OCT4 maintains self-renewal and reverses senescence in human hair follicle mesenchymal stem cells through the downregulation of p21 by DNA methyltransferases

Potential roles of DNA methylation in the initiation and establishment of replicative senescence revealed by array-based methylome and transcriptome analyses

(2017) Mizuho Sakaki et al.   PLoS One

Derepression ofhTERTgene expression promotes escape from oncogene-induced cellular senescence

(2016) Priyanka L. Patel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-302 regulates pluripotency, teratoma formation and differentiation in stem cells via an AKT1/OCT4-dependent manner

(2016) H-L Li et al.   Cell Death & Disease

Of Mice and Man: Differential DNMT Dependence in Mammalian ESCs

(2015) Ozren Bogdanović et al.   Cell Stem Cell

Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells

(2015) Jing Liao et al.   NATURE GENETICS

HighOCT4and Lowp16INK4AExpressions DetermineIn VitroLifespan of Mesenchymal Stem Cells

(2015) Carla A. Piccinato et al.   Stem Cells International

Epigenomic Analysis of Multilineage Differentiation of Human Embryonic Stem Cells

(2013) Wei Xie et al.   CELL

Oct4 and Sox2 overexpression improves the proliferation and differentiation of bone mesenchymal stem cells in Xiaomeishan porcine

(2013) Y.X. Fan et al.   GENETICS AND MOLECULAR RESEARCH

Dynamics of DNA demethylation

(2013) Tal Nawy   NATURE METHODS

Transcriptional repression of Bmp2 by p21Waf1/Cip1 links quiescence to neural stem cell maintenance

(2013) Eva Porlan et al.   NATURE NEUROSCIENCE

Runx1 and p21 synergistically limit the extent of hair follicle stem cell quiescence in vivo

(2013) J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Oct4-pRb Axis, Controlled by MiR-335, Integrates Stem Cell Self-Renewal and Cell Cycle Control

(2013) Stefan Schoeftner et al.   STEM CELLS

Concise Review: The Sox2-Oct4 Connection: Critical Players in a Much Larger Interdependent Network Integrated at Multiple Levels

(2013) Angie Rizzino   STEM CELLS

Induced Pluripotent Stem Cells from Human Hair Follicle Mesenchymal Stem Cells

(2012) Yimei Wang et al.   Stem Cell Reviews and Reports

CD49f Enhances Multipotency and Maintains Stemness Through the Direct Regulation of OCT4 and SOX2

(2012) Kyung-Rok Yu et al.   STEM CELLS

Aging effects on DNA methylation modules in human brain and blood tissue

(2012) Steve Horvath et al.   GENOME BIOLOGY

Knockdown of p21Cip1/Waf1 enhances proliferation, the expression of stemness markers, and osteogenic potential in human mesenchymal stem cells

(2011) Tu-Lai Yew et al.   AGING CELL

Constitutive activation of the MEK/ERK pathway inhibits intestinal epithelial cell differentiation

(2011) Etienne Lemieux et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Importance of Sox2 in maintenance of cell proliferation and multipotency of mesenchymal stem cells in low-density culture

(2011) D. S. Yoon et al.   CELL PROLIFERATION

Oct4 links multiple epigenetic pathways to the pluripotency network

(2011) Junjun Ding et al.   CELL RESEARCH

Activation of Bmp2-Smad1 Signal and Its Regulation by Coordinated Alteration of H3K27 Trimethylation in Ras-Induced Senescence

(2011) Atsushi Kaneda et al.   PLoS Genetics

The role of telomeres and telomerase in stem cell aging

(2010) Ignacio Flores et al.   FEBS LETTERS

Reprogramming the pluripotent cell cycle: Restoration of an abbreviated G1 phase in human induced pluripotent stem (iPS) cells

(2010) Prachi N. Ghule et al.   JOURNAL OF CELLULAR PHYSIOLOGY

OCT4A contributes to the stemness and multi-potency of human umbilical cord blood-derived multipotent stem cells (hUCB–MSCs)

(2009) Kwang-Won Seo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Oct-4 controls cell-cycle progression of embryonic stem cells

(2009) Jungwoon Lee et al.   BIOCHEMICAL JOURNAL

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Linking the p53 tumour suppressor pathway to somatic cell reprogramming

(2009) Teruhisa Kawamura et al.   NATURE

Regulation of Adipose Tissue Stromal Cells Behaviors by Endogenic Oct4 Expression Control

(2009) Jung Hwan Kim et al.   PLoS One

Regulation of Stem Cell Pluripotency and Differentiation Involves a Mutual Regulatory Circuit of the Nanog, OCT4, and SOX2 Pluripotency Transcription Factors With Polycomb Repressive Complexes and Stem Cell microRNAs

(2009) Vasundhra Kashyap et al.   STEM CELLS AND DEVELOPMENT

Stem Cells, the Molecular Circuitry of Pluripotency and Nuclear Reprogramming

(2008) Rudolf Jaenisch et al.   CELL

Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells

(2008) Xi Chen et al.   CELL

An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells

(2008) Jonghwan Kim et al.   CELL

Promoter CpG Methylation Contributes to ES Cell Gene Regulation in Parallel with Oct4/Nanog, PcG Complex, and Histone H3 K4/K27 Trimethylation

(2008) Shaun D. Fouse et al.   Cell Stem Cell

Oct4/Sox2-Regulated miR-302 Targets Cyclin D1 in Human Embryonic Stem Cells

(2008) D. A. Greer Card et al.   MOLECULAR AND CELLULAR BIOLOGY

Effects of Ectopic Nanog and Oct4 Overexpression on Mesenchymal Stem Cells

(2008) Tong Ming Liu et al.   STEM CELLS AND DEVELOPMENT