Role of the Death Receptor and Endoplasmic Reticulum Stress Signaling Pathways in Polyphyllin I-Regulated Apoptosis of Human Hepatocellular Carcinoma HepG2 Cells

Impact of Facility Type and Surgical Volume on 10-Year Survival in Patients Undergoing Hepatic Resection for Hepatocellular Carcinoma

(2017) Brandon C. Chapman et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Hepatocellular carcinoma review: Current treatment, and evidence-based medicine

(2017) Bulent Karaman et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis

(2016) Bin Zhang et al.   BIOCHEMICAL PHARMACOLOGY

Polyphyllin I induces cell cycle arrest and apoptosis in human myeloma cells via modulatingβ-catenin signaling pathway

(2016) Yun Liang et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Inhibition of EZH2 via activation of SAPK/JNK and reduction of p65 and DNMT1 as a novel mechanism in inhibition of human lung cancer cells by polyphyllin I

(2016) Longmei Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Saponins from Chinese Medicines as Anticancer Agents

(2016) Xiao-Huang Xu et al.   MOLECULES

Hepatitis B virus core protein inhibits Fas-mediated apoptosis of hepatoma cells via regulation of mFas/FasL and sFas expression

(2015) Wei Liu et al.   FASEB JOURNAL

Downregulation of E2F1 during ER stress is required to induce apoptosis

(2015) V. Pagliarini et al.   JOURNAL OF CELL SCIENCE

The Association Between p38 MAPK-Mediated TNF-α/TNFR2 up-Regulation and 2-(4-Aminophenyl)-7-Methoxybenzothiazole-Induced Apoptosis in Human Leukemia U937 Cells

(2015) Chia-Hui Huang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Molecular mechanisms of Polyphyllin I-induced apoptosis and reversal of the epithelial–mesenchymal transition in human osteosarcoma cells

(2015) Junli Chang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Huachansu suppresses human bladder cancer cell growth through the Fas/Fasl and TNF- alpha/TNFR1 pathway in vitro and in vivo

(2015) Tao Yang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Polyphyllin I induced-apoptosis is enhanced by inhibition of autophagy in human hepatocellular carcinoma cells

(2015) Ya-Min Shi et al.   PHYTOMEDICINE

ER stress-induced cell death mechanisms

(2013) Renata Sano et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Death receptors as targets in cancer

(2013) O Micheau et al.   BRITISH JOURNAL OF PHARMACOLOGY

Pharmacological targeting of endoplasmic reticulum stress signaling in cancer

(2012) Axel H. Schönthal   BIOCHEMICAL PHARMACOLOGY

dsRNA induces apoptosis through an atypical death complex associating TLR3 to caspase-8

(2012) Y Estornes et al.   CELL DEATH AND DIFFERENTIATION

Solanum lyratumExtracts Induce Extrinsic and Intrinsic Pathways of Apoptosis in WEHI-3 Murine Leukemia Cells and Inhibit Allograft Tumor

(2012) Jai-Sing Yang et al.   Evidence-based Complementary and Alternative Medicine

Endoplasmic reticulum stress contributes to arsenic trioxide-induced apoptosis in drug-sensitive and -resistant leukemia cells

(2012) Jing Chen et al.   LEUKEMIA RESEARCH

RNA surveillance is required for endoplasmic reticulum homeostasis

(2012) K. Sakaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unfolded protein response in cancer: the Physician's perspective

(2011) Xuemei Li et al.   Journal of Hematology & Oncology

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Outcome after curative resection for a huge (≥10 cm) hepatocellular carcinoma and prognostic significance of gross tumor classification

(2009) Gi Hong Choi et al.   AMERICAN JOURNAL OF SURGERY

Caspase-independent cell death: leaving the set without the final cut

(2008) S W G Tait et al.   ONCOGENE

Proteomic and transcriptomic study on the action of a cytotoxic saponin (Polyphyllin D): Induction of endoplasmic reticulum stress and mitochondria-mediated apoptotic pathways

(2008) Fung-Ming Siu et al.   PROTEOMICS

Polyphyllin D induces mitochondrial fragmentation and acts directly on the mitochondria to induce apoptosis in drug-resistant HepG2 cells

(2007) Rose C.Y. Ong et al.   CANCER LETTERS