Downregulation of ERG and FLI1 expression in endothelial cells triggers endothelial-to-mesenchymal transition

Fli1 Deficiency Induces CXCL6 Expression in Dermal Fibroblasts and Endothelial Cells, Contributing to the Development of Fibrosis and Vasculopathy in Systemic Sclerosis

(2017) Takashi Taniguchi et al.   JOURNAL OF RHEUMATOLOGY

Dynamically and epigenetically coordinated GATA/ETS/SOX transcription factor expression is indispensable for endothelial cell differentiation

(2017) Yasuharu Kanki et al.   NUCLEIC ACIDS RESEARCH

mirDIP 4.1—integrative database of human microRNA target predictions

(2017) Tomas Tokar et al.   NUCLEIC ACIDS RESEARCH

Dynamic regulation of canonical TGFβ signalling by endothelial transcription factor ERG protects from liver fibrogenesis

(2017) Neil P. Dufton et al.   Nature Communications

EMT: 2016

(2016) M. Angela Nieto et al.   CELL

A potential contribution of altered cathepsin L expression to the development of dermal fibrosis and vasculopathy in systemic sclerosis

(2016) Takashi Yamashita et al.   EXPERIMENTAL DERMATOLOGY

deepTools2: a next generation web server for deep-sequencing data analysis

(2016) Fidel Ramírez et al.   NUCLEIC ACIDS RESEARCH

Endothelial to Mesenchymal Transition (EndoMT) in the Pathogenesis of Human Fibrotic Diseases

(2016) Sonsoles Piera-Velazquez et al.   Journal of Clinical Medicine

Activated Phosphatidylinositol 3-Kinase/Akt Inhibits the Transition of Endothelial Progenitor Cells to Mesenchymal Cells by Regulating the Forkhead Box Subgroup O-3a Signaling

(2015) Zongqi Zhang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The Endothelial Transcription Factor ERG Promotes Vascular Stability and Growth through Wnt/β-Catenin Signaling

(2015) Graeme M. Birdsey et al.   DEVELOPMENTAL CELL

A possible contribution of endothelial CCN1 downregulation due to Fli1 deficiency to the development of digital ulcers in systemic sclerosis

(2015) Ryosuke Saigusa et al.   EXPERIMENTAL DERMATOLOGY

Endothelial-to-mesenchymal transition drives atherosclerosis progression

(2015) Pei-Yu Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

H3K4/H3K9me3 Bivalent Chromatin Domains Targeted by Lineage-Specific DNA Methylation Pauses Adipocyte Differentiation

(2015) Yoshihiro Matsumura et al.   MOLECULAR CELL

ngs.plot: Quick mining and visualization of next-generation sequencing data by integrating genomic databases

(2014) Li Shen et al.   BMC GENOMICS

The Endothelial-Mesenchymal Transition (EndMT) and Tissue Regeneration

(2014) Wenjing Yu et al.   Current Stem Cell Research & Therapy

Fli1 deficiency contributes to the suppression of endothelial CXCL5 expression in systemic sclerosis

(2013) Yohei Ichimura et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Interferon-γ promotes vascular remodeling in human microvascular endothelial cells by upregulating endothelin (ET)-1 and transforming growth factor (TGF) β2

(2013) Izabela Chrobak et al.   JOURNAL OF CELLULAR PHYSIOLOGY

microRNA 126 Inhibits the Transition of Endothelial Progenitor Cells to Mesenchymal Cells via the PIK3R2-PI3K/Akt Signalling Pathway

(2013) Junfeng Zhang et al.   PLoS One

Efficient Direct Reprogramming of Mature Amniotic Cells into Endothelial Cells by ETS Factors and TGFβ Suppression

(2012) Michael Ginsberg et al.   CELL

Co-ordinating Notch, BMP, and TGF-β signaling during heart valve development

(2012) Victoria C. Garside et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Erg is a crucial regulator of endocardial-mesenchymal transformation during cardiac valve morphogenesis

(2012) P. Vijayaraj et al.   DEVELOPMENT

The Transcription Factor Erg Controls Endothelial Cell Quiescence by Repressing Activity of Nuclear Factor (NF)-κB p65

