Anticancer strategies based on the metabolic profile of tumor cells: therapeutic targeting of the Warburg effect
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Anticancer strategies based on the metabolic profile of tumor cells: therapeutic targeting of the Warburg effect
Authors
Keywords
-
Journal
ACTA PHARMACOLOGICA SINICA
Volume 37, Issue 8, Pages 1013-1019
Publisher
Springer Nature
Online
2016-07-04
DOI
10.1038/aps.2016.47
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Halofuginone inhibits colorectal cancer growth through suppression of Akt/mTORC1 signaling and glucose metabolism
- (2015) Guo-Qing Chen et al. Oncotarget
- Coordinated regulation of protein synthesis and degradation by mTORC1
- (2014) Yinan Zhang et al. NATURE
- Lonidamine induces intracellular tumor acidification and ATP depletion in breast, prostate and ovarian cancer xenografts and potentiates response to doxorubicin
- (2014) Kavindra Nath et al. NMR IN BIOMEDICINE
- Oleanolic Acid Suppresses Aerobic Glycolysis in Cancer Cells by Switching Pyruvate Kinase Type M Isoforms
- (2014) Jia Liu et al. PLoS One
- Beyond Warburg effect – dual metabolic nature of cancer cells
- (2014) Jiansheng Xie et al. Scientific Reports
- Combined Targeting of PDK1 and EGFR Triggers Regression of Glioblastoma by Reversing the Warburg Effect
- (2013) K. K. Velpula et al. CANCER RESEARCH
- Nuclear PKM2 regulates the Warburg effect
- (2013) Weiwei Yang et al. CELL CYCLE
- mTOR Complex 2 Controls Glycolytic Metabolism in Glioblastoma through FoxO Acetylation and Upregulation of c-Myc
- (2013) Kenta Masui et al. Cell Metabolism
- Targeting 6-Phosphofructo-2-Kinase (PFKFB3) as a Therapeutic Strategy against Cancer
- (2013) B. F. Clem et al. MOLECULAR CANCER THERAPEUTICS
- mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6
- (2013) Francesca Nazio et al. NATURE CELL BIOLOGY
- Stimulation of de Novo Pyrimidine Synthesis by Growth Signaling Through mTOR and S6K1
- (2013) I. Ben-Sahra et al. SCIENCE
- PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis
- (2012) Weiwei Yang et al. CELL
- ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect
- (2012) Weiwei Yang et al. NATURE CELL BIOLOGY
- New aspects of the Warburg effect in cancer cell biology
- (2012) Steven J. Bensinger et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Emerging roles of PKM2 in cell metabolism and cancer progression
- (2012) Weibo Luo et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- mTOR: on target for novel therapeutic strategies in the nervous system
- (2012) Kenneth Maiese et al. TRENDS IN MOLECULAR MEDICINE
- The reverse Warburg effect: Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma
- (2011) Stephanos Pavlides et al. CELL CYCLE
- Understanding the metabolic basis of drug resistance
- (2011) Ubaldo E. Martinez-Outschoorn et al. CELL CYCLE
- Central role of lactic acidosis in cancer cell resistance to glucose deprivation-induced cell death
- (2011) Hao Wu et al. JOURNAL OF PATHOLOGY
- Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation
- (2011) Weiwei Yang et al. NATURE
- The reverse Warburg Effect: Glycolysis inhibitors prevent the tumor promoting effects of caveolin-1 deficient cancer associated fibroblasts
- (2010) Gloria Bonuccelli et al. CELL CYCLE
- Balancing biosynthesis and bioenergetics: metabolic programs in oncogenesis
- (2010) Jennifer F Barger et al. ENDOCRINE-RELATED CANCER
- The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein
- (2010) Zhaohui Feng et al. TRENDS IN CELL BIOLOGY
- Identification of small molecule inhibitors of pyruvate kinase M2
- (2009) Matthew G. Vander Heiden et al. BIOCHEMICAL PHARMACOLOGY
- MYC-Induced Cancer Cell Energy Metabolism and Therapeutic Opportunities
- (2009) C. V. Dang et al. CLINICAL CANCER RESEARCH
- 18F-FDG Avidity in Lymphoma Readdressed: A Study of 766 Patients
- (2009) M. Weiler-Sagie et al. JOURNAL OF NUCLEAR MEDICINE
- Proteomics-based identification of two novel direct targets of hypoxia-inducible factor-1 and their potential roles in migration/invasion of cancer cells
- (2009) Shi-Hua Liao et al. PROTEOMICS
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Expression of SGLT1, Bcl-2 and p53 in Primary Pancreatic Cancer Related to Survival
- (2008) Veerle F. Casneuf et al. CANCER INVESTIGATION
- The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
- (2008) Ralph J. DeBerardinis et al. Cell Metabolism
- The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C
- (2008) Valeria Facchinetti et al. EMBO JOURNAL
- Metabolic acidosis and the importance of balanced equations
- (2008) Andrew N. Lane et al. Metabolomics
- Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth
- (2008) B. Clem et al. MOLECULAR CANCER THERAPEUTICS
- Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
- (2008) William G. Kaelin et al. MOLECULAR CELL
- Pyruvate kinase M2 is a phosphotyrosine-binding protein
- (2008) Heather R. Christofk et al. NATURE
- Magnetic resonance imaging of pH in vivo using hyperpolarized 13C-labelled bicarbonate
- (2008) Ferdia A. Gallagher et al. NATURE
- The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
- (2008) Heather R. Christofk et al. NATURE
- Human Skin Keloid Fibroblasts Display Bioenergetics of Cancer Cells
- (2007) Annette S. Vincent et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started