Journal
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
Volume 7, Issue 2, Pages 1875-1878Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acssuschemeng.8b06096
Keywords
Iodooxygenation; Isoxazolines; Water; Atom economy; Green synthesis
Categories
Funding
- National Key Research and Development Program of China [2017YFC0210900]
- Innovative Experimental Project of Zhejiang University of Technology [SYXM1704]
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An efficient intramolecular iodooxygenation of unsaturated ketoximes has been achieved through the activation of iodine by TBHP, yielding various types of synthetically versatile iodinated isoxazolines. This potentially general method is featured by its high atom economy, significant organic waste reduction, and mild reaction conditions.
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