Article
Environmental Sciences
Reka Svigruha, Istvan Fodor, Janos Gyori, Janos Schmidt, Judit Padisak, Zsolt Pirger
Summary: This study investigated the effects of progestogens in mixtures at environmentally relevant concentrations on Daphnia magna for the first time, finding significant impacts on molecular, cellular, and individual levels in both short-term and long-term exposures, including increased gene expression and activity of GST detoxification enzyme, as well as changes in reproductive capacity. Future research should focus on understanding the potential mechanisms underlying these effects.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Engineering, Environmental
Young Hwan Lee, Min-Sub Kim, Yoseop Lee, Chuxin Wang, Seong Chan Yun, Jae-Seong Lee
Summary: This study investigated the effects of interactions between microfibers and freshwater acidification (MFA) on individual Daphnia magna-microbiota interactions. The results showed that MFA interactions can have negative consequences on reproduction, growth, and sex ratio of D. magna, and can induce changes in immunity-and reproduction-related biological processes. The study also revealed that these adverse effects are closely related to changes in microbial communities, suggesting a causal link between D. magna fitness and the microbial community.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Marine & Freshwater Biology
Haksoo Jeong, Young Hwan Lee, Alaa El -Din H. Sayed, Chang-Bum Jeong, Bingsheng Zhou, Jae-Seong Lee, Eunjin Byeon
Summary: This study investigated the effects of microplastics and chromium on the freshwater organism Daphnia magna. The results showed significant deleterious effects and acute toxicity in Daphnia magna exposed to microplastics, chromium, and their combination. Oxidative stress alterations were observed, and the interaction between microplastics and chromium was indicated. In addition, microplastic exposure led to changes in enzyme activities and mitochondrial transcription dysfunction induced by chromium.
AQUATIC TOXICOLOGY
(2022)
Article
Marine & Freshwater Biology
Petar G. Davidovic, Dajana J. Blagojevic, Gospava G. Lazic, Jelica B. Simeunovic
Summary: This study investigated the toxicity effects of two strains of Nostoc cyanobacteria on Daphnia magna. The study found that while there were minor changes in survival rates, significant molecular responses were observed. Both strains of cyanobacteria caused increases in the expression of glutathione S-transferase (gst) and vitellogenin (vtg). Low concentrations of microcystins suggest that they were not responsible for the observed toxic effects.
Article
Microbiology
Kathrine Obrestad, Sigurd Einum, Olav Vadstein
Summary: Stochastic processes impact gut bacterial composition, which alters the reproductive rate of Daphnia magna.
FEMS MICROBIOLOGY ECOLOGY
(2022)
Article
Marine & Freshwater Biology
Haksoo Jeong, Cheolho Yoon, Jae-Seong Lee, Eunjin Byeon
Summary: To examine the role of GST-O2 genes in biotransformation and detoxification in Daphnia magna, the study investigated various responses such as in vivo endpoints, arsenic speciation, enzymatic activities, and gene expression pathways. The results showed that MT fleas had higher sensitivity to arsenic and a lower rate of arsenate reduction, leading to higher accumulation of arsenic concentrations and decreased protection against toxicity. The mRNA expression of other GST genes increased but the enzymatic activity of GST decreased in the MT group compared to the WT group. The study highlights the important role of GST-O2 in arsenic biotransformation and detoxification in D. magna.
AQUATIC TOXICOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Maria Jos Mantas, Peter B. Nunn, Geoffrey A. Codd, Daniel Barker
Summary: Cyanobacteria are a type of ancient clade of photosynthetic prokaryotes found in various habitats worldwide, including water resources. They may pose health hazards due to the production of cyanotoxins, including the neurotoxin BMAA. The biosynthetic pathways for BMAA in cyanobacteria are not well understood, with potential connections to iron-scavenging and unclear taxonomic distribution.
Article
Fisheries
Gulsah Turcihan, Melek Isinibilir Okyar, Yusuf Gufran Zeybek, Kamil Mert Eryalcin
Summary: This research evaluated the effects of different diets on the growth and survival of Daphnia magna. The results showed that feeding the water flea with baker's yeast increased its reproduction and population density, while feeding it with Nannochloropsis oculata increased protein levels. The Daphnia fed with Botrycoccus braunii had the highest lipid and EPA content.
AQUACULTURE RESEARCH
(2022)
Article
Zoology
Kenji Toyota, Masaki Yasugi, Norihisa Tatarazako, Taisen Iguchi, Eiji Watanabe
Summary: In this study, the swimming patterns and dynamics of male and female D. magna were analyzed using computer modeling. The results showed that males displayed greater diffusion in the horizontal direction, which could increase the probability of encountering distant mates. These findings reveal the sex-specific characteristics and reproductive strategies of D. magna.
JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-ECOLOGICAL AND INTEGRATIVE PHYSIOLOGY
(2022)
Article
Toxicology
Megumi Matsumoto, Haruka Ito, Ayaka Tateishi, Yasuaki Kobayashi, Kotaro Satoh, Keiji Numata, Hitoshi Miyakawa
Summary: Plastics have brought many benefits to our lives, but their persistence in the environment causes serious problems. Research on biodegradable plastics and polymer toxicity assessment often focuses on standardized substances and neglects changes in toxicity due to degradation products. Understanding the impact of degraded polymers on biological activities is crucial for accurate risk assessment.
JOURNAL OF APPLIED TOXICOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Duck-Hyun Kim, Young Hwan Lee, Alaa El-Din H. Sayed, Ik-Young Choi, Jae-Seong Lee
Summary: This study identified GPCR genes in the water flea Daphnia magna to better understand GPCR signaling and its relationship with crustacean endocrinology. The findings suggest shared evolutionary tendencies among different GPCR gene classes and highlight the conservation of certain GPCRs across species.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS
(2022)
Article
Environmental Sciences
Sevgi Basalan Over, Celal Guven, Eylem Taskin, Arif Cakmak, Petek Piner Benli, Yusuf Sevgiler
Summary: The study found that ammonia and TBM induced acute and chronic toxicity effects on D. magna, leading to an energy crisis in the organism. Traditional biomarkers like GST and ChE were not sensitive in detecting these effects, while AMPK and MMP show promise as biomarkers for these toxicants.
ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
(2021)
Article
Environmental Sciences
Mengting Li, Vera Slaveykova
Summary: This study investigated the influence of titanium dioxide nanoparticles (nTiO(2)) on the accumulation and transfer of inorganic and monomethyl mercury in invertebrate Daphnia magna. The results showed that nTiO(2) led to a decrease in total mercury body burden in D. magna exposed through waterborne exposure, but an increase when exposed through nTiO(2) pre-treated with mercury. The presence of nTiO(2) also decreased the total mercury in D. magna when exposed through algal food. Additionally, high concentrations of nTiO(2) favored trophic transfer of mercury through feeding on nTiO(2) pre-treated with mercury. The results provide insights into the role of nTiO(2) in the bioavailability and trophic transfer of mercury in the aquatic environment.
ENVIRONMENTAL POLLUTION
(2022)
Article
Environmental Sciences
Jin-Sol Lee, Yunmoon Oh, Jae-Seong Lee, Hyung Sik Kim
Summary: In this study, the acute toxicity of triclosan (TCS) in Daphnia magna was measured. The results showed that TCS induced oxidative stress and damage to apoptotic proteins in D. magna. The study also investigated the multi- and transgenerational effects of TCS on D. magna, revealing negative impacts on antioxidant responses, DNA fragmentation, and reproductive rates.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Marine & Freshwater Biology
Eunjin Byeon, Min-Sub Kim, Duck-Hyun Kim, Yoseop Lee, Haksoo Jeong, Jin-Sol Lee, Sung-Ah Hong, Jun Chul Park, Hye-Min Kang, Alaa El-Din H. Sayed, Yasuhiko Kato, Sangsu Bae, Hajime Watanabe, Young Hwan Lee, Jae-Seong Lee
Summary: In this study, the genome of the water flea Daphnia magna NIES strain was assembled using Oxford nanopore sequencing tool, and gene targeting was successfully demonstrated using CRISPR/Cas9 technology with the glutathione S-transferase omega 2 (GST-O2) gene as an example. Mutant lines were efficiently created and compared to wild type for their response to arsenic exposure. This research contributes to the future construction of deletion mutants in D. magna for further study of gene functions related to pollutant resistance.
AQUATIC TOXICOLOGY
(2022)
Article
Biology
Peter Klepsatel, Thirnahalli Nagaraj Girish, Heinrich Dircksen, Martina Galikova
JOURNAL OF EXPERIMENTAL BIOLOGY
(2019)
Article
Cell Biology
Marta A. Polanska, Tina Kirchhoff, Heinrich Dircksen, Bill S. Hansson, Steffen Harzsch
CELL AND TISSUE RESEARCH
(2020)
Article
Evolutionary Biology
Peter Klepsatel, Diana Knoblochova, Thirnahalli Nagaraj Girish, Heinrich Dircksen, Martina Galikova
BMC EVOLUTIONARY BIOLOGY
(2020)
Article
Multidisciplinary Sciences
Peter Klepsatel, Thirnahalli Nagaraj Girish, Martina Galikov
SCIENTIFIC REPORTS
(2020)
Editorial Material
Endocrinology & Metabolism
Haihui Ye, Marcy N. Wilder, Heinrich Dircksen, J. Sook Chung
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Neurosciences
Steffen Harzsch, Heinrich Dircksen, Bill S. Hansson
Summary: The study reveals a higher level of structural complexity in the crustacean olfactory glomeruli compared to insects, with peptidergic and aminergic interneurons playing a central role in information transfer. Additionally, unknown neuronal elements mediating lateral inhibitory interactions modulate sensory input to output neurons.
JOURNAL OF COMPARATIVE NEUROLOGY
(2022)
Article
Biology
Peter Klepsatel, Martina Galikova
Summary: Animals in their natural environments need to adapt to fluctuations in various factors, and phenotypic plasticity can help them survive under changing conditions. A study on fruit flies found that developmental temperature affects the thermal performance curve for locomotor activity, influencing factors such as maximum performance, thermal optimum, and performance breadth. However, it did not consistently affect circadian rhythms. This sensitivity to developmental conditions may be important for the fitness of fruit flies in changing environments.
JOURNAL OF THERMAL BIOLOGY
(2022)
Review
Cell Biology
Martina Galikova, Peter Klepsatel
Summary: Over the past decade, the combination of genetic, transcriptomic, and proteomic approaches has provided valuable insights into the mechanisms of energy storage and breakdown in model organisms. The fruit fly Drosophila melanogaster has been particularly useful in understanding the genetic regulation of energy metabolism. Despite evolutionary differences, the energy storage organs, metabolic pathways, and genetic regulations are relatively conserved. However, there are significant variations in the factors and pathways involved in energy mobilization during different developmental stages and contexts, even within a single insect species.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Philip Suess, Heinrich Dircksen, Kevin T. Roberts, Karl Gotthard, Dick R. Nassel, Christopher W. Wheat, Mikael A. Carlsson, Philipp Lehmann
Summary: Diapause is a crucial mechanism for insects to adapt their life cycle to adverse conditions, with key regulators being ecdysone and PTTH. Termination of diapause under low temperatures may occur precociously.
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2022)
Editorial Material
Physiology
Haihui Ye, Chaoshu Zeng, Naoaki Tsutsui, Heinrich Dircksen
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Neurosciences
Uwe Homberg, Ronja Hensgen, Evelyn Rieber, Jutta Seyfarth, Martina Kern, Stefan Dippel, Heinrich Dircksen, Lisa Spaenig, Yelda Pakize Kina
Summary: The central complex is a highly interconnected group of neuropils in the insect brain, involved in controlling spatial orientation. Studies on the desert locust have shown that neuropeptides, particularly orcokinin, play a significant role in neural signaling within this brain region. In addition, in silico transcript analysis identified eight different orcokinin-A type peptides in the desert locust, suggesting their involvement in signal processing in the central complex.
JOURNAL OF COMPARATIVE NEUROLOGY
(2021)
Article
Neurosciences
Jodi L. Alexander, Andrew Oliphant, David C. Wilcockson, Timothy Brendler-Spaeth, Heinrich Dircksen, Simon G. Webster
FRONTIERS IN NEUROSCIENCE
(2020)
Article
Multidisciplinary Sciences
Peter Klepsatel, David Wildridge, Martina Galikova
SCIENTIFIC REPORTS
(2019)