A natural antisense lncRNA controls breast cancer progression by promoting tumor suppressor gene mRNA stability

RNA-editing enzymes ADAR1 and ADAR2 coordinately regulate the editing and expression of Ctn RNA

(2017) Aparna Anantharaman et al.   FEBS LETTERS

The regulatory roles of long non-coding RNAs in the development of chemoresistance in breast cancer

(2017) Akshay Malhotra et al.   Oncotarget

lncRNAs in development and disease: from functions to mechanisms

(2017) M. Joaquina Delás et al.   Open Biology

Transcriptome-wide analysis of natural antisense transcripts shows their potential role in breast cancer

(2017) Stephane Wenric et al.   Scientific Reports

MicroRNA 200a inhibits erythroid differentiation by targetingPDCD4andTHRB

(2016) Yanming Li et al.   BRITISH JOURNAL OF HAEMATOLOGY

Hypermethylation and Expression Silencing of PDCD4 Gene in Hepatocellular Carcinoma

(2016) Xianglian Ding et al.   MEDICINE

Long noncoding RNA FGFR3-AS1 promotes osteosarcoma growth through regulating its natural antisense transcript FGFR3

(2016) Jiabing Sun et al.   MOLECULAR BIOLOGY REPORTS

Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP)

(2016) Eric L Van Nostrand et al.   NATURE METHODS

Natural antisense RNA promotes 3′ end processing and maturation of MALAT1 lncRNA

(2016) Xinying Zong et al.   NUCLEIC ACIDS RESEARCH

MiRNA-183-5p promotes cell proliferation and inhibits apoptosis in human breast cancer by targeting the PDCD4

(2016) Yan Cheng et al.   Reproductive Biology

Functional and prognostic significance of long non-coding RNA MALAT1 as a metastasis driver in ER negative lymph node negative breast cancer

(2016) Mahdieh Jadaliha et al.   Oncotarget

miR-181b functions as an oncomiR in colorectal cancer by targeting PDCD4

(2016) Yanqing Liu et al.   Protein & Cell

Current Evidence and Future Perspectives on HuR and Breast Cancer Development, Prognosis, and Treatment

(2016) Ioly Kotta-Loizou et al.   NEOPLASIA

TANRIC: An Interactive Open Platform to Explore the Function of lncRNAs in Cancer

(2015) Jun Li et al.   CANCER RESEARCH

Post-transcriptional inducible gene regulation by natural antisense RNA

(2015) Mikio Nishizawa   Frontiers in Bioscience-Landmark

Differentiation of mammary tumors and reduction in metastasis uponMalat1lncRNA loss

(2015) Gayatri Arun et al.   GENES & DEVELOPMENT

The landscape of antisense gene expression in human cancers

(2015) O. Alejandro Balbin et al.   GENOME RESEARCH

Discovery and annotation of long noncoding RNAs

(2015) John S Mattick et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Head-to-head antisense transcription and R-loop formation promotes transcriptional activation

(2015) Raquel Boque-Sastre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The malignant phenotype in breast cancer is driven by eIF4A1-mediated changes in the translational landscape

(2015) A Modelska et al.   Cell Death & Disease

Long non-coding RNA growth arrest-specific transcript 5 in tumor biology

(2015) XIN YU et al.   Oncology Letters

Discovery and annotation of long noncoding RNAs

(2015) John S Mattick et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Natural antisense transcripts

(2014) O. Khorkova et al.   HUMAN MOLECULAR GENETICS

Post-transcriptional Regulation of Programmed Cell Death 4 (PDCD4) mRNA by the RNA-binding Proteins Human Antigen R (HuR) and T-cell Intracellular Antigen 1 (TIA1)

(2014) Callie P. Wigington et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Destabilization of nucleophosmin mRNA by the HuR/KSRP complex is required for muscle fibre formation

(2014) Anne Cammas et al.   Nature Communications

PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity

(2014) Je-Hyun Yoon et al.   Nature Communications

Biological functions of natural antisense transcripts

(2013) Andreas Werner   BMC BIOLOGY

Interleukin-1β induces tumor necrosis factor-α secretion from rat hepatocytes

(2013) Emi Yoshigai et al.   HEPATOLOGY RESEARCH

Targeting long non-coding RNA to therapeutically upregulate gene expression

(2013) Claes Wahlestedt   NATURE REVIEWS DRUG DISCOVERY

Gene regulation by antisense transcription

(2013) Vicent Pelechano et al.   NATURE REVIEWS GENETICS

Natural antisense transcript-targeted regulation of inducible nitric oxide synthase mRNA levels

(2013) Emi Yoshigai et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Downregulation of programmed cell death 4 (PDCD4) in tumorigenesis and progression of human digestive tract cancers

(2013) Gang Ma et al.   TUMOR BIOLOGY

The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression

(2012) T. Derrien et al.   GENOME RESEARCH

Novel Image Analysis Approach Quantifies Morphological Characteristics of 3D Breast Culture Acini with Varying Metastatic Potentials

(2012) Lindsey McKeen Polizzotti et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

LincRNA-p21 Suppresses Target mRNA Translation

(2012) Je-Hyun Yoon et al.   MOLECULAR CELL

Landscape of transcription in human cells

(2012) Sarah Djebali et al.   NATURE

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Pdcd4 directly binds the coding region of c-myb mRNA and suppresses its translation

(2011) P Singh et al.   ONCOGENE

The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation

(2010) Vidisha Tripathi et al.   MOLECULAR CELL

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

(2010) Rajnish A. Gupta et al.   NATURE

Delineating Genetic Alterations for Tumor Progression in the MCF10A Series of Breast Cancer Cell Lines

(2010) Mitsutaka Kadota et al.   PLoS One

Evidence for natural antisense transcript-mediated inhibition of microRNA function

(2010) Mohammad Ali Faghihi et al.   GENOME BIOLOGY

The tumour suppressor Pdcd4: recent advances in the elucidation of function and regulation

(2009) Brigitte Lankat-Buttgereit et al.   BIOLOGY OF THE CELL

Expression of estrogenicity genes in a lineage cell culture model of human breast cancer progression

(2009) Jiaqi Fu et al.   BREAST CANCER RESEARCH AND TREATMENT

Increasingly transformed MCF-10A cells have a progressively tumor-like phenotype in three-dimensional basement membrane culture

(2009) Karen M Imbalzano et al.   Cancer Cell International

Identification of Novel Gene Amplifications in Breast Cancer and Coexistence of Gene Amplification with an Activating Mutation of PIK3CA

(2009) M. Kadota et al.   CANCER RESEARCH

Structural basis for translational inhibition by the tumour suppressor Pdcd4

(2009) Portia G Loh et al.   EMBO JOURNAL

HuR recruits let-7/RISC to repress c-Myc expression

(2009) H. H. Kim et al.   GENES & DEVELOPMENT

Wrap53, a Natural p53 Antisense Transcript Required for p53 Induction upon DNA Damage

(2009) Salah Mahmoudi et al.   MOLECULAR CELL

Regulatory roles of natural antisense transcripts

(2009) Mohammad Ali Faghihi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY