Crocetin attenuates inflammation and amyloid-β accumulation in APPsw transgenic mice

Pharmacokinetic Properties of Saffron and its Active Components

(2017) Azar Hosseini et al.   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

Saffron and its derivatives, crocin, crocetin and safranal: a patent review

(2017) Maryam Rameshrad et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Protective Roles of Monsonia angustifolia and Its Active Compounds in Experimental Models of Alzheimer’s Disease

(2017) Yoon Sun Chun et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Trans -crocetin improves amyloid-β degradation in monocytes from Alzheimer's Disease patients

(2017) Roberto Tiribuzi et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

The Cardiovascular Pharmacology of Nonsteroidal Anti-Inflammatory Drugs

(2017) Tilo Grosser et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

NF-κB as a Key Mediator of Brain Inflammation in Alzheimer’s Disease

(2017) Chul Ju Hwang et al.   CNS & Neurological Disorders-Drug Targets

Crocetin Inhibits Lipopolysaccharide-Induced Inflammatory Response in Human Umbilical Vein Endothelial Cells

(2016) Lei Song et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Alzheimer's disease

(2016) Philip Scheltens et al.   LANCET

Non-Steroidal Anti-Inflammatory Drugs as a Treatment for Alzheimer’s Disease: A Systematic Review and Meta-Analysis of Treatment Effect

(2015) Marina Miguel-Álvarez et al.   DRUGS & AGING

A review on Alzheimer's disease pathophysiology and its management: an update

(2015) Anil Kumar et al.   Pharmacological Reports

Alzheimer's disease

(2015) Colin L. Masters et al.   Nature Reviews Disease Primers

Serum Cytokine Profile in Alzheimer's Disease Patients After Ingestion of an Antioxidant Beverage

(2014) J.M. Rubio-Perez et al.   CNS & Neurological Disorders-Drug Targets

Crocetin Attenuates Spatial Learning Dysfunction and Hippocampal Injury in a Model of Vascular Dementia

(2013) Faezeh Tashakori-Sabzevar et al.   CURRENT NEUROVASCULAR RESEARCH

Object recognition test in mice

(2013) Marianne Leger et al.   Nature Protocols

Inflammation in Alzheimer Disease--A Brief Review of the Basic Science and Clinical Literature

(2013) T. Wyss-Coray et al.   Cold Spring Harbor Perspectives in Medicine

Avicenna's (Ibn Sina) the Canon of Medicine and Saffron (Crocus sativus): A Review

(2012) Hossein Hosseinzadeh et al.   PHYTOTHERAPY RESEARCH

Crocetin inhibits beta-amyloid fibrillization and stabilizes beta-amyloid oligomers

(2011) Joon Ho Ahn et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Crocetin reduces the oxidative stress induced reactive oxygen species in the stroke-prone spontaneously hypertensive rats (SHRSPs) brain

(2011) Fumihiko Yoshino et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Role of p53 in Neurodegenerative Diseases

(2011) J. Robert Chang et al.   Neurodegenerative Diseases

Morris Water Maze Test for Learning and Memory Deficits in Alzheimer's Disease Model Mice

(2011) Kelley Bromley-Brits et al.   Jove-Journal of Visualized Experiments

Anti-inflammatory effects of crocin and crocetin in rat brain microglial cells

(2010) Kyong Nyon Nam et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

ORIGINAL ARTICLE: Saffron in the treatment of patients with mild to moderate Alzheimer’s disease: a 16-week, randomized and placebo-controlled trial

(2010) S. Akhondzadeh et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

A 22-week, multicenter, randomized, double-blind controlled trial of Crocus sativus in the treatment of mild-to-moderate Alzheimer’s disease

(2009) Shahin Akhondzadeh et al.   PSYCHOPHARMACOLOGY

Microglial Dysfunction and Defective  -Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice

(2008) S. E. Hickman et al.   JOURNAL OF NEUROSCIENCE