- Home
- Publications
- Publication Search
- Publication Details
Title
Epigenetic therapy for ovarian cancer: promise and progress
Authors
Keywords
Ovarian cancer, Epigenetics, DNA methylation, Histone modifications, DNMT inhibitors, HDAC inhibitors
Journal
Clinical Epigenetics
Volume 11, Issue 1, Pages -
Publisher
Springer Nature
Online
2019-01-15
DOI
10.1186/s13148-018-0602-0
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Immune-Active Microenvironment in Small Cell Carcinoma of the Ovary, Hypercalcemic Type: Rationale for Immune Checkpoint Blockade
- (2018) Petar Jelinic et al. JNCI-Journal of the National Cancer Institute
- APR-246 reactivates mutant p53 by targeting cysteines 124 and 277
- (2018) Qiang Zhang et al. Cell Death & Disease
- Repurposing Pan-HDAC Inhibitors for ARID1A -Mutated Ovarian Cancer
- (2018) Takeshi Fukumoto et al. Cell Reports
- Immune-Active Microenvironment in Small Cell Carcinoma of the Ovary, Hypercalcemic Type: Rationale for Immune Checkpoint Blockade
- (2018) Petar Jelinic et al. JNCI-Journal of the National Cancer Institute
- A randomised, open-label, phase 2 study of the IDO1 inhibitor epacadostat (INCB024360) versus tamoxifen as therapy for biochemically recurrent (CA-125 relapse)–only epithelial ovarian cancer, primary peritoneal carcinoma, or fallopian tube cancer
- (2017) Rebecca Kristeleit et al. GYNECOLOGIC ONCOLOGY
- Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial
- (2017) Robert L Coleman et al. LANCET
- ARID1A-mutated ovarian cancers depend on HDAC6 activity
- (2017) Benjamin G. Bitler et al. NATURE CELL BIOLOGY
- Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden
- (2017) Meredith L. Stone et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Leveraging immunotherapy for the treatment of gynecologic cancers in the era of precision medicine
- (2016) Dmitriy Zamarin et al. GYNECOLOGIC ONCOLOGY
- Ovarian cancer and the immune system — The role of targeted therapies
- (2016) Taylor B. Turner et al. GYNECOLOGIC ONCOLOGY
- Targeting the cancer epigenome for therapy
- (2016) Peter A. Jones et al. NATURE REVIEWS GENETICS
- BET Bromodomain Inhibition as a Therapeutic Strategy in Ovarian Cancer by Downregulating FoxM1
- (2016) Zhenfeng Zhang et al. Theranostics
- Tumor infiltrating lymphocytes in ovarian cancer
- (2015) Phillip P Santoiemma et al. CANCER BIOLOGY & THERAPY
- DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts
- (2015) David Roulois et al. CELL
- Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses
- (2015) Katherine B. Chiappinelli et al. CELL
- Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers
- (2015) Benjamin G Bitler et al. NATURE MEDICINE
- Epigenetic treatment of solid tumours: a review of clinical trials
- (2015) Clara Nervi et al. Clinical Epigenetics
- Decitabine Enhances Lymphocyte Migration and Function and Synergizes with CTLA-4 Blockade in a Murine Ovarian Cancer Model
- (2015) L. Wang et al. Cancer Immunology Research
- A first in man phase I trial of the oral immunomodulator, indoximod, combined with docetaxel in patients with metastatic solid tumors
- (2015) Hatem H. Soliman et al. Oncotarget
- Intermediate clinical endpoints: A bridge between progression-free survival and overall survival in ovarian cancer trials
- (2014) Ursula A. Matulonis et al. CANCER
- Mutant p53 in Cancer: New Functions and Therapeutic Opportunities
- (2014) Patricia A.J. Muller et al. CANCER CELL
- p53 as a target for the treatment of cancer
- (2014) Michael J. Duffy et al. CANCER TREATMENT REVIEWS
- Targeting Tumor Suppressor p53 for Cancer Therapy: Strategies, Challenges and Opportunities
- (2014) Bo Hong et al. CURRENT DRUG TARGETS
- Catumaxomab for the Treatment of Malignant Ascites in Patients With Chemotherapy-Refractory Ovarian Cancer
- (2014) Jonathan S. Berek et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- Bevacizumab Combined With Chemotherapy for Platinum-Resistant Recurrent Ovarian Cancer: The AURELIA Open-Label Randomized Phase III Trial
- (2014) Eric Pujade-Lauraine et al. JOURNAL OF CLINICAL ONCOLOGY
- ZNF300P1 Encodes a lincRNA that regulates cell polarity and is epigenetically silenced in type II epithelial ovarian cancer
- (2014) Brian Gloss et al. Molecular Cancer
- The H3K9 methyltransferase G9a is a marker of aggressive ovarian cancer that promotes peritoneal metastasis
- (2014) Kuo-Tai Hua et al. Molecular Cancer
- The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints
- (2014) Nicolas J. Llosa et al. Cancer Discovery
- Epigenetic Potentiation of NY-ESO-1 Vaccine Therapy in Human Ovarian Cancer
- (2014) K. Odunsi et al. Cancer Immunology Research
- Epigenome-wide ovarian cancer analysis identifies a methylation profile differentiating clear-cell histology with epigenetic silencing of the HERG K+ channel
- (2013) Mine S. Cicek et al. HUMAN MOLECULAR GENETICS
- Methylation and histone deacetylase inhibition in combination with platinum treatment in patients with advanced malignancies
- (2013) Gerald S. Falchook et al. INVESTIGATIONAL NEW DRUGS
- Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer
- (2013) Hui Shen et al. Nature Communications
- Epigenetic Resensitization to Platinum in Ovarian Cancer
- (2012) D. Matei et al. CANCER RESEARCH
- Association Between BRCA1 and BRCA2 Mutations and Survival in Women With Invasive Epithelial Ovarian Cancer
- (2012) Kelly L. Bolton JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- MDM2 inhibition in liposarcoma: a step in the right direction
- (2012) Anastasia Constantinidou et al. LANCET ONCOLOGY
- Effect of the MDM2 antagonist RG7112 on the P53 pathway in patients with MDM2-amplified, well-differentiated or dedifferentiated liposarcoma: an exploratory proof-of-mechanism study
- (2012) Isabelle Ray-Coquard et al. LANCET ONCOLOGY
- Chromatin H3K27me3/H3K4me3 histone marks define gene sets in high-grade serous ovarian cancer that distinguish malignant, tumour-sustaining and chemo-resistant ovarian tumour cells
- (2012) N Chapman-Rothe et al. ONCOGENE
- Correction: VENNTURE–A Novel Venn Diagram Investigational Tool for Multiple Pharmacological Dataset Analysis
- (2012) Bronwen Martin et al. PLoS One
- Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)
- (2012) M. T. McCabe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Recent progress in the diagnosis and treatment of ovarian cancer
- (2011) Danijela Jelovac et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Prognostic significance of tumor-infiltrating T cells in ovarian cancer: A meta-analysis
- (2011) Wei-Ting Hwang et al. GYNECOLOGIC ONCOLOGY
- Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing
- (2011) T. Walsh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Combination Epigenetic Therapy Has Efficacy in Patients with Refractory Advanced Non-Small Cell Lung Cancer
- (2011) R. A. Juergens et al. Cancer Discovery
- Phase 1b-2a study to reverse platinum resistance through use of a hypomethylating agent, azacitidine, in patients with platinum-resistant or platinum-refractory epithelial ovarian cancer
- (2010) Siqing Fu et al. CANCER
- ARID1AMutations in Endometriosis-Associated Ovarian Carcinomas
- (2010) Kimberly C. Wiegand et al. NEW ENGLAND JOURNAL OF MEDICINE
- Systematic Review and Meta-analysis of Ovarian Cancers: Estimation of Microsatellite-High Frequency and Characterization of Mismatch Repair Deficient Tumor Histology
- (2008) T. Pal et al. CLINICAL CANCER RESEARCH
- Phase II trial of cetuximab and carboplatin in relapsed platinum-sensitive ovarian cancer and evaluation of epidermal growth factor receptor expression: A Gynecologic Oncology Group study
- (2008) Angeles Alvarez Secord et al. GYNECOLOGIC ONCOLOGY
- Low-grade serous ovarian cancer: a unique disease
- (2008) Kathleen M. Schmeler et al. Current Oncology Reports
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search