Reliability of Whole-Exome Sequencing for Assessing Intratumor Genetic Heterogeneity

Published 2018 View Full Article

Authors

Keywords

massively parallel sequencing, whole-exome sequencing, somatic mutations, intratumor genetic heterogeneity, multi-region profiling, breast cancer, mutational signatures, mappability, subclonal

Journal

Cell Reports

Volume 25, Issue 6, Pages 1446-1457

Publisher

Elsevier BV

Online

2018-11-07

DOI

10.1016/j.celrep.2018.10.046

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