Dlk1-Dio3 locus-derived lncRNAs perpetuate postmitotic motor neuron cell fate and subtype identity

Visualization of Motor Axon Navigation and Quantification of Axon Arborization In Mouse Embryos Using Light Sheet Fluorescence Microscopy

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Long Noncoding RNA MEG3 Is an Epigenetic Determinant of Oncogenic Signaling in Functional Pancreatic Neuroendocrine Tumor Cells

(2017) Sucharitha Iyer et al.   MOLECULAR AND CELLULAR BIOLOGY

Causal role for inheritance of H3K27me3 in maintaining the OFF state of a Drosophila HOX gene

(2017) Rory T. Coleman et al.   SCIENCE

MicroRNA filters Hox temporal transcription noise to confer boundary formation in the spinal cord

(2017) Chung-Jung Li et al.   Nature Communications

The Properties of Long Noncoding RNAs That Regulate Chromatin

(2016) Michael Rutenberg-Schoenberg et al.   Annual Review of Genomics and Human Genetics

Comparison of normalization and differential expression analyses using RNA-Seq data from 726 individual Drosophila melanogaster

(2016) Yanzhu Lin et al.   BMC GENOMICS

The Dlk1-Gtl2 Locus Preserves LT-HSC Function by Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism

(2016) Pengxu Qian et al.   Cell Stem Cell

Expression of Terminal Effector Genes in Mammalian Neurons Is Maintained by a Dynamic Relay of Transient Enhancers

(2016) Ho Sung Rhee et al.   NEURON

Hox Proteins Coordinate Motor Neuron Differentiation and Connectivity Programs through Ret/Gfrα Genes

(2016) Catarina Catela et al.   Cell Reports

Comment on "Hotair Is Dispensable for Mouse Development"

(2016) Lingjie Li et al.   PLoS Genetics

PEAT: an intelligent and efficient paired-end sequencing adapter trimming algorithm

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Systematic Discovery of Xist RNA Binding Proteins

(2015) Ci Chu et al.   CELL

Morphogen rules: design principles of gradient-mediated embryo patterning

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Comprehensive clinical studies in 34 patients with molecularly defined UPD(14)pat and related conditions (Kagami–Ogata syndrome)

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Kagami–Ogata syndrome: a clinically recognizable upd(14)pat and related disorder affecting the chromosome 14q32.2 imprinted region

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Toward a Consensus on the Binding Specificity and Promiscuity of PRC2 for RNA

(2015) Chen Davidovich et al.   MOLECULAR CELL

Mechanisms of Long Non-coding RNAs in Mammalian Nervous System Development, Plasticity, Disease, and Evolution

(2015) James A. Briggs et al.   NEURON

The recruitment of chromatin modifiers by long noncoding RNAs: lessons from PRC2

(2015) Chen Davidovich et al.   RNA

Loss of motoneuron-specific microRNA-218 causes systemic neuromuscular failure

(2015) N. D. Amin et al.   SCIENCE

CTCF establishes discrete functional chromatin domains at theHoxclusters during differentiation

(2015) Varun Narendra et al.   SCIENCE

Loss of non-coding RNA expression from the DLK1-DIO3 imprinted locus correlates with reduced neural differentiation potential in human embryonic stem cell lines

(2015) Chu-Fan Mo et al.   Stem Cell Research & Therapy

Mir-17∼92 Governs Motor Neuron Subtype Survival by Mediating Nuclear PTEN

(2015) Ying-Tsen Tung et al.   Cell Reports

PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells

(2015) Partha Pratim Das et al.   Cell Reports

Exploration of hydroxymethylation in Kagami-Ogata syndrome caused by hypermethylation of imprinting control regions

(2015) Keiko Matsubara et al.   Clinical Epigenetics

HTSeq--a Python framework to work with high-throughput sequencing data

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The miR-379/miR-410 cluster at the imprinted Dlk1-Dio3 domain controls neonatal metabolic adaptation

(2014) S. Labialle et al.   EMBO JOURNAL

Nascent RNA interaction keeps PRC2 activity poised and in check

(2014) Syuzo Kaneko et al.   GENES & DEVELOPMENT

Regulatory Interactions between RNA and Polycomb Repressive Complex 2

(2014) Catherine Cifuentes-Rojas et al.   MOLECULAR CELL

Jarid2 Is Implicated in the Initial Xist-Induced Targeting of PRC2 to the Inactive X Chromosome

(2014) Simão Teixeira da Rocha et al.   MOLECULAR CELL

Interactions between JARID2 and Noncoding RNAs Regulate PRC2 Recruitment to Chromatin

(2014) Syuzo Kaneko et al.   MOLECULAR CELL

RNA Binding of PRC2: Promiscuous or Well Ordered?

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Analysis of nuclear RNA interference in human cells by subcellular fractionation and Argonaute loading

(2014) Keith T Gagnon et al.   Nature Protocols

Polycomb Repressive Complex 2 Regulates Lineage Fidelity during Embryonic Stem Cell Differentiation

(2014) Seraphim R. Thornton et al.   PLoS One

Efficient in vivo deletion of a large imprinted lncRNA by CRISPR/Cas9

(2014) Jinxiong Han et al.   RNA Biology

Dlk1 Promotes a Fast Motor Neuron Biophysical Signature Required for Peak Force Execution

(2014) D. Muller et al.   SCIENCE

Long Noncoding RNAs: Past, Present, and Future

(2013) J. T. Y. Kung et al.   GENETICS

Occupying Chromatin: Polycomb Mechanisms for Getting to Genomic Targets, Stopping Transcriptional Traffic, and Staying Put

(2013) Jeffrey A. Simon et al.   MOLECULAR CELL

Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity

(2013) Esteban O Mazzoni et al.   NATURE NEUROSCIENCE

Saltatory remodeling of Hox chromatin in response to rostrocaudal patterning signals

(2013) Esteban O Mazzoni et al.   NATURE NEUROSCIENCE

Promiscuous RNA binding by Polycomb repressive complex 2

(2013) Chen Davidovich et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Transcriptional regulation by Polycomb group proteins

(2013) Luciano Di Croce et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Hox Genes: Choreographers in Neural Development, Architects of Circuit Organization

(2013) Polyxeni Philippidou et al.   NEURON

Long noncoding RNAs in development and disease of the central nervous system

(2013) Shi-Yan Ng et al.   TRENDS IN GENETICS

Long Noncoding RNAs in Development: Solidifying the Lncs to Hox Gene Regulation

(2013) Jeremy S. Dasen   Cell Reports

Targeted Disruption of Hotair Leads to Homeotic Transformation and Gene Derepression

(2013) Lingjie Li et al.   Cell Reports

Genetic and Functional Modularity of Hox Activities in the Specification of Limb-Innervating Motor Neurons

(2013) Julie Lacombe et al.   PLoS Genetics

Hdac6 regulates Tip60-p400 function in stem cells

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Genome Regulation by Long Noncoding RNAs

(2012) John L. Rinn et al.   Annual Review of Biochemistry

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(2012) Alexander Dobin et al.   BIOINFORMATICS

Polycomb repressive complex 1 activities determine the columnar organization of motor neurons

(2012) M. G. Golden et al.   GENES & DEVELOPMENT

GENCODE: The reference human genome annotation for The ENCODE Project

(2012) J. Harrow et al.   GENOME RESEARCH

Identification of imprinting regulators at the Meg3 differentially methylated region

(2012) Erin N. McMurray et al.   GENOMICS

Overexpression of the long non-coding RNA MEG3 impairs in vitro glioma cell proliferation

(2012) Pengjun Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

MEG3 noncoding RNA: a tumor suppressor

(2012) Yunli Zhou et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

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(2012) Ben Langmead et al.   NATURE METHODS

MAnorm: a robust model for quantitative comparison of ChIP-Seq data sets

(2012) Zhen Shao et al.   GENOME BIOLOGY

SnapShot: Spinal Cord Development

(2011) William A. Alaynick et al.   CELL

Mbd3/NURD Complex Regulates Expression of 5-Hydroxymethylcytosine Marked Genes in Embryonic Stem Cells

(2011) Ozlem Yildirim et al.   CELL

Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses

(2011) M. N. Cabili et al.   GENES & DEVELOPMENT

Genomic Maps of Long Noncoding RNA Occupancy Reveal Principles of RNA-Chromatin Interactions

(2011) Ci Chu et al.   MOLECULAR CELL

A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression

(2011) Kevin C. Wang et al.   NATURE

The Polycomb complex PRC2 and its mark in life

(2011) Raphaël Margueron et al.   NATURE

Embryonic stem cell–based mapping of developmental transcriptional programs

(2011) Esteban O Mazzoni et al.   NATURE METHODS

Non-coding RNAs in human disease

(2011) Manel Esteller   NATURE REVIEWS GENETICS

Non-coding RNAs as regulators of embryogenesis

(2011) Andrea Pauli et al.   NATURE REVIEWS GENETICS

Mir-17-3p Controls Spinal Neural Progenitor Patterning by Regulating Olig2/Irx3 Cross-Repressive Loop

(2011) Jun-An Chen et al.   NEURON

Mir-290-295 deficiency in mice results in partially penetrant embryonic lethality and germ cell defects

(2011) L. A. Medeiros et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ligand-dependent dynamics of retinoic acid receptor binding during early neurogenesis

(2011) Shaun Mahony et al.   GENOME BIOLOGY

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene

(2010) Y. Zhou et al.   DEVELOPMENT

Genome-wide Identification of Polycomb-Associated RNAs by RIP-seq

(2010) Jing Zhao et al.   MOLECULAR CELL

Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells

(2010) Matthias Stadtfeld et al.   NATURE

JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells

(2010) Diego Pasini et al.   NATURE

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

(2010) M.-C. Tsai et al.   SCIENCE

Inactive yet indispensable: the tale of Jarid2

(2010) David Landeira et al.   TRENDS IN CELL BIOLOGY

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

Jarid2/Jumonji Coordinates Control of PRC2 Enzymatic Activity and Target Gene Occupancy in Pluripotent Cells

(2009) Jamy C. Peng et al.   CELL

Maternally Expressed Gene 3 (MEG3) Noncoding Ribonucleic Acid: Isoform Structure, Expression, and Functions

(2009) Xun Zhang et al.   ENDOCRINOLOGY

Lessons from X-chromosome inactivation: long ncRNA as guides and tethers to the epigenome

(2009) J. T. Lee   GENES & DEVELOPMENT

Deletion of Gtl2 , imprinted non-coding RNA, with its differentially methylated region induces lethal parent-origin-dependent defects in mice

(2009) Nozomi Takahashi et al.   HUMAN MOLECULAR GENETICS

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

(2009) Ahmad M. Khalil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-206 Delays ALS Progression and Promotes Regeneration of Neuromuscular Synapses in Mice

(2009) A. H. Williams et al.   SCIENCE

The Genetic Signatures of Noncoding RNAs

(2009) John S. Mattick   PLoS Genetics

Hox Repertoires for Motor Neuron Diversity and Connectivity Gated by a Single Accessory Factor, FoxP1

(2008) Jeremy S. Dasen et al.   CELL

Genomic imprinting at the mammalian Dlk1-Dio3 domain

(2008) Simao Teixeira da Rocha et al.   TRENDS IN GENETICS