PGC-1α 4 gene expression is suppressed by the IL-6-MEK-ERK 1/2 MAPK signalling axis and altered by resistance exercise, obesity and muscle injury

Translational machinery of mitochondrial mRNA is promoted by physical activity in Western diet-induced obese mice

(2016) D. E. Lee et al.   Acta Physiologica

Age-related deficits in skeletal muscle recovery following disuse are associated with neuromuscular junction instability and ER stress, not impaired protein synthesis

(2016) Leslie M. Baehr et al.   Aging-US

microRNA-16 Is Downregulated During Insulin Resistance and Controls Skeletal Muscle Protein Accretion

(2016) David E. Lee et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Differential effects of leucine supplementation in young and aged mice at the onset of skeletal muscle regeneration

(2016) Richard A. Perry et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Diet-induced obesity alters anabolic signalling in mice at the onset of skeletal muscle regeneration

(2015) L. A. Brown et al.   Acta Physiologica

Mechanisms of Cachexia in Chronic Disease States

(2015) Tadashi Yoshida et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Mechanisms and Regulation of Alternative Pre-mRNA Splicing

(2015) Yeon Lee et al.   Annual Review of Biochemistry

Quality of life and physical components linked to sarcopenia: The SarcoPhAge study

(2015) C. Beaudart et al.   EXPERIMENTAL GERONTOLOGY

Age-associated declines in muscle mass, strength, power, and physical performance: impact on fear of falling and quality of life

(2015) A. Trombetti et al.   OSTEOPOROSIS INTERNATIONAL

Tumor Necrosis Factor Alpha and Insulin-Like Growth Factor 1 Induced Modifications of the Gene Expression Kinetics of Differentiating Skeletal Muscle Cells

(2015) Swanhild U. Meyer et al.   PLoS One

Hypermetabolism and symptom burden in advanced cancer patients evaluated in a cachexia clinic

(2015) Rony Dev et al.   Journal of Cachexia Sarcopenia and Muscle

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance

(2015) James Andrew McCubrey et al.   Oncotarget

Impaired exercise-induced mitochondrial biogenesis in the obese Zucker rat, despite PGC-1α induction, is due to compromised mitochondrial translation elongation

(2014) Nicholas P. Greene et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Treadmill Training Increases SIRT-1 and PGC-1αProtein Levels and AMPK Phosphorylation in Quadriceps of Middle-Aged Rats in an Intensity-Dependent Manner

(2014) Nara R. C. Oliveira et al.   MEDIATORS OF INFLAMMATION

Effect of Exercise Intensity on Isoform-Specific Expressions of NT-PGC-1αmRNA in Mouse Skeletal Muscle

(2014) Xingyuan Wen et al.   Biomed Research International

Role of interleukin-6 in cachexia

(2014) Aditi A. Narsale et al.   Current Opinion in Supportive and Palliative Care

Muscle mTORC1 suppression by IL-6 during cancer cachexia: a role for AMPK

(2013) James P. White et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Abnormal protein turnover and anabolic resistance to exercise in sarcopenic obesity

(2013) Mats I. Nilsson et al.   FASEB JOURNAL

Heightened muscle inflammation susceptibility may impair regenerative capacity in aging humans

(2013) Edward K. Merritt et al.   JOURNAL OF APPLIED PHYSIOLOGY

Cytokine Response of Cultured Skeletal Muscle Cells Stimulated with Proinflammatory Factors Depends on Differentiation Stage

(2013) Matej Podbregar et al.   TheScientificWorldJOURNAL

JAK/STAT3 pathway inhibition blocks skeletal muscle wasting downstream of IL-6 and in experimental cancer cachexia

(2012) Andrea Bonetto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

A PGC-1α Isoform Induced by Resistance Training Regulates Skeletal Muscle Hypertrophy

(2012) Jorge L. Ruas et al.   CELL

TNFalpha- and tumor-induced skeletal muscle atrophy involves sphingolipid metabolism

(2012) Joffrey De Larichaudy et al.   Skeletal Muscle

Skeletal muscle mass recovery from atrophy in IL-6 knockout mice

(2011) T. A. Washington et al.   Acta Physiologica

Decreased limb muscle and increased central adiposity are associated with 5-year all-cause mortality in HIV infection

(2011) Rebecca Scherzer et al.   AIDS

IL-6 and soluble IL-6 receptor stimulate the production of MMPs and their inhibitors via JAK–STAT and ERK–MAPK signalling in human chondrocytes

(2011) Yukiko Aida et al.   CELL BIOLOGY INTERNATIONAL

The Regulation of Skeletal Muscle Protein Turnover during the Progression of Cancer Cachexia in the ApcMin/+ Mouse

(2011) James P. White et al.   PLoS One

The effect of exercise on IL-6-induced cachexia in theApcMin/+mouse

(2011) Melissa J. Puppa et al.   Journal of Cachexia Sarcopenia and Muscle

Insulin resistance syndrome blunts the mitochondrial anabolic response following resistance exercise

(2010) Mats I. Nilsson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Muscle oxidative capacity during IL-6-dependent cancer cachexia

(2010) James P. White et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Tumor Necrosis Factor-α Regulates Distinct Molecular Pathways and Gene Networks in Cultured Skeletal Muscle Cells

(2010) Shephali Bhatnagar et al.   PLoS One

Overload-induced skeletal muscle extracellular matrix remodelling and myofibre growth in mice lacking IL-6

(2009) J. P. White et al.   Acta Physiologica

Interleukin-6 Attenuates Insulin-Mediated Increases in Endothelial Cell Signaling but Augments Skeletal Muscle Insulin Action via Differential Effects on Tumor Necrosis Factor-  Expression

(2009) D. Y.C. Yuen et al.   DIABETES

Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6

(2008) Bente K. Pedersen et al.   PHYSIOLOGICAL REVIEWS