Metformin induces apoptosis in mesenchymal stromal cells and dampens their therapeutic efficacy in infarcted myocardium

Metformin Enhances Osteogenesis and Suppresses Adipogenesis of Human Chorionic Villous Mesenchymal Stem Cells

(2017) Qiaoli Gu et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Clinical Trials with Mesenchymal Stem Cells: An Update

(2016) Tiziana Squillaro et al.   CELL TRANSPLANTATION

The effect of diabetes on the wound healing potential of adipose-tissue derived stem cells

(2016) Sue Min Kim et al.   International Wound Journal

Human Umbilical Cord-Derived Mesenchymal Stromal Cells Improve Left Ventricular Function, Perfusion, and Remodeling in a Porcine Model of Chronic Myocardial Ischemia

(2016) Chuan-Bin Liu et al.   Stem Cells Translational Medicine

Progenitor Cell Dysfunctions Underlie Some Diabetic Complications

(2015) Melanie Rodrigues et al.   AMERICAN JOURNAL OF PATHOLOGY

Diabetes reduces mesenchymal stem cells in fracture healing through a TNFα-mediated mechanism

(2015) Kang I. Ko et al.   DIABETOLOGIA

Pericytes, mesenchymal stem cells and their contributions to tissue repair

(2015) Suet-Ping Wong et al.   PHARMACOLOGY & THERAPEUTICS

Hyperglycemic Stress Impairs the Stemness Capacity of Kidney Stem Cells in Rats

(2015) Guang Yang et al.   PLoS One

Low dose radiation induced senescence of human mesenchymal stromal cells and impaired the autophagy process

(2015) Nicola Alessio et al.   Oncotarget

Metformin: From Mechanisms of Action to Therapies

(2014) Marc Foretz et al.   Cell Metabolism

Inhibition of the endogenous CSE/H2S system contributes to hypoxia and serum deprivation-induced apoptosis in mesenchymal stem cells

(2014) CONGSHENG LI et al.   Molecular Medicine Reports

Cell Senescence Abrogates the Therapeutic Potential of Human Mesenchymal Stem Cells in the Lethal Endotoxemia Model

(2014) Juan Carlos Sepúlveda et al.   STEM CELLS

Therapeutic efficacy of bone marrow-derived mononuclear cells in diabetic polyneuropathy is impaired with aging or diabetes

(2014) Masaki Kondo et al.   Journal of Diabetes Investigation

Restoration of angiogenic capacity of diabetes-insulted mesenchymal stem cells by oxytocin

(2013) Yong Kim et al.   BMC CELL BIOLOGY

Prolyl Hydroxylase Domain Protein 2 Silencing Enhances the Survival and Paracrine Function of Transplanted Adipose-Derived Stem Cells in Infarcted Myocardium

(2013) Wei Eric Wang et al.   CIRCULATION RESEARCH

Metformin and cancer

(2013) Christos V. Rizos et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Metformin Therapy and Risk of Cancer in Patients with Type 2 Diabetes: Systematic Review

(2013) Monica Franciosi et al.   PLoS One

Number of circulating pro-angiogenic cells, growth factor and anti-oxidative gene profiles might be altered in type 2 diabetes with and without diabetic foot syndrome

(2013) Witold N Nowak et al.   Journal of Diabetes Investigation

Diabetes treatments and cancer risk: the importance of considering aspects of drug exposure

(2013) Jeremy J Walker et al.   Lancet Diabetes & Endocrinology

Mesenchymal Stem Cells in Tissue Repair

(2013) Amy M. DiMarino et al.   Frontiers in Immunology

Metformin selectively affects human glioblastoma tumor-initiating cell viability

(2012) Roberto Würth et al.   CELL CYCLE

Mortality After Incident Cancer in People With and Without Type 2 Diabetes: Impact of metformin on survival

(2012) C. J. Currie et al.   DIABETES CARE

Towards regenerative therapy for cardiac disease

(2012) Leon M Ptaszek et al.   LANCET

The Antidiabetic Effect of Mesenchymal Stem Cells Is Unrelated to Their Transdifferentiation Potential But to Their Capability to Restore Th1/Th2 Balance and to Modify the Pancreatic Microenvironment

(2012) Fernando Ezquer et al.   STEM CELLS

The effects of thiazolidinediones on human bone marrow stromal cell differentiation in vitro and in thiazolidinedione-treated patients with type 2 diabetes

(2012) George R. Beck et al.   Translational Research

Different populations and sources of human mesenchymal stem cells (MSC): A comparison of adult and neonatal tissue-derived MSC

(2011) Ralf Hass et al.   Cell Communication and Signaling

Getting to the Heart of Myocardial Stem Cells and Cell Therapy

(2011) Tara L. Rasmussen et al.   CIRCULATION

Increased expression of pigment epithelium-derived factor in aged mesenchymal stem cells impairs their therapeutic efficacy for attenuating myocardial infarction injury‡

(2011) Hongliang Liang et al.   EUROPEAN HEART JOURNAL

Metformin, Independent of AMPK, Inhibits mTORC1 in a Rag GTPase-Dependent Manner

(2010) Adem Kalender et al.   Cell Metabolism

Glucose-lowering agents and cancer mortality rates in type 2 diabetes: assessing effects of time-varying exposure

(2010) S. L. Bowker et al.   DIABETOLOGIA

Metformin Associated With Lower Cancer Mortality in Type 2 Diabetes: ZODIAC-16

(2009) G. W.D. Landman et al.   DIABETES CARE

Targeting the phosphoinositide 3-kinase pathway in cancer

(2009) Pixu Liu et al.   NATURE REVIEWS DRUG DISCOVERY

BAD: undertaker by night, candyman by day

(2009) N N Danial   ONCOGENE

Aging and Diabetes Impair the Neovascular Potential of Adipose-Derived Stromal Cells

(2009) Samyra El-ftesi et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation

(2008) A. Y. Choo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL