Journal
CURRENT STEM CELL RESEARCH & THERAPY
Volume 14, Issue 4, Pages 293-304Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1574888X14666181205120110
Keywords
Endometrial stem cells; label-retaining cells; side population cells; menstrual blood-derived stem cells; bone marrow-derived stem cells; Asherman's syndrome
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Funding
- National Natural Science Foundation of China [81571391, 81401166, 30900847]
- Jiangsu Provincial Medical Youth Talent [QNRC2016006]
- Nanjing Medical Science Development Project [JQX2014004, ZKX16042]
- MRC [G1000816] Funding Source: UKRI
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Monthly changes in the endometrial cycle indicate the presence of endometrial stem cells. In recent years, various stem cells that exist in the endometrium have been identified and characterized. Additionally, many studies have shown that Bone Marrow Mesenchymal Stem Cells (BM-MSCs) provide an alternative source for regenerating the endometrium and repairing endometrial injury. This review discusses the origin of endometrial stem cells, the characteristics and main biomarkers among five types of putative endometrial stem cells, applications of endometrium-derived stem cells and menstrual blood-derived stem cells, the association between BM-MSCs and endometrial stem cells, and progress in repairing endometrial injury.
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