Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation

Published 2019 View Full Article

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Title
Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation
Authors
Keywords
synthetic lethality, PGD, OXPHOS, tumor metabolism, metabolic vulnerability, fumarate hydratase, redox homeostasis, functional genomics, hereditary leiomyomatosis renal cell carcinoma, pentose phosphate pathway
Journal
Cell Reports
Volume 26, Issue 2, Pages 469-482.e5
Publisher
Elsevier BV
Online
2019-01-09
DOI
10.1016/j.celrep.2018.12.043

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