou, Yu Yu, Ruzhen Zhou, Rongsheng Luan, Kunpeng Li
Summary: Short sleep duration and depression are independently associated with increased risk of falls among postmenopausal women in China. Furthermore, short sleep duration combined with either no or long napping, as well as short sleep duration combined with depression, are jointly correlated with a higher likelihood of experiencing falls.
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY
(2021)
Review
Rehabilitation
Zonglei Zhou, Ruzhen Zhou, Kunpeng Li, Yan Zhu, Zengqiao Zhang, Yun Luo, Rongsheng Luan
JOURNAL OF REHABILITATION MEDICINE
(2019)
Article
Medicine, Research & Experimental
Sitian He, Songcheng Yu, Zonglei Zhou, Chongjian Wang, Yongjun Wu, Wenjie Li
BIOMEDICAL REPORTS
(2018)