Article
Chemistry, Multidisciplinary
Abdul Khayum Mohammed, Pilar Pena-Sanchez, Ajmal Pandikassala, Safa Gaber, Ayesha A. AlKhoori, Tina Skorjanc, Kyriaki Polychronopoulou, Sreekumar Kurungot, Felipe Gandara, Dinesh Shetty
Summary: A new class of copper-based 2D-c-MOF was synthesized using green mechano-chemistry, with metal coordination involving salicylaldehyde functional moiety explored for the first time in MOFs. Furthermore, a semiconductive copper-based SA-MOF thin film was successfully fabricated at room temperature using an in situ salt-free method.
CHEMICAL COMMUNICATIONS
(2023)
Article
Biochemistry & Molecular Biology
Ao-Hong Hu, Qi-Xuan Duan, Xin-Yuan Xiong, Zhuo Kang, Ai -Min Bai, Miao-Miao Yin, Yan-Jun Hu
Summary: GSH-AgNCs and DHLA-AgNCs were synthesized and their interactions with ctDNA were studied. GSH-AgNCs mainly bound to ctDNA in a groove mode, while DHLA-AgNCs were both groove and intercalation binding. The binding strength of DHLA-AgNCs to ctDNA was stronger than that of GSH-AgNCs. This study provides theoretical foundations and guidance for the biosafety and application of AgNCs.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Analytical
Guofang Zeng, Fengping Chen, Yating Lei, Like Zhou, Xi Yang, Hui Guo, Xun Tuo, Ying Guo
Summary: In this study, the binding properties between resorcinol and ct-DNA were investigated for the first time using various spectral and molecular docking techniques. The results showed that electrostatic force was the major driving force for the binding, with a binding constant of 1.56 x 10(4) M-1. The study also explicitly established the electrostatic binding network between resorcinol and ct-DNA, and found that resorcinol bound to the phosphate skeleton of DNA.
Article
Biochemistry & Molecular Biology
Saniyya Khan, Rizwan Ahmad, Imrana Naseem
Summary: In this study, the binding mechanics of aminophylline with calf thymus DNA were investigated, revealing that aminophylline binds to DNA in a minor groove binding mode. Various experiments and molecular docking studies were conducted to calculate the binding constant and binding energy, confirming the minor groove binding mode of aminophylline with DNA.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2021)
Article
Chemistry, Physical
Wioleta Bialobrzeska, Maciej J. Glowacki, Monika Janik, Mateusz Ficek, Krzysztof Pyrchla, Miroslaw Sawczak, Robert Bogdanowicz, Natalia Malinowska, Sabina Zoledowska, Dawid Nidzworski
Summary: OTA interacts with ct DNA on the nanodiamond surface, and the binding mechanism was elucidated using multispectroscopic techniques. The study showed that OTA can form complexes with ct DNA and interact in a groove-binding mode, providing new insights into the toxicological effect of mycotoxins.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Physical
Santanu Majumdar, Madhuri Ghosh, Suprabhat Mukherjee, Biswarup Satpati, Biswajit Dey
Summary: The formation of a flexible supramolecular hydrogel structure based on DNA and graphene oxide nanosheets leads to the achievement of nano-bio functionality. This hydrogel is utilized for the synthesis of functional silver nanoparticles and the production of smart bacteria-mediated nano-bio composites. Gram-positive and Gram-negative bacteria are employed to offer stability and catalytic effects on the silver nanoparticles.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Physical
Farnaz Ahmadi Oskooei, Jamshid Mehrzad, Ahmad Asoodeh, Alireza Motavalizadehkakhky
Summary: This study aimed to improve the solubility and stability of Quercetin's nanoemulsions and investigate its interaction properties with DNA. The results showed that Quercetin nanoemulsions exhibited cytotoxicity against cancer cells and demonstrated high antioxidant activity. The findings suggest the potential of Quercetin nanoemulsions as an effective delivery system for inducing apoptotic effects through interaction with DNA molecules.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Biochemistry & Molecular Biology
Fulya Kipcak, Tugba Taskin Tok, Halil Duyar, Zeynel Seferoglu, Elmas Gokoglu
Summary: The new CMR compound showed static binding to DNA and HSA with hydrophobic interaction playing a predominant role. Competition assays revealed CMR primarily binds in the A-T region of DNA's minor groove.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2021)
Article
Chemistry, Physical
Ayca Urcuk, Dilek Eskikoy Bayraktepe, Ceren Yildiz, Zehra Yazan
Summary: This work investigates the interaction between double-stranded calf thymus DNA (dsDNA) and the food additive vanillin through voltammetry. The study reveals the binding of vanillin to DNA through intercalation and electrostatic attraction.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Spectroscopy
Prasenjit Mondal, Priti Sengupta, Uttam Pal, Sutapa Saha, Adity Bose
