Exercise Training Attenuates Obesity-Induced Skeletal Muscle Remodeling and Mitochondria-Mediated Apoptosis in the Skeletal Muscle

High Fat Diet-Induced Skeletal Muscle Wasting Is Decreased by Mesenchymal Stem Cells Administration: Implications on Oxidative Stress, Ubiquitin Proteasome Pathway Activation, and Myonuclear Apoptosis

(2016) Johanna Abrigo et al.   Oxidative Medicine and Cellular Longevity

Fatty Infiltration of Skeletal Muscle: Mechanisms and Comparisons with Bone Marrow Adiposity

(2016) Mark W. Hamrick et al.   Frontiers in Endocrinology

Molecular basis for an attenuated mitochondrial adaptive plasticity in aged skeletal muscle

(2016) Vladimir Ljubicic et al.   Aging-US

Human Adipocytes Induce Inflammation and Atrophy in Muscle Cells During Obesity

(2015) Vanessa Pellegrinelli et al.   DIABETES

Impaired exercise-induced mitochondrial biogenesis in the obese Zucker rat, despite PGC-1α induction, is due to compromised mitochondrial translation elongation

(2014) Nicholas P. Greene et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Skeletal Muscle Hypertrophy After Aerobic Exercise Training

(2014) Adam R. Konopka et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Role of PGC-1a in Sarcopenia: Etiology and Potential Intervention - A Mini-Review

(2014) Li Li Ji et al.   GERONTOLOGY

Global, regional, and national prevalence of overweight and obesity in children and adults during 1980–2013: a systematic analysis for the Global Burden of Disease Study 2013

(2014) Marie Ng et al.   LANCET

Increasing Muscle Mass Improves Vascular Function in Obese ( db/db ) Mice

(2014) Shuiqing Qiu et al.   Journal of the American Heart Association

Mitochondrial DNA Damage and Dysfunction, and Oxidative Stress Are Associated with Endoplasmic Reticulum Stress, Protein Degradation and Apoptosis in High Fat Diet-Induced Insulin Resistance Mice

(2013) Larysa V. Yuzefovych et al.   PLoS One

Testosterone exerts antiapoptotic effects against H2O2 in C2C12 skeletal muscle cells through the apoptotic intrinsic pathway

(2012) Lucía Pronsato et al.   JOURNAL OF ENDOCRINOLOGY

Role of intramyocelluar lipids in human health

(2012) Paul M. Coen et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Alterations in intrinsic mitochondrial function with aging are fiber type-specific and do not explain differential atrophy between muscles

(2011) Martin Picard et al.   AGING CELL

Apoptosis in Skeletal Myocytes: A Potential Target for Interventions against Sarcopenia and Physical Frailty – A Mini-Review

(2011) Emanuele Marzetti et al.   GERONTOLOGY

Treadmill exercise suppresses muscle cell apoptosis by increasing nerve growth factor levels and stimulating p-phosphatidylinositol 3-kinase activation in the soleus of diabetic rats

(2011) Chang-Hun Chae et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Re-evaluating lipotoxic triggers in skeletal muscle: Relating intramyocellular lipid metabolism to insulin sensitivity

(2011) Madeleen Bosma et al.   PROGRESS IN LIPID RESEARCH

Multiple Pathways to the Same End: Mechanisms of Myonuclear Apoptosis in Sarcopenia of Aging

(2011) Emanuele Marzetti et al.   TheScientificWorldJOURNAL

PTEN Inhibition Improves Muscle Regeneration in Mice Fed a High-Fat Diet

(2010) Z. Hu et al.   DIABETES

Diet-induced obesity alters signalling pathways and induces atrophy and apoptosis in skeletal muscle in a prediabetic rat model

(2010) Balindiwe Sishi et al.   EXPERIMENTAL PHYSIOLOGY

Nuclear Apoptosis Contributes to Sarcopenia

(2009) Stephen E. Alway et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

(2009) Ethan J. Anderson et al.   JOURNAL OF CLINICAL INVESTIGATION

Involvement of oxidative stress and caspase 2-mediated intrinsic pathway signaling in age-related increase in muscle cell apoptosis in mice

(2008) Melissa Braga et al.   APOPTOSIS

Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance

(2008) Timothy R. Koves et al.   Cell Metabolism

Global burden of obesity in 2005 and projections to 2030

(2008) T Kelly et al.   INTERNATIONAL JOURNAL OF OBESITY

Mitochondrial apoptotic signaling is elevated in cardiac but not skeletal muscle in the obese Zucker rat and is reduced with aerobic exercise

(2008) Jonathan M. Peterson et al.   JOURNAL OF APPLIED PHYSIOLOGY

Lower Visceral and Subcutaneous but Higher Intermuscular Adipose Tissue Depots in Patients with Growth Hormone and Insulin-Like Growth Factor I Excess Due to Acromegaly

(2008) Pamela U. Freda et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM