Growth Differentiation Factor 11 treatment leads to neuronal and vascular improvements in the hippocampus of aged mice

Growth differentiation factor 11 improves neurobehavioral recovery and stimulates angiogenesis in rats subjected to cerebral ischemia/reperfusion

(2018) Jingxi Ma et al.   BRAIN RESEARCH BULLETIN

GDF11 Rejuvenates Cerebrovascular Structure and Function in an Animal Model of Alzheimer’s Disease

(2018) Wei Zhang et al.   JOURNAL OF ALZHEIMERS DISEASE

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults

(2018) Shawn F. Sorrells et al.   NATURE

Growth Differentiation Factor 11 Promotes Neurovascular Recovery After Stroke in Mice

(2018) Lu Lu et al.   Frontiers in Cellular Neuroscience

Tet2 Rescues Age-Related Regenerative Decline and Enhances Cognitive Function in the Adult Mouse Brain

(2018) Geraldine Gontier et al.   Cell Reports

Skeletal myofiber vascular endothelial growth factor is required for the exercise training-induced increase in dentate gyrus neuronal precursor cells

(2017) Benjamin Rich et al.   JOURNAL OF PHYSIOLOGY-LONDON

Human umbilical cord plasma proteins revitalize hippocampal function in aged mice

(2017) Joseph M. Castellano et al.   NATURE

The effects of aging in the hippocampus and cognitive decline

(2017) Luis E.B. Bettio et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Huntington’s Disease iPSC-Derived Brain Microvascular Endothelial Cells Reveal WNT-Mediated Angiogenic and Blood-Brain Barrier Deficits

(2017) Ryan G. Lim et al.   Cell Reports

GDF11 Protects against Endothelial Injury and Reduces Atherosclerotic Lesion Formation in Apolipoprotein E-Null Mice

(2016) Wen Mei et al.   MOLECULAR THERAPY

Ageing, neurodegeneration and brain rejuvenation

(2016) Tony Wyss-Coray   NATURE

Glio-vascular changes during ageing in wild-type and Alzheimer׳s disease-like APP/PS1 mice

(2015) C.S. Janota et al.   BRAIN RESEARCH

Coupling of neurogenesis and angiogenesis after ischemic stroke

(2015) Linhui Ruan et al.   BRAIN RESEARCH

GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration

(2015) Marc A. Egerman et al.   Cell Metabolism

Circulating Growth Differentiation Factor 11/8 Levels Decline With AgeNovelty and Significance

(2015) Tommaso Poggioli et al.   CIRCULATION RESEARCH

GDF11 Does Not Rescue Aging-Related Pathological HypertrophyNovelty and Significance

(2015) Shavonn C. Smith et al.   CIRCULATION RESEARCH

Control of cerebrovascular patterning by neural activity during postnatal development

(2015) Baptiste Lacoste et al.   MECHANISMS OF DEVELOPMENT

Activity Dependency and Aging in the Regulation of Adult Neurogenesis

(2015) Gerd Kempermann   Cold Spring Harbor Perspectives in Biology

Markers for blood-brain barrier integrity: how appropriate is Evans blue in the twenty-first century and what are the alternatives?

(2015) Norman R. Saunders et al.   Frontiers in Neuroscience

Use of labeled tomato lectin for imaging vasculature structures

(2014) Richard T. Robertson et al.   HISTOCHEMISTRY AND CELL BIOLOGY

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice

(2014) Saul A Villeda et al.   NATURE MEDICINE

ALK5-dependent TGF-β signaling is a major determinant of late-stage adult neurogenesis

(2014) Yingbo He et al.   NATURE NEUROSCIENCE

Regulation and Function of Adult Neurogenesis: From Genes to Cognition

(2014) James B. Aimone et al.   PHYSIOLOGICAL REVIEWS

Vascular and Neurogenic Rejuvenation of the Aging Mouse Brain by Young Systemic Factors

(2014) L. Katsimpardi et al.   SCIENCE

Restoring Systemic GDF11 Levels Reverses Age-Related Dysfunction in Mouse Skeletal Muscle

(2014) M. Sinha et al.   SCIENCE

Setting-up an In Vitro Model of Rat Blood-brain Barrier (BBB): A Focus on BBB Impermeability and Receptor-mediated Transport

(2014) Yves Molino et al.   Jove-Journal of Visualized Experiments

Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy

(2013) Francesco S. Loffredo et al.   CELL

Vascular Risk Factors and Neurodegeneration in Ageing Related Dementias: Alzheimer’s Disease and Vascular Dementia

(2013) Rufus Akinyemi et al.   Current Alzheimer Research

Long-Term Exercise Is a Potent Trigger for ΔFosB Induction in the Hippocampus along the dorso–ventral Axis

(2013) Takeshi Nishijima et al.   PLoS One

Ageing as a Risk Factor for Disease

(2012) Teresa Niccoli et al.   CURRENT BIOLOGY

Adult neurogenesis, neuroinflammation and therapeutic potential of adult neural stem cells

(2012) Philippe Taupin   International Journal of Medical Sciences

The ageing systemic milieu negatively regulates neurogenesis and cognitive function

(2011) Saul A. Villeda et al.   NATURE

A pathophysiological framework of hippocampal dysfunction in ageing and disease

(2011) Scott A. Small et al.   NATURE REVIEWS NEUROSCIENCE

Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

(2011) Berislav V. Zlokovic   NATURE REVIEWS NEUROSCIENCE

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions

(2011) Guo-li Ming et al.   NEURON

The Mouse Blood-Brain Barrier Transcriptome: A New Resource for Understanding the Development and Function of Brain Endothelial Cells

(2010) Richard Daneman et al.   PLoS One

Isolation and Expansion of the Adult Mouse Neural Stem Cells Using the Neurosphere Assay

(2010) Hassan Azari et al.   Jove-Journal of Visualized Experiments

Age-Related Vascular Pathology in Transgenic Mice Expressing Presenilin 1-Associated Familial Alzheimer's Disease Mutations

(2009) Miguel A. Gama Sosa et al.   AMERICAN JOURNAL OF PATHOLOGY

Adult SVZ Stem Cells Lie in a Vascular Niche: A Quantitative Analysis of Niche Cell-Cell Interactions

(2008) Qin Shen et al.   Cell Stem Cell