Summary: This study investigated the binding interaction between sinapic acid and DNA, revealing that SA may bind to the groove position of DNA. In addition, gel electrophoresis analysis confirmed the protective efficacy of SA against UVB-induced DNA damage.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Physical
Song-Bo Kou, Kai-Li Zhou, Zhen-Yi Lin, Yan-Yue Lou, Jie-Hua Shi, Ying-Xin Liu
Summary: In this study, the molecular interaction mechanism between Lopinavir (LPV) and calf thymus deoxyribonucleic acid (ct-DNA) was characterized using spectroscopic, viscosity, and molecular docking approaches. The results showed that LPV bound to the minor groove of ct-DNA through hydrogen bonding and Van der Waals forces. This study provides insight into the binding behavior between LPV and ct-DNA, which can be beneficial for evaluating the pharmacological properties of this antiviral drug.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Physical
Abhijit Mukherjee, Suvranil Ghosh, Sudipta Ghosh, Sachinta Mahato, Mahadeb Pal, Sukanta Kumar Sen, Adinath Majee, Bula Singh
Summary: The synthesized halogenated chalcones (1f, 1h, 1i) demonstrate anti-cancer and antimicrobial activities, with the ability to interact with calf thymus DNA. These compounds actively bind to DNA through groove binding mode, inducing cancer cell death and showing antibacterial properties against model pathogenic bacteria.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Biochemistry & Molecular Biology
Hitesh Sehrawat, Neeraj Kumar, Sagar Panchal, Loveneesh Kumar, Ramesh Chandra
Summary: In this study, the interaction between opium poppy alkaloid noscapine-based ionic liquid [Pip-Nos]OTf and ct-DNA was investigated using various experimental and computational methods. The results suggest a groove binding mode of interaction between [Pip-Nos]OTf and ct-DNA, and highlight the potential role of [Pip-Nos]OTf in cancer therapeutics.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Nanoscience & Nanotechnology
Peng Lei, Ying Zhou, Bei Li, Yang Liu, Chuan Dong, Shaomin Shuang
Summary: A reliable and accurate electrochemical sensor based on a gold/palladium-polypyrrole/graphene nanocomposite has been developed for the detection of DNA bases. The sensor exhibits excellent electrocatalytic activity and a wide linear range, and can selectively identify the four bases in calf thymus DNA.
ACS APPLIED NANO MATERIALS
(2022)
Article
Chemistry, Physical
Lihong Jin, Peiyao Li, Jingyi Li, Huiru Yang, Xinglong Pan, Haiyan Li, Bingjun Shen
Summary: The study found that cinnamic acid can form a supramolecular system with DNA, quench the fluorescence of the DNA system, and increase the DNA's melting point. Further experiments showed that the structure of cinnamic acid molecule inserts between DNA base pairs, contributing to a better understanding of their interaction mechanism.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Multidisciplinary
C. Rey, N. Hengl, S. Baup, M. Karrouch, E. Gicquel, A. Dufresne, H. Djeridi, R. Dattani, Y. Jin, F. Pignon
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2019)
Article
Chemistry, Physical
Enrico F. Semeraro, Nicolas Hengl, Mohamed Karrouch, Laurent J. Michot, Erwan Paineau, Bruno Jean, Jean-Luc Putaux, Christine Lancelon-Pin, Lewis Sharpnack, Frederic Pignon
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2020)
Article
Physics, Multidisciplinary
Thomas Gibaud, Noemie Dages, Pierre Lidon, Guillaume Jung, L. Christian Ahoure, Michael Sztucki, Arnaud Poulesquen, Nicolas Hengl, Frederic Pignon, Sebastien Manneville
Article
Polymer Science
Christian Enrique Garcia Garcia, Felix Armando Soltero Martinez, Frederic Bossard, Marguerite Rinaudo
Article
Chemistry, Applied
Frederic Pignon, Mathilde Challamel, Antoine De Geyer, Mohamad Elchamaa, Enrico F. Semeraro, Nicolas Hengl, Bruno Jean, Jean-Luc Putaux, Erwan Gicquel, Julien Bras, Sylvain Prevost, Michael Sztucki, Theyencheri Narayanan, Henda Djeridi
Summary: The study investigated the breakdown and buildup mechanisms in concentrated cellulose nanocrystal suspensions under shear and during relaxation upon cessation of shear using small-angle X-ray and light scattering combined with rheometry. It observed dynamic structural changes over nanometer to micrometer lengthscales that were related to the well-known three-regime rheological behavior. The results showed that the suspension exhibited complex and dynamic changes in liquid crystal structures at different length scales in different rheological regimes.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Applied
Sarah da Costa Amaral, Denis Roux, Francois Caton, Marguerite Rinaudo, Shayla Fernanda Barbieri, Joana Lea Meira Silveira
Summary: The study investigated the extraction, purification, and isolation of pectin from Araca fruit pulp, revealing the composition of long galactumnic acid blocks and RG-I blocks with side chains containing mainly arabinose and galactose. Different treatment conditions did not affect the stability of the main chains, resulting in the formation of a stable physical gel.
FOOD HYDROCOLLOIDS
(2021)
Article
Biochemistry & Molecular Biology
B. Velasco-Rodriguez, T. Diaz-Vidal, L. C. Rosales-Rivera, C. A. Garcia-Gonzalez, C. Alvarez-Lorenzo, A. Al-Modlej, V. Dominguez-Arca, G. Prieto, S. Barbosa, J. F. A. Soltero Martinez, P. Taboada
Summary: The combination of methacroyl-modified HA and Gel in hybrid hydrogels result in improved mechanical properties and a stronger structure. The presence of HAMA leads to stiffer, less porous hydrogels that are more resistant to collagenase degradation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Physical
Frederic Pignon, Enrico F. Semeraro, William Chevremont, Hugues Bodiguel, Nicolas Hengl, Mohamed Karrouch, Michael Sztucki
Summary: The combined effect of shear flow and ultrasound waves can control the orientation of cellulosic cholesteric liquid crystals. By adjusting the intensity of shear flow and ultrasound, the orientation of CNCs can be tuned at a nanometer scale. Transient orientation of CNCs at an intermediate angle between horizontal and vertical directions was observed under specific shear rate to acoustic power ratios.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Chemistry, Multidisciplinary
Giuseppe Cavallaro, Giuseppe Lazzara, Frederic Pignon, Leonardo Chiappisi, Erwan Paineau
Summary: This study investigates the adsorption mechanism of nonionic polymers onto aluminogermanate imogolite nanotubes using nanoisothermal titration calorimetry. The results show that the affinity towards the nanotube surface is driven by enthalpy and strongly influenced by the polymer chain length. Small-angle neutron scattering and rheology techniques were used to probe the polymer configuration and flow properties of the complexes, providing insights for advanced applications.
Article
Multidisciplinary Sciences
Guillaume Maitrejean, Adeline Samson, Denis C. D. Roux
Summary: The present dataset provides the interfaces data of Newtonian fluid jets in Continuous InkJet (CIJ) printing process, allowing exploration of jet morphologies evolution. With the use of open-source Computational Fluid Dynamics software, a large number of jets were computed, enabling the application of machine learning and deep-learning methods for research purposes.
Article
Polymer Science
Denis C. D. Roux, Isabelle Jeacomine, Guillaume Maitrejean, Francois Caton, Marguerite Rinaudo
Summary: Agarose is a substance that forms a homogeneous thermoreversible gel in water, and the solid-liquid phase transitions are thermoreversible depending on the molecular structure of agarose. This study characterized the behavior of agarose gels in non-solvents and compared it to gels formed in water.
Article
Engineering, Chemical
Songlin Wen, Jun Huang, Rongqing Zhou, Chongde Wu, Nicolas Hengl, Frederic Pignon, Yao Jin
Summary: In this study, the filtration property of casein-chitosan complexes under different conditions was analyzed, and the fouling mechanism was explained. Results showed that a higher pH and more polysaccharide content can slow down fouling growth rate, but a higher pH is unfavorable for long-term processing. The effect of pH on the process was found to be more significant than other factors.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Chemistry, Physical
Alberto Varela-Feijoo, Philippe Djemia, Tetsuharu Narita, Frederic Pignon, Armelle Baeza-Squiban, Valentina Sirri, Alain Ponton
Summary: To study the mechanical properties of sodium alginate aqueous solutions at different scales, the researchers used macroscopic shear rheology, diffusing-wave spectroscopy microrheology, and Brillouin spectroscopy. They also examined the structural properties using small-angle X-ray scattering. The results showed a transition from polyelectrolyte behavior to neutral polymer behavior as the polymer concentration increased. The viscoelastic properties probed at high frequencies reflected changes in microscopic viscosity. In addition, the solutions demonstrated biocompatibility and potential biomedical applications.
Article
Chemistry, Physical
Lorenzo Metilli, Heloise Ugo, William Chevremont, Cyril Picard, Frederic Pignon
Summary: Metal-organic-frameworks (MOFs) are promising materials for addressing critical issues, but their limited processability hampers their large-scale deployment. The hybridization of MOFs with biopolymers has emerged as a greener, biocompatible strategy to shape MOFs into more processable materials. In this study, cellulose nanocrystals (CNCs) were used in combination with ZIF-8 to produce hybrid composites through ultrafiltration. Results showed that small quantities of CNCs were sufficient to form a self-supported, dense deposit with high ZIF-8 loadings. This approach allowed the tuning of the composition of the final nanocomposite by controlling the nature and quantities of particles in the suspension.
Article
Multidisciplinary Sciences
Ruxandra Cojocaru, Oonagh Mannix, Marie Capron, C. Giles Miller, Pierre-Henri Jounea, Benoit Gallet, Denis Falconet, Alexandra Pacureanu, Stephen Stukins
Summary: The study reveals the structure and properties of the pollen wall, providing a deeper understanding of the evolutionary success of conifers and other plants over geological time.