SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-Dependent Tumors

Published 2019 View Full Article

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Title
SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-Dependent Tumors
Authors
Keywords
targeted therapies, adaptive resistance, ERK signaling, SHP2, RTK signaling, RAS, BRAF, MEK, FGFR, triple-negative breast cancer, TNBC
Journal
Cell Reports
Volume 26, Issue 1, Pages 65-78.e5
Publisher
Elsevier BV
Online
2019-01-02
DOI
10.1016/j.celrep.2018.12.013

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