(2012) Nicola H. Dryden et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ETS-related Gene (ERG) Controls Endothelial Cell Permeability via Transcriptional Regulation of the Claudin 5 (CLDN5) Gene

(2012) Lei Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ChromHMM: automating chromatin-state discovery and characterization

(2012) Jason Ernst et al.   NATURE METHODS

A novel ab initio identification system of transcriptional regulation motifs in genome DNA sequences based on direct comparison scheme of signal/noise distributions

(2012) Ryo Nakaki et al.   NUCLEIC ACIDS RESEARCH

Inflammation-Induced Endothelial-to-Mesenchymal Transition

(2011) Florian Rieder et al.   AMERICAN JOURNAL OF PATHOLOGY

Etv2/ER71 induces vascular mesoderm from Flk1+PDGFR + primitive mesoderm

(2011) H. Kataoka et al.   BLOOD

The transcription factor Erg regulates expression of histone deacetylase 6 and multiple pathways involved in endothelial cell migration and angiogenesis

(2011) G. M. Birdsey et al.   BLOOD

RhoJ is an endothelial cell-restricted Rho GTPase that mediates vascular morphogenesis and is regulated by the transcription factor ERG

(2011) L. Yuan et al.   BLOOD

Epigenetically coordinated GATA2 binding is necessary for endothelium-specificendomucinexpression

(2011) Yasuharu Kanki et al.   EMBO JOURNAL

Tumor-specific retargeting of an oncogenic transcription factor chimera results in dysregulation of chromatin and transcription

(2011) M. Patel et al.   GENOME RESEARCH

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

Endothelial Fli1 Deficiency Impairs Vascular Homeostasis

(2010) Yoshihide Asano et al.   AMERICAN JOURNAL OF PATHOLOGY

Ets-1 and Ets-2 Regulate the Expression of MicroRNA-126 in Endothelial Cells

(2010) Tamia A. Harris et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Transcription Factor Erg Inhibits Vascular Inflammation by Repressing NF-κB Activation and Proinflammatory Gene Expression in Endothelial Cells

(2010) Andrea Sperone et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vascular bed-specific regulation of the von Willebrand factor promoter in the heart and skeletal muscle

(2010) J. Liu et al.   BLOOD

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

GREAT improves functional interpretation of cis-regulatory regions

(2010) Cory Y McLean et al.   NATURE BIOTECHNOLOGY

CEAS: cis-regulatory element annotation system

(2009) Hyunjin Shin et al.   BIOINFORMATICS

PrognoScan: a new database for meta-analysis of the prognostic value of genes

(2009) Hideaki Mizuno et al.   BMC Medical Genomics

Antiinflammatory Effects of the ETS Factor ERG in Endothelial Cells Are Mediated Through Transcriptional Repression of the Interleukin-8 Gene

(2009) Lei Yuan et al.   CIRCULATION RESEARCH

Transcriptional Control of Endothelial Cell Development

(2009) Sarah De Val et al.   DEVELOPMENTAL CELL

Phosphorylation of Fli1 at Threonine 312 by Protein Kinase C   Promotes Its Interaction with p300/CREB-Binding Protein-Associated Factor and Subsequent Acetylation in Response to Transforming Growth Factor  

(2009) Y. Asano et al.   MOLECULAR AND CELLULAR BIOLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Transcription factor Erg regulates angiogenesis and endothelial apoptosis through VE-cadherin

(2008) G. M. Birdsey et al.   BLOOD

ER71 Acts Downstream of BMP, Notch, and Wnt Signaling in Blood and Vessel Progenitor Specification

(2008) Dongjun Lee et al.   Cell Stem Cell

Genome-Wide Analysis of the Zebrafish ETS Family Identifies Three Genes Required for Hemangioblast Differentiation or Angiogenesis

(2008) Feng Liu et al.   CIRCULATION RESEARCH

miR-126 Regulates Angiogenic Signaling and Vascular Integrity

(2008) Jason E. Fish et al.   DEVELOPMENTAL CELL

The Endothelial-Specific MicroRNA miR-126 Governs Vascular Integrity and Angiogenesis

(2008) Shusheng Wang et al.   DEVELOPMENTAL CELL

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY