Journal
CURRENT DRUG DELIVERY
Volume 16, Issue 3, Pages 195-214Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1567201815666181031162208
Keywords
Graphene; graphene nanoplatelets; graphene nanoribbons; drug delivery; antimicrobial therapy; tissue engineering; graphene biocompatibility
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Graphene in nano form has proven to be one of the most remarkable materials. It has a single atom thick molecular structure and it possesses exceptional physical strength, electrical and electronic properties. Applications of the Graphene Family of Nanomaterials (GFNs) in different fields of therapy have emerged, including for targeted drug delivery in cancer, gene delivery, antimicrobial therapy, tissue engineering and more recently in more diseases including HIV. This review seeks to analyze current advances of potential applications of graphene and its family of nano-materials for drug delivery and other major biomedical purposes. Moreover, safety and toxicity are the major roadblocks preventing the use of GFNs in therapeutics. This review intends to analyze the safety and biocompatibility of GFNs along with the discussion on the latest techniques developed for toxicity reduction and biocompatibility enhancement of GFNs. This review seeks to evaluate how GFNs in future will serve as biocompatible and useful biomaterials in therapeutics.